A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner
Stemmer, Willem P C, Schellenberger, Volker, Wang, Chia-wei, Geething, Nathan C, Spink, Benjamin J, Campbell, Andrew, To, Wayne, Scholle, Michael D, Yin, Yong, Yao, Yi, Bogin, Oren, Cleland, Jeffrey L, Silverman, Joshua
Published in Nature biotechnology (01.12.2009)
Published in Nature biotechnology (01.12.2009)
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Journal Article
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
Cua, Daniel J, Sherlock, Jonathan, Chen, Yi, Murphy, Craig A, Joyce, Barbara, Seymour, Brian, Lucian, Linda, To, Wayne, Kwan, Sylvia, Churakova, Tatyana, Zurawski, Sandra, Wiekowski, Maria, Lira, Sergio A, Gorman, Daniel, Kastelein, Robert A, Sedgwick, Jonathon D
Published in Nature (London) (13.02.2003)
Published in Nature (London) (13.02.2003)
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Journal Article
A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R
Parham, Christi, Chirica, Madaline, Timans, Jacqueline, Vaisberg, Elena, Travis, Marilyn, Cheung, Jeanne, Pflanz, Stefan, Zhang, Rebecca, Singh, Komal P., Vega, Felix, To, Wayne, Wagner, Janet, O’Farrell, Anne-Marie, McClanahan, Terrill, Zurawski, Sandra, Hannum, Charles, Gorman, Daniel, Rennick, Donna M., Kastelein, Robert A., de Waal Malefyt, Rene, Moore, Kevin W.
Published in The Journal of immunology (1950) (01.06.2002)
Published in The Journal of immunology (1950) (01.06.2002)
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Journal Article
Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose
Geething, Nathan C, To, Wayne, Spink, Benjamin J, Scholle, Michael D, Wang, Chia-wei, Yin, Yong, Yao, Yi, Schellenberger, Volker, Cleland, Jeffrey L, Stemmer, Willem P C, Silverman, Joshua
Published in PloS one (14.04.2010)
Published in PloS one (14.04.2010)
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Journal Article
CCL27-CCR10 interactions regulate T cell-mediated skin inflammation
Homey, Bernhard, Zlotnik, Albert, Alenius, Harri, Müller, Anja, Soto, Hortensia, Bowman, Edward P, Yuan, Wei, McEvoy, Leslie, Lauerma, Antti I, Assmann, Till, Bünemann, Erich, Lehto, Maili, Wolff, Henrik, Yen, David, Marxhausen, Heather, To, Wayne, Sedgwick, Jonathon, Ruzicka, Thomas, Lehmann, Percy
Published in Nature medicine (01.02.2002)
Published in Nature medicine (01.02.2002)
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Journal Article
Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains
Silverman, Joshua, Stemmer, Willem Pim C, Lu, Qiang, Bakker, Alice, To, Wayne, Duguay, Amy, Alba, Ben M, Smith, Richard, Rivas, Alberto, Li, Peng, Le, Hon, Whitehorn, Erik, Moore, Kevin W, Swimmer, Candace, Perlroth, Victor, Vogt, Martin, Kolkman, Joost
Published in Nature biotechnology (01.12.2005)
Published in Nature biotechnology (01.12.2005)
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Journal Article
Abstract B233: c-Met antagonist Avimer™ polypeptide that exhibits potent in vivo and in vitro inhibitor activity
Cho, Song, Smith, Richard, Duguay, Amy, Li, Peng, Bakker, Alice, Alba, Ben, Thomas, Melissa, To, Wayne, Silverman, Josh, Swimmer, Candace, Moore, Kevin, Strout, Patrick, Bobofchak, Kevin, McCarthy, Mike, Pemmaraju, Kalyani, Lacourciere, Gerard, Zhou, Qin, Damschroder, Melissa, Wu, Herren, Coats, Steve, Kamal, Adeela
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Journal Article
MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES
Clizbe, Lane A, Charles, Stephen A, Benoit, Didier G, To, Wayne, Perlroth, Daniel Victor
Year of Publication 20.06.2024
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Year of Publication 20.06.2024
Patent
Multifunctional zwitterionic polymer conjugates
Clizbe, Lane A, Charles, Stephen A, Benoit, Didier G, Perlroth, D. Victor, To, Wayne
Year of Publication 21.11.2023
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Year of Publication 21.11.2023
Patent
Extended recombinant polypeptides and compositions comprising same
Stemmer, Willem P, To, Wayne, Geething, Nathan, Silverman, Joshua, Wang, Chia-wei, Schellenberger, Volker, Cleland, Jeffrey L, Spink, Benjamin
Year of Publication 27.08.2024
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Year of Publication 27.08.2024
Patent
MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES
Clizbe, Lane A, Charles, Stephen A, Benoit, Didier G, Perlroth, D. Victor, To, Wayne
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
Patent
Erratum: Corrigendum: Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains
Silverman, Joshua, Lu, Qiang, Bakker, Alice, To, Wayne, Duguay, Amy, Alba, Ben M, Smith, Richard, Rivas, Alberto, Li, Peng, Le, Hon, Whitehorn, Erik, Moore, Kevin W, Swimmer, Candace, Perlroth, Victor, Vogt, Martin, Kolkman, Joost, Stemmer, Willem Pim C
Published in Nature biotechnology (01.02.2006)
Published in Nature biotechnology (01.02.2006)
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Journal Article
FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES
Charles, Stephen A, Song, Li, To, Wayne, Perlroth, Daniel Victor, Benoit, Didier, Aggen, James, Linsell, Martin
Year of Publication 08.06.2023
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Year of Publication 08.06.2023
Patent
Factor VIII zwitterionic polymer conjugates
Charles, Stephen A, Song, Li, To, Wayne, Perlroth, Daniel Victor, Benoit, Didier, Aggen, James, Linsell, Martin
Year of Publication 28.02.2023
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Year of Publication 28.02.2023
Patent
Corrigendum: Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains
Silverman, Joshua, Lu, Qiang, Bakker, Alice, To, Wayne, Duguay, Amy, Alba, Ben M, Smith, Richard, Rivas, Alberto, Li, Peng, Le, Hon, Whitehorn, Erik, Moore, Kevin W, Swimmer, Candace, Perlroth, Victor, Vogt, Martin, Kolkman, Joost, Stemmer, Willem Pim C
Published in Nature biotechnology (01.02.2006)
Published in Nature biotechnology (01.02.2006)
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Journal Article
Butyrylcholinesterase zwitterionic polymer conjugates
Charles, Stephen A, To, Wayne, Perlroth, Daniel Victor, Huang, Xiaojian, Benoit, Didier, Linsell, Martin
Year of Publication 27.07.2021
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Year of Publication 27.07.2021
Patent
EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
Stemmer, Willem P, To, Wayne, Geething, Nathan, Cleland, Jerrfey L, Silverman, Joshua, Wang, Chia-wei, Schellenberger, Volker, Spink, Benjamin
Year of Publication 09.09.2021
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Year of Publication 09.09.2021
Patent
FACTOR VIII ZWITTERIONIC POLYMER CONJUGATES
Charles, Stephen A, Song, Li, Perlroth, D. Victor, To, Wayne, Benoit, Didier, Aggen, James, Linsell, Martin
Year of Publication 20.08.2020
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Year of Publication 20.08.2020
Patent
Factor VIII zwitterionic polymer conjugates
Charles, Stephen A, Song, Li, Perlroth, D. Victor, To, Wayne, Benoit, Didier, Aggen, James, Linsell, Martin
Year of Publication 07.07.2020
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Year of Publication 07.07.2020
Patent