Simultaneous quantification of abemaciclib and its active metabolites in human and mouse plasma by UHPLC–MS/MS
Martínez-Chávez, Alejandra, Tibben, Matthijs M., de Jong, Karen A.M., Rosing, Hilde, Schinkel, Alfred H., Beijnen, Jos H.
Published in Journal of pharmaceutical and biomedical analysis (05.09.2021)
Published in Journal of pharmaceutical and biomedical analysis (05.09.2021)
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Development and validation of an LC-MS/MS method for the quantitative analysis of milciclib in human and mouse plasma, mouse tissue homogenates and tissue culture medium
Martínez-Chávez, Alejandra, Tibben, Matthijs M., Broeders, Jelle, Rosing, Hilde, Schinkel, Alfred H., Beijnen, Jos H.
Published in Journal of pharmaceutical and biomedical analysis (25.10.2020)
Published in Journal of pharmaceutical and biomedical analysis (25.10.2020)
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ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
Martínez-Chávez, Alejandra, Loos, Nancy H.C., Lebre, Maria C., Tibben, Matthijs M., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
Published in Pharmacological research (01.04.2022)
Published in Pharmacological research (01.04.2022)
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A sensitive assay for the quantitative analysis of vinorelbine in mouse and human EDTA plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry
Damen, Carola W.N., Rosing, Hilde, Tibben, Matthijs M., van Maanen, Maria J., Lagas, Jurjen S., Schinkel, Alfred H., Schellens, Jan H.M., Beijnen, Jos H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2008)
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Development and validation of a combined liquid chromatography tandem-mass spectrometry assay for the quantification of aprepitant and dexamethasone in human plasma to support pharmacokinetic studies in pediatric patients
Nijstad, A. Laura, Tibben, Matthijs M., Gebretensae, Abadi, Rosing, Hilde, de Vos-Kerkhof, Evelien, Zwaan, C. Michel, Huitema, Alwin D.R., Beijnen, Jos H.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2021)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.05.2021)
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Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting
Nijstad, A. Laura, de Vos-Kerkhof, Evelien, Enters-Weijnen, Catherine F., van de Wetering, Marianne D., Tissing, Wim J. E., Tibben, Matthijs M., Rosing, Hilde, Lalmohamed, Arief, Huitema, Alwin D. R., Zwaan, C. Michel
Published in Supportive care in cancer (01.12.2022)
Published in Supportive care in cancer (01.12.2022)
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A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children
Nijstad, A Laura, de Vos-Kerkhof, Evelien, Enters-Weijnen, Catherine F, van de Wetering, Marianne D, Tissing, Wim J E, Hanff, Lidwien M, Lange, Rogier, Tibben, Matthijs M, Rosing, Hilde, Lalmohamed, Arief, Zwaan, C Michel, Huitema, Alwin D R
Published in Journal of oncology pharmacy practice (01.06.2023)
Published in Journal of oncology pharmacy practice (01.06.2023)
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Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: Potential role for breast cancer resistance protein in clinical drug-drug interactions
BREEDVELD, Pauline, ZELCER, Noam, PLUIM, Dick, SÖNMEZER, Özgür, TIBBEN, Matthijs M, BEIJNEN, Jos H, SCHINKEL, Alfred H, VAN TELLINGEN, Olaf, BORST, Piet, SCHELLENS, Jan H. M
Published in Cancer research (Chicago, Ill.) (15.08.2004)
Published in Cancer research (Chicago, Ill.) (15.08.2004)
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A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine
Jacobs, Bart A.W., Meulenaar, Jelte, Rosing, Hilde, Pluim, Dick, Tibben, Matthijs M., de Vries, Niels, Nuijen, Bastiaan, Huitema, Alwin D.R., Beijnen, Jos H., Schellens, Jan H.M., Marchetti, Serena
Published in Cancer chemotherapy and pharmacology (01.06.2016)
Published in Cancer chemotherapy and pharmacology (01.06.2016)
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Population pharmacokinetics of thioTEPA and its active metabolite TEPA in patients undergoing high‐dose chemotherapy
Huitema, Alwin D. R., Mathôt, Ron A. A., Tibben, Matthijs M., Schellens, Jan H. M., Rodenhuis, Sjoerd, Beijnen, Jos H.
Published in British journal of clinical pharmacology (01.01.2001)
Published in British journal of clinical pharmacology (01.01.2001)
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Determination of ruthenium originating from the investigational anti-cancer drug NAMI-A in human plasma ultrafiltrate, plasma, and urine by inductively coupled plasma mass spectrometry
Brouwers, Elke E. M., Tibben, Matthijs M., Rosing, Hilde, Schellens, Jan H. M., Beijnen, Jos H.
Published in Rapid communications in mass spectrometry (01.01.2007)
Published in Rapid communications in mass spectrometry (01.01.2007)
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Phase I and pharmacokinetic study of SPI-77, a liposomal encapsulated dosage form of cisplatin
TERWOGT, Jetske M, GROENEWEGEN, Gerard, BEIJNEN, Jos H, SCHELLENS, Jan H. M, PLUIM, Dick, MALIEPAARD, Marc, TIBBEN, Matthijs M, HUISMAN, Albert, TEN BOKKEL HUININK, Wim W, SCHOT, Margaret, WELBANK, Helen, VOEST, Emile E
Published in Cancer chemotherapy and pharmacology (01.03.2002)
Published in Cancer chemotherapy and pharmacology (01.03.2002)
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Mechanism of the Pharmacokinetic Interaction between Methotrexate and Benzimidazoles
Breedveld, Pauline, Zelcer, Noam, Pluim, Dick, Sönmezer, Özgür, Tibben, Matthijs M., Beijnen, Jos H., Schinkel, Alfred H., van Tellingen, Olaf, Borst, Piet, Schellens, Jan H. M.
Published in Cancer research (Chicago, Ill.) (15.08.2004)
Published in Cancer research (Chicago, Ill.) (15.08.2004)
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Abstract 6322: The role of multidrug efflux transporters and CYP3A in the pharmacokinetics and tissue distribution of abemaciclib and its active metabolites
Chavez, Alejandra Martinez, Tibben, Matthijs M., Lebre, Maria C., Rosing, Hilde, Beijnen, Jos H., Schinkel, Alfred H.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Quantitative analysis of D-24851, a novel anticancer agent, in human plasma and urine by liquid chromatography coupled with tandem mass spectrometry
Stokvis, Ellen, Nan-Offeringa, Lianda G. A. H., Ouwehand, Mariët, Tibben, Matthijs M., Rosing, Hilde, Schnaars, Yvonne, Grigat, Martina, Romeis, Peter, Schellens, Jan H. M., Beijnen, Jos H.
Published in Rapid communications in mass spectrometry (01.01.2004)
Published in Rapid communications in mass spectrometry (01.01.2004)
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Validation of a therapeutic drug monitoring strategy for thiotepa in a high-dose chemotherapy regimen
Huitema, A D, Mathôt, R A, Tibben, M M, Rodenhuis, S, Beijnen, J H
Published in Therapeutic drug monitoring (01.12.2001)
Published in Therapeutic drug monitoring (01.12.2001)
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Simple and selective determination of the cyclophosphamide metabolite phosphoramide mustard in human plasma using high-performance liquid chromatography
Huitema, Alwin D.R, Tibben, Matthijs M, Kerbusch, Thomas, Jantien Kettenes-van den Bosch, J, Rodenhuis, Sjoerd, Beijnen, Jos H
Published in Journal of chromatography. B, Biomedical sciences and applications (18.08.2000)
Published in Journal of chromatography. B, Biomedical sciences and applications (18.08.2000)
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Sensitive gas chromatographic determination of the cyclophosphamide metabolite 2-dechloroethylcyclophosphamide in human plasma
Huitema, Alwin D.R., Reinders, Cindy, Tibben, Matthijs M., Rodenhuis, Sjoerd, Beijnen, Jos H.
Published in Journal of chromatography. B, Biomedical sciences and applications (15.06.2001)
Published in Journal of chromatography. B, Biomedical sciences and applications (15.06.2001)
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