Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing
Winson, Michael K, Swift, Simon, Fish, Leigh, Throup, John P, Jørgensen, Frieda, Chhabra, Siri Ram, Bycroft, Barrie W, Williams, Paul, Stewart, Gordon S.A.B
Published in FEMS microbiology letters (15.06.1998)
Published in FEMS microbiology letters (15.06.1998)
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A genomic analysis of two‐component signal transduction in Streptococcus pneumoniae
Throup, John P., Koretke, Kristin K., Bryant, Alexander P., Ingraham, Karen A., Chalker, Alison F., Ge, Yigong, Marra, Andrea, Wallis, Nicola G., Brown, James R., Holmes, David J., Rosenberg, Martin, Burnham, Martin K. R.
Published in Molecular microbiology (01.02.2000)
Published in Molecular microbiology (01.02.2000)
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Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma
Portnoy, Alison, Kumar, Sanjay, Behm, David J, Mahar, Kelly M, Noble, Robert B, Throup, John P, Russ, Steven F
Published in Frontiers in pharmacology (01.01.2013)
Published in Frontiers in pharmacology (01.01.2013)
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The srhSR Gene Pair from Staphylococcus aureus: Genomic and Proteomic Approaches to the Identification and Characterization of Gene Function
Throup, John P, Zappacosta, Francesca, Lunsford, R. Dwayne, Annan, Roland S, Carr, Steven A, Lonsdale, John T, Bryant, Alexander P, McDevitt, Damien, Rosenberg, Martin, Burnham, Martin K. R
Published in Biochemistry (Easton) (28.08.2001)
Published in Biochemistry (Easton) (28.08.2001)
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Plants genetically modified to produce N-acylhomoserine lactones communicate with bacteria
Fray, R.G, Throup, J.P, Daykin, M, Wallace, A, Williams, P, Stewart, G.S.A.B, Grierson, D
Published in Nature biotechnology (01.10.1999)
Published in Nature biotechnology (01.10.1999)
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Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, placebo-controlled phase 3 POETYK PSO-1 trial
Armstrong, April W., Gooderham, Melinda, Warren, Richard B., Papp, Kim A., Strober, Bruce, Thaçi, Diamant, Morita, Akimichi, Szepietowski, Jacek C., Imafuku, Shinichi, Colston, Elizabeth, Throup, John, Kundu, Sudeep, Schoenfeld, Steve, Linaberry, Misti, Banerjee, Subhashis, Blauvelt, Andrew
Published in Journal of the American Academy of Dermatology (01.01.2023)
Published in Journal of the American Academy of Dermatology (01.01.2023)
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Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52-week, randomized, double-blinded, phase 3 Program fOr Evaluation of TYK2 inhibitor psoriasis second trial
Strober, Bruce, Thaçi, Diamant, Sofen, Howard, Kircik, Leon, Gordon, Kenneth B., Foley, Peter, Rich, Phoebe, Paul, Carle, Bagel, Jerry, Colston, Elizabeth, Throup, John, Kundu, Sudeep, Sekaran, Chitra, Linaberry, Misti, Banerjee, Subhashis, Papp, Kim A.
Published in Journal of the American Academy of Dermatology (01.01.2023)
Published in Journal of the American Academy of Dermatology (01.01.2023)
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Pharmacological inhibition of SLC6A19 lowers toxic phenylalanine burden in a PKU mouse model
Wobst, Heike, Viader, Andreu, van Kalken, Daniel, Cantin, Susan, Hollibaugh, Ryan, Pullen, Nicholas, Brown, Dean, Throup, John, Barrish, Joel
Published in Molecular genetics and metabolism (01.04.2024)
Published in Molecular genetics and metabolism (01.04.2024)
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Biochemical characterization of the first essential two-component signal transduction system from Staphylococcus aureus and Streptococcus pneumoniae
Clausen, Valerie A, Bae, Weonhye, Throup, John, Burnham, Martin K R, Rosenberg, Martin, Wallis, Nicola G
Published in Journal of molecular microbiology and biotechnology (01.01.2003)
Published in Journal of molecular microbiology and biotechnology (01.01.2003)
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Selectivity Profile of the Tyrosine Kinase 2 Inhibitor Deucravacitinib Compared with Janus Kinase 1/2/3 Inhibitors
Chimalakonda, Anjaneya, Burke, James, Cheng, Lihong, Catlett, Ian, Tagen, Michael, Zhao, Qihong, Patel, Aditya, Shen, Jun, Girgis, Ihab G., Banerjee, Subhashis, Throup, John
Published in Dermatology and therapy (01.10.2021)
Published in Dermatology and therapy (01.10.2021)
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JNT-517, a first-in-class SLC6A19 inhibitor for the treatment of phenylketonuria, enhances urinary excretion of phenylalanine in healthy volunteers
Viader, Andreu, Throup, John, Wobst, Heike, Blanchette, Heather, Nix, Darrell, Pullen, Nicholas, Brown, Dean, Barrish, Joel, Vaughn, Tobias, Weng, Haoling, Longo, Nicola, Harding, Cary
Published in Molecular genetics and metabolism (01.04.2024)
Published in Molecular genetics and metabolism (01.04.2024)
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34658 Deucravacitinib, an oral, selective tyrosine kinase 2 (TYK2) inhibitor, in patients with moderate to severe plaque psoriasis who had inadequate responses to apremilast at week 24 in the phase 3 POETYK PSO-1 and PSO-2 trials
Armstrong, April W., Warren, Richard B., Sofen, Howard, Spelman, Lynda, Leonardi, Craig, Banerjee, Subhashis, Wang, Tao, Throup, John, Colston, Elizabeth, Napoli, Andrew, Kimball, Alexa B.
Published in Journal of the American Academy of Dermatology (01.09.2022)
Published in Journal of the American Academy of Dermatology (01.09.2022)
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A SMALL MOLECULE SLC6A19 INHIBITOR INCREASES URINARY PHENYLALANINE EXCRETION AND REDUCES ITS PATHOGENIC PLASMA ACCUMULATION IN A PHENYLKETONURIA MOUSE MODEL
Wobst, Heike, Hollibaugh, Ryan, Muncipinto, Giovanni, Burkhart, Christopher, van Kalken, Daniel, Viader, Andreu, Blanchette, Heather, Brown, Dean, Pullen, Nick, Throup, John, Barrish, Joel
Published in Molecular genetics and metabolism (01.03.2023)
Published in Molecular genetics and metabolism (01.03.2023)
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Treatment of plaque psoriasis with deucravacitinib (POETYK PSO-2 study): a plain language summary
Strober, Bruce, Thaçi, Diamant, Sofen, Howard, Kircik, Leon, Gordon, Kenneth B, Foley, Peter, Rich, Phoebe, Paul, Carle, Bagel, Jerry, Colston, Elizabeth, Throup, John, Kundu, Sudeep, Sekaran, Chitra, Linaberry, Misti, Banerjee, Subhashis, Papp, Kim A
Published in Immunotherapy (01.08.2023)
Published in Immunotherapy (01.08.2023)
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Journal Article
Treatment of plaque psoriasis with deucravacitinib (POETYK PSO-1 study): a plain language summary
Armstrong, April W, Gooderham, Melinda, Warren, Richard B, Papp, Kim A, Strober, Bruce, Thaçi, Diamant, Morita, Akimichi, Szepietowski, Jacek C, Imafuku, Shinichi, Colston, Elizabeth, Throup, John, Kundu, Sudeep, Schoenfeld, Steve, Linaberry, Misti, Banerjee, Subhashis, Blauvelt, Andrew
Published in Immunotherapy (01.08.2023)
Published in Immunotherapy (01.08.2023)
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Deucravacitinib Improves Psoriasis Symptoms and Signs Diary Domain Scores in Patients With Moderate to Severe Plaque Psoriasis: Results From the Phase 3 POETYK PSO-1 and POETYK PSO-2 Studies
Armstrong, April, Strober, Bruce, Gordon, Kenneth, Zhuo, Joe, Becker, Brandon, Kisa, Renata, Throup, John, Kim, Jonghyeon, Papp, Kim
Published in Skin (Milwood, N.Y.) (05.11.2021)
Published in Skin (Milwood, N.Y.) (05.11.2021)
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Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 (TYK2) Inhibitor, Versus Placebo and Apremilast in Moderate to Severe Plaque Psoriasis: Onset of Action in the Phase 3 POETYK PSO-1 and POETYK PSO-2 Trials
Korman, Neil, Papp, Kim, Bagel, Jerry, Foley, Peter, Morita, Akimichi, Banerjee, Subhashis, Colston, Elizabeth, Wang, Tao, Throup, John, Thaci, Diamant
Published in Skin (Milwood, N.Y.) (05.11.2021)
Published in Skin (Milwood, N.Y.) (05.11.2021)
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Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 (TYK2) Inhibitor, Compared With Placebo and Apremilast in Moderate to Severe Psoriasis: Integrated Laboratory Parameter Results From the Phase 3 POETYK PSO-1 and POETYK PSO-2 Trials
Thaci, Diamant, Gordon, Kenneth, Gooderham, Melinda, Strober, Bruce, Korman, Neil, Banerjee, Subhashis, Colston, Elizabeth, Kim, Jonghyeon, Throup, John, Morita, Akimichi
Published in Skin (Milwood, N.Y.) (05.11.2021)
Published in Skin (Milwood, N.Y.) (05.11.2021)
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