Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus
Uchiyama, Satoshi, Döhrmann, Simon, Timmer, Anjuli M, Dixit, Neha, Ghochani, Mariam, Bhandari, Tamara, Timmer, John C, Sprague, Kimberly, Bubeck-Wardenburg, Juliane, Simon, Scott I, Nizet, Victor
Published in Frontiers in immunology (16.11.2015)
Published in Frontiers in immunology (16.11.2015)
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Journal Article
Profiling constitutive proteolytic events in vivo
Timmer, John C, Enoksson, Mari, Wildfang, Eric, Zhu, Wenhong, Igarashi, Yoshinobu, Denault, Jean-Benard, Ma, Yuliang, Dummitt, Benjamin, Chang, Yie-Hwa, Mast, Alan E, Eroshkin, Alexey, Smith, Jeffrey W, Tao, W Andy, Salvesen, Guy S
Published in Biochemical journal (01.10.2007)
Published in Biochemical journal (01.10.2007)
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Journal Article
Streptolysin O Promotes Group A Streptococcus Immune Evasion by Accelerated Macrophage Apoptosis
Timmer, Anjuli M., Timmer, John C., Pence, Morgan A., Hsu, Li-Chung, Ghochani, Mariam, Frey, Terrence G., Karin, Michael, Salvesen, Guy S., Nizet, Victor
Published in The Journal of biological chemistry (09.01.2009)
Published in The Journal of biological chemistry (09.01.2009)
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Journal Article
Structural and kinetic determinants of protease substrates
Snipas, Scott J, Salvesen, Guy S, Regan, Tim, Timmer, John C, Eroshkin, Alexey M, Pop, Cristina, Zhu, Wenhong, Riedl, Stefan J
Published in Nature structural & molecular biology (01.10.2009)
Published in Nature structural & molecular biology (01.10.2009)
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Journal Article
INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses
Sulzmaier, Florian J, Kern, Nadja, Ahn, Sae Jeong, Polovina, Anya, Ho, Jason, Hussain, Abrahim, Cyprus, Garrett, Macedo, Chelsie, Pandit, Rajay, Crago, William, Rowell, Emily, Timmer, John C, Eckelman, Brendan P
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
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Journal Article
Identification of Proteolytic Cleavage Sites by Quantitative Proteomics
Enoksson, Mari, Li, Jingwei, Ivancic, Melanie M, Timmer, John C, Wildfang, Eric, Eroshkin, Alexey, Salvesen, Guy S, Tao, W. Andy
Published in Journal of proteome research (01.07.2007)
Published in Journal of proteome research (01.07.2007)
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Journal Article
Notochord-derived BMP antagonists inhibit endothelial cell generation and network formation
Bressan, Michael, Davis, Patricia, Timmer, John, Herzlinger, Doris, Mikawa, Takashi
Published in Developmental biology (01.02.2009)
Published in Developmental biology (01.02.2009)
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Journal Article
12 Key pharmacokinetic and pharmacodynamic parameters that correlate with the anti-tumor activity of a bispecific PD-L1 conditional 4–1BB agonist
Kinkead, Heather, Macedo, Chelsie, Sanabria, Angelica, Cyprus, Garrett, Pandit, Rajay, Kalabus, James, Becklund, Bryan, Sulzmaier, Florian, Timmer, John, Deveraux, Quinn, Eckelman, Brendan, Heidt, Analeah
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Analysis of Mouse Embryonic Patterning and Morphogenesis by Forward Genetics
García-García, María J., Eggenschwiler, Jonathan T., Caspary, Tamara, Alcorn, Heather L., Wyler, Michael R., Huangfu, Danwei, Rakeman, Andrew S., Lee, Jeffrey D., Feinberg, Evan H., Timmer, John R., Anderson, Kathryn V.
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2005)
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Journal Article
856 INBRX-106: a novel hexavalent anti-OX40 agonist for the treatment of solid tumors
Rowell, Emily, Kinkead, Heather, Torretti, Elisabeth, Becklund, Bryan, Sulzmaier, Florian, Crago, William, Jones, Kyle, Timmer, John, Deveraux, Quinn, Eckelman, Brendan, Heidt, Analeah
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
722 INBRX-121 is an NKp46-targeted detuned IL-2 with antitumor activity as a monotherapy or in combination with multiple cancer immunotherapy modalities
Sulzmaier, Florian, Kinkead, Heather, Polovina, Anya, Kern, Nadja, Sanabria, Angelica, Macedo, Chelsie, Hussain, Abrahim, Ahn, Sae Jeong, Pandit, Rajay, Crago, William, Timmer, John, Heidt, Analeah, Eckelman, Brendan
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Tissue Morphogenesis and Vascular Stability Require the Frem2 Protein, Product of the Mouse Myelencephalic Blebs Gene
Timmer, John R., Mak, Tracy W., Manova, Katia, Anderson, Kathryn V., Niswander, Lee
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2005)
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Journal Article
Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation
Ebert, Philip J, Timmer, John R, Nakada, Yuji, Helms, Amy W, Parab, Preeti B, Liu, Ying, Hunsaker, Thomas L, Johnson, Jane E
Published in Development (Cambridge) (01.05.2003)
Published in Development (Cambridge) (01.05.2003)
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Journal Article
The use of in ovo electroporation for the rapid analysis of neural-specific murine enhancers
Timmer, John, Johnson, Jane, Niswander, Lee
Published in Genesis (New York, N.Y. : 2000) (01.03.2001)
Published in Genesis (New York, N.Y. : 2000) (01.03.2001)
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Journal Article
Recruitment of the Proneural Gene scute to the Drosophila Sex-Determination Pathway
Wrischnik, Lisa A, Timmer, John R, Megna, Lisa A, Cline, Thomas W
Published in Genetics (Austin) (01.12.2003)
Published in Genetics (Austin) (01.12.2003)
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Journal Article
An extracellular activator of the Drosophila JAK/STAT pathway is a sex-determination signal element
Cline, Thomas W, Sefton, Louise, Timmer, John R, Zhang, Yan, Béranger, Florence
Published in Nature (London) (22.06.2000)
Published in Nature (London) (22.06.2000)
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Journal Article
N-terminomics: a high-content screen for protease substrates and their cleavage sites
Timmer, John C, Salvesen, Guy S
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
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