The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies
Nahimana, Aimable, Attinger, Antoine, Aubry, Dominique, Greaney, Peter, Ireson, Christopher, Thougaard, Annemette V., Tjørnelund, Jette, Dawson, Keith M., Dupuis, Marc, Duchosal, Michel A.
Published in Blood (02.04.2009)
Published in Blood (02.04.2009)
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Journal Article
A Phase 1 Pharmacokinetic and Pharmacodynamic Study of the Histone Deacetylase Inhibitor Belinostat in Patients with Advanced Solid Tumors
STEELE, Nicola L, PLUMB, Jane A, DEBONO, Johann S, VIDAL, Laura, TJØRNELUND, Jette, KNOBLAUCH, Poul, RASMUSSEN, Annie, CHEAN ENG OOI, BUHL-JENSEN, Peter, BROWN, Robert, EVANS, T. R. Jeffry
Published in Clinical cancer research (01.02.2008)
Published in Clinical cancer research (01.02.2008)
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Journal Article
Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy
Martin, Elke, Thougaard, Annemette Vinding, Grauslund, Morten, Jensen, Peter B, Bjorkling, Fredrik, Hasinoff, Brian B, Tjørnelund, Jette, Sehested, Maxwell, Jensen, Lars H
Published in Toxicology (Amsterdam) (08.01.2009)
Published in Toxicology (Amsterdam) (08.01.2009)
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Journal Article
Synthesis and Antitumor Effect in Vitro and in Vivo of Substituted 1,3-Dihydroindole-2-ones
Christensen, Mette K, Erichsen, Kamille D, Trojel-Hansen, Christina, Tjørnelund, Jette, Nielsen, Søren J, Frydenvang, Karla, Johansen, Tommy N, Nielsen, Birgitte, Sehested, Maxwell, Jensen, Peter B, Ikaunieks, Martins, Zaichenko, Andrei, Loza, Einars, Kalvinsh, Ivars, Björkling, Fredrik
Published in Journal of medicinal chemistry (14.10.2010)
Published in Journal of medicinal chemistry (14.10.2010)
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Journal Article
Nicotinamide Phosphoribosyltransferase Inhibitors, Design, Preparation, and Structure–Activity Relationship
Christensen, Mette K, Erichsen, Kamille D, Olesen, Uffe H, Tjørnelund, Jette, Fristrup, Peter, Thougaard, Annemette, Nielsen, Søren Jensby, Sehested, Maxwell, Jensen, Peter B, Loza, Einars, Kalvinsh, Ivars, Garten, Antje, Kiess, Wieland, Björkling, Fredrik
Published in Journal of medicinal chemistry (27.11.2013)
Published in Journal of medicinal chemistry (27.11.2013)
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Journal Article
LC–MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma
Kiesel, Brian F., Parise, Robert A., Tjørnelund, Jette, Christensen, Mette K., Loza, Einars, Tawbi, Hussein, Chu, Edward, Kummar, Shivaani, Beumer, Jan H.
Published in Journal of pharmaceutical and biomedical analysis (01.07.2013)
Published in Journal of pharmaceutical and biomedical analysis (01.07.2013)
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Journal Article
Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates
Warren, Katherine E., McCully, Cindy, Dvinge, Henrik, Tjørnelund, Jette, Sehested, Maxwell, Lichenstein, Henri S., Balis, Frank M.
Published in Cancer chemotherapy and pharmacology (01.08.2008)
Published in Cancer chemotherapy and pharmacology (01.08.2008)
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Journal Article
Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines
Dejligbjerg, Marielle, Grauslund, Morten, Christensen, Ib Jarle, Tjørnelund, Jette, Buhl Jensen, Peter, Sehested, Maxwell
Published in Cancer biomarkers : section A of Disease markers (01.01.2008)
Published in Cancer biomarkers : section A of Disease markers (01.01.2008)
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Journal Article
Coelectroosmotic separations of anions in non-aqueous capillary electrophoresis
Tjørnelund, Jette, Bazzanella, Alexis, Lochmann, Holger, Bächmann, Knut
Published in Journal of Chromatography A (19.06.1998)
Published in Journal of Chromatography A (19.06.1998)
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Journal Article
Simultaneous quantitative determination of the major phase I and II metabolites of ibuprofen in biological fluids by high-performance liquid chromatography on dynamically modified silica
Kepp, Dorte R., Sidelmann, Ulla G., Tjørnelund, Jette, Hansen, Steen H.
Published in Journal of chromatography. B, Biomedical sciences and applications (29.08.1997)
Published in Journal of chromatography. B, Biomedical sciences and applications (29.08.1997)
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Journal Article
Separation of basic drug substances of very similar structure using micellar electrokinetic chromatography
Hansen, Steen Honoré, Bjørnsdottir, Inga, Tjørnelund, Jette
Published in Journal of pharmaceutical and biomedical analysis (01.04.1995)
Published in Journal of pharmaceutical and biomedical analysis (01.04.1995)
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Journal Article
Conference Proceeding
Determination of oxytetracycline and its degradation products by high-performance liquid chromatography–tandem mass spectrometry in manure-containing anaerobic test systems
Loke, Marie-Louise, Jespersen, Sonja, Vreeken, Rob, Halling-Sørensen, Bent, Tjørnelund, Jette
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.01.2003)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.01.2003)
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Journal Article
Interim Results of a Phase I/II Clinical Trial of Belinostat in Combination with Idarubicin in Patients with AML Not Suitable for Standard Intensive Therapy
Schlenk, Richard, Sohlbach, Kristina, Hütter, Marie-Luise, Ceballos, Patrice, Fegueux, Nathalie, Raffoux, Emmanuel, Dombret, Herve, Dennis, Mike, Tomlins, Jo, Tjørnelund, Jette, Neubauer, Andreas
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
Evaluation of the topoisomerase ΙΙ-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy
MARTIN, Elke, THOUGAARD, Annemette Vinding, GRAUSLUND, Morten, JENSEN, Peter B, BJORKLING, Fredrik, HASINOFF, Brian B, TJØRNELUND, Jette, SEHESTED, Maxwell, JENSEN, Lars H
Published in Toxicology (Amsterdam) (2009)
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Published in Toxicology (Amsterdam) (2009)
Journal Article