Clinical Pharmacokinetic and Pharmacodynamic Overview of Nilotinib, a Selective Tyrosine Kinase Inhibitor
Tian, Xianbin, Zhang, Hefei, Heimbach, Tycho, He, Handan, Buchbinder, Aby, Aghoghovbia, Mary, Hourcade‐Potelleret, Florence
Published in Journal of clinical pharmacology (01.12.2018)
Published in Journal of clinical pharmacology (01.12.2018)
Get full text
Journal Article
Disposition of asciminib, a potent BCR-ABL1 tyrosine kinase inhibitor, in healthy male subjects
Tran, Phi, Hanna, Imad, Eggimann, Fabian Kurt, Schoepfer, Joseph, Ray, Tapan, Zhu, Bing, Wang, Lai, Priess, Petra, Tian, Xianbin, Hourcade-Potelleret, Florence, Einolf, Heidi J.
Published in Xenobiotica (01.02.2020)
Published in Xenobiotica (01.02.2020)
Get full text
Journal Article
ARC15105 Is a Potent Antagonist of Von Willebrand Factor Mediated Platelet Activation and Adhesion
Siller-Matula, Jolanta M, Merhi, Yahye, Tanguay, Jean-François, Duerschmied, Daniel, Wagner, Denisa D, McGinness, Kathleen E, Pendergrast, P Shannon, Chung, Jou-Ku, Tian, Xianbin, Schaub, Robert G, Jilma, Bernd
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.04.2012)
Get full text
Journal Article
A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer
Reynolds, Kerry Lynn, Bedard, Philippe L, Lee, Se-Hoon, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, Baselga, José, Blumenschein, Jr, George, Graham, Donna M, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Seroutou, Abdelkader, Tian, Xianbin, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Ramkumar, Thiruvamoor, Zubel, Angela, Bang, Yung-Jue
Published in BMC cancer (12.09.2017)
Published in BMC cancer (12.09.2017)
Get full text
Journal Article
Efficacious 11β-Hydroxysteroid Dehydrogenase Type I Inhibitors in the Diet-Induced Obesity Mouse Model
Wan, Zhao-Kui, Chenail, Eva, Xiang, Jason, Li, Huan-Qiu, Ipek, Manus, Bard, Joel, Svenson, Kristine, Mansour, Tarek S, Xu, Xin, Tian, Xianbin, Suri, Vipin, Hahm, Seung, Xing, Yuzhe, Johnson, Christian E, Li, Xiangping, Qadri, Ariful, Panza, Darrell, Perreault, Mylene, Tobin, James F, Saiah, Eddine
Published in Journal of medicinal chemistry (10.09.2009)
Published in Journal of medicinal chemistry (10.09.2009)
Get full text
Journal Article
The Important Role of Bcrp (Abcg2) in the Biliary Excretion of Sulfate and Glucuronide Metabolites of Acetaminophen, 4-Methylumbelliferone, and Harmol in Mice
Zamek-Gliszczynski, Maciej J, Nezasa, Ken-Ichi, Tian, Xianbin, Kalvass, J Cory, Patel, Nita J, Raub, Thomas J, Brouwer, Kim L R
Published in Molecular pharmacology (01.12.2006)
Published in Molecular pharmacology (01.12.2006)
Get full text
Journal Article
Differential Involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in Biliary Excretion of 4-Methylumbelliferyl Glucuronide and Sulfate in the Rat
Zamek-Gliszczynski, Maciej J, Hoffmaster, Keith A, Humphreys, Joan E, Tian, Xianbin, Nezasa, Ken-Ichi, Brouwer, Kim L R
Published in The Journal of pharmacology and experimental therapeutics (01.10.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2006)
Get full text
Journal Article
Ritonavir, Saquinavir, and Efavirenz, but Not Nevirapine, Inhibit Bile Acid Transport in Human and Rat Hepatocytes
McRae, Mary Peace, Lowe, Carolina M, Tian, Xianbin, Bourdet, David L, Ho, Richard H, Leake, Brenda F, Kim, Richard B, Brouwer, Kim L R, Kashuba, Angela D M
Published in The Journal of pharmacology and experimental therapeutics (01.09.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2006)
Get full text
Journal Article
Role of Glycosylation in Trafficking of Mrp2 in Sandwich-Cultured Rat Hepatocytes
Zhang, Peijin, Tian, Xianbin, Chandra, Priyamvada, Brouwer, Kim L R
Published in Molecular pharmacology (01.04.2005)
Published in Molecular pharmacology (01.04.2005)
Get full text
Journal Article
Impact of Basolateral Multidrug Resistance-Associated Protein (Mrp) 3 and Mrp4 on the Hepatobiliary Disposition of Fexofenadine in Perfused Mouse Livers
XIANBIN TIAN, SWIFT, Brandon, ZAMEK-GLISZCZYNSKI, Maciej J, BELINSKY, Martin G, KRUH, Gary D, BROUWER, Kim L. R
Published in Drug metabolism and disposition (01.05.2008)
Published in Drug metabolism and disposition (01.05.2008)
Get full text
Journal Article
Multidrug Resistance-Associated Protein 2 Is Primarily Responsible for the Biliary Excretion of Fexofenadine in Mice
XIANBIN TIAN, ZAMEK-GLISZCZYNSKI, Maciej J, JUN LI, BRIDGES, Arlene S, NEZASA, Ken-Ichi, PATEL, Nita J, RAUB, Thomas J, BROUWER, Kim L. R
Published in Drug metabolism and disposition (01.01.2008)
Published in Drug metabolism and disposition (01.01.2008)
Get full text
Journal Article
Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice
NEZASA, Ken-Ichi, XIANBIN TIAN, ZAMEK-GLISZCZYNSKI, Maciej J, PATEL, Nita J, RAUB, Thomas J, BROUWER, Kim L. R
Published in Drug metabolism and disposition (01.04.2006)
Published in Drug metabolism and disposition (01.04.2006)
Get full text
Journal Article
Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes
Wan, Zhao-Kui, Chenail, Eva, Li, Huan-Qiu, Ipek, Manus, Xiang, Jason, Suri, Vipin, Hahm, Seung, Bard, Joel, Svenson, Kristine, Xu, Xin, Tian, Xianbin, Wang, Mengmeng, Li, Xiangping, Johnson, Christian E, Qadri, Ariful, Panza, Darrell, Perreault, Mylene, Mansour, Tarek S, Tobin, James F, Saiah, Eddine
Published in ACS medicinal chemistry letters (10.01.2013)
Published in ACS medicinal chemistry letters (10.01.2013)
Get full text
Journal Article
Roles of P-Glycoprotein, Bcrp, and Mrp2 in Biliary Excretion of Spiramycin in Mice
XIANBIN TIAN, JUN LI, ZAMEK-GLISZCZYNSKI, Maciej J, BRIDGES, Arlene S, PEIJIN ZHANG, PATEL, Nita J, RAUB, Thomas J, POLLACK, Gary M, BROUWER, Kim L. R
Published in Antimicrobial Agents and Chemotherapy (01.09.2007)
Published in Antimicrobial Agents and Chemotherapy (01.09.2007)
Get full text
Journal Article
MULTIPLE MECHANISMS ARE INVOLVED IN THE BILIARY EXCRETION OF ACETAMINOPHEN SULFATE IN THE RAT: ROLE OF MRP2 AND BCRP1
Zamek-Gliszczynski, Maciej J, Hoffmaster, Keith A, Tian, Xianbin, Zhao, Rong, Polli, Joseph W, Humphreys, Joan E, Webster, Lindsey O, Bridges, Arlene S, Kalvass, J Cory, Brouwer, Kim L R
Published in Drug metabolism and disposition (01.08.2005)
Published in Drug metabolism and disposition (01.08.2005)
Get full text
Journal Article
The Contribution of Intestinal UDP-Glucuronosyltransferases in Modulating 7-Ethyl-10-hydroxy-camptothecin (SN-38)-Induced Gastrointestinal Toxicity in Rats
Tallman, Melanie N, Miles, Kristini K, Kessler, Fay K, Nielsen, Judith N, Tian, Xianbin, Ritter, Joseph K, Smith, Philip C
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2007)
Get full text
Journal Article