Impaired TFEB-Mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-Induced Liver Injury and Steatosis in Mice
Chao, Xiaojuan, Wang, Shaogui, Zhao, Katrina, Li, Yuan, Williams, Jessica A., Li, Tiangang, Chavan, Hemantkumar, Krishnamurthy, Partha, He, Xi C., Li, Linheng, Ballabio, Andrea, Ni, Hong-Min, Ding, Wen-Xing
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2018)
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An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
Wang, Yifeng, Gunewardena, Sumedha, Li, Feng, Matye, David J., Chen, Cheng, Chao, Xiaojuan, Jung, Taeyoon, Zhang, Yuxia, Czerwiński, Maciej, Ni, Hong-Min, Ding, Wen-Xing, Li, Tiangang
Published in Nature communications (17.07.2020)
Published in Nature communications (17.07.2020)
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Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice
Qi, Yunpeng, Jiang, Changtao, Cheng, Jie, Krausz, Kristopher W., Li, Tiangang, Ferrell, Jessica M., Gonzalez, Frank J., Chiang, John Y.L.
Published in Biochimica et biophysica acta (01.01.2015)
Published in Biochimica et biophysica acta (01.01.2015)
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Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation
Ma, Xiaowen, Chen, Allen, Melo, Luma, Clemente-Sanchez, Ana, Chao, Xiaojuan, Ahmadi, Ali Reza, Peiffer, Brandon, Sun, Zhaoli, Sesaki, Hiromi, Li, Tiangang, Wang, Xiaokun, Liu, Wanqing, Bataller, Ramon, Ni, Hong-Min, Ding, Wen-Xing
Published in Hepatology (Baltimore, Md.) (01.01.2023)
Published in Hepatology (Baltimore, Md.) (01.01.2023)
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Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)–Mixed Lineage Kinase Domain-Like Protein (MLKL)–Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers
Ni, Hong-Min, Chao, Xiaojuan, Kaseff, Joshua, Deng, Fengyan, Wang, Shaogui, Shi, Ying-Hong, Li, Tiangang, Ding, Wen-Xing, Jaeschke, Hartmut
Published in The American journal of pathology (01.07.2019)
Published in The American journal of pathology (01.07.2019)
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Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice
Hasan, Mohammad Nazmul, Chen, Jianglei, Matye, David, Wang, Huaiwen, Luo, Wenyi, Gu, Lijie, Clayton, Yung Dai, Du, Yanhong, Li, Tiangang
Published in Journal of lipid research (01.03.2023)
Published in Journal of lipid research (01.03.2023)
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Transgenic expression of cholesterol 7α‐hydroxylase in the liver prevents high‐fat diet–induced obesity and insulin resistance in mice
Li, Tiangang, Owsley, Erika, Matozel, Michelle, Hsu, Peter, Novak, Colleen M., Chiang, John Y. L.
Published in Hepatology (Baltimore, Md.) (01.08.2010)
Published in Hepatology (Baltimore, Md.) (01.08.2010)
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Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice
Hasan, Mohammad Nazmul, Wang, Huaiwen, Luo, Wenyi, Clayton, Yung Dai, Gu, Lijie, Du, Yanhong, Palle, Sirish K., Chen, Jianglei, Li, Tiangang
Published in Journal of lipid research (01.10.2024)
Published in Journal of lipid research (01.10.2024)
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Journal Article
Hepatic Autophagy Deficiency Compromises Farnesoid X Receptor Functionality and Causes Cholestatic Injury
Khambu, Bilon, Li, Tiangang, Yan, Shengmin, Yu, Changshun, Chen, Xiaoyun, Goheen, Michael, Li, Yong, Lin, Jingmei, Cummings, Oscar W., Lee, Youngmin A., Friedman, Scott, Dong, Zheng, Feng, Gen‐Sheng, Wu, Shangwei, Yin, Xiao‐Ming
Published in Hepatology (Baltimore, Md.) (01.05.2019)
Published in Hepatology (Baltimore, Md.) (01.05.2019)
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Overexpression of cholesterol 7α‐hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis
Li, Tiangang, Matozel, Michelle, Boehme, Shannon, Kong, Bo, Nilsson, Lisa‐Mari, Guo, Grace, Ellis, Ewa, Chiang, John Y. L.
Published in Hepatology (Baltimore, Md.) (01.03.2011)
Published in Hepatology (Baltimore, Md.) (01.03.2011)
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TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis
Matye, David, Gunewardena, Sumedha, Chen, Jianglei, Wang, Huaiwen, Wang, Yifeng, Hasan, Mohammad Nazmul, Gu, Lijie, Clayton, Yung Dai, Du, Yanhong, Chen, Cheng, Friedman, Jacob E., Lu, Shelly C., Ding, Wen-Xing, Li, Tiangang
Published in Nature communications (28.09.2022)
Published in Nature communications (28.09.2022)
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