Antibody Recognition of a Highly Conserved Influenza Virus Epitope
Ekiert, Damian C, Bhabha, Gira, Elsliger, Marc-André, Friesen, Robert H.E, Jongeneelen, Mandy, Throsby, Mark, Goudsmit, Jaap, Wilson, Ian A
Published in Science (American Association for the Advancement of Science) (10.04.2009)
Published in Science (American Association for the Advancement of Science) (10.04.2009)
Get full text
Journal Article
Sustained Inhibition of HER3 and EGFR Is Necessary to Induce Regression of HER2-Amplified Gastrointestinal Carcinomas
Leto, Simonetta M, Sassi, Francesco, Catalano, Irene, Torri, Valter, Migliardi, Giorgia, Zanella, Eugenia R, Throsby, Mark, Bertotti, Andrea, Trusolino, Livio
Published in Clinical cancer research (15.12.2015)
Published in Clinical cancer research (15.12.2015)
Get full text
Journal Article
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells
Throsby, Mark, van den Brink, Edward, Jongeneelen, Mandy, Poon, Leo L M, Alard, Philippe, Cornelissen, Lisette, Bakker, Arjen, Cox, Freek, van Deventer, Els, Guan, Yi, Cinatl, Jindrich, ter Meulen, Jan, Lasters, Ignace, Carsetti, Rita, Peiris, Malik, de Kruif, John, Goudsmit, Jaap
Published in PloS one (16.12.2008)
Published in PloS one (16.12.2008)
Get full text
Journal Article
A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade
Geuijen, Cecile, Tacken, Paul, Wang, Liang-Chuan, Klooster, Rinse, van Loo, Pieter Fokko, Zhou, Jing, Mondal, Arpita, Liu, Yao-bin, Kramer, Arjen, Condamine, Thomas, Volgina, Alla, Hendriks, Linda J. A., van der Maaden, Hans, Rovers, Eric, Engels, Steef, Fransen, Floris, den Blanken-Smit, Renate, Zondag-van der Zande, Vanessa, Basmeleh, Abdul, Bartelink, Willem, Kulkarni, Ashwini, Marissen, Wilfred, Huang, Cheng-Yen, Hall, Leslie, Harvey, Shane, Kim, Soyeon, Martinez, Marina, O’Brien, Shaun, Moon, Edmund, Albelda, Steven, Kanellopoulou, Chrysi, Stewart, Shaun, Nastri, Horacio, Bakker, Alexander B. H., Scherle, Peggy, Logtenberg, Ton, Hollis, Gregory, de Kruif, John, Huber, Reid, Mayes, Patrick A., Throsby, Mark
Published in Nature communications (21.07.2021)
Published in Nature communications (21.07.2021)
Get full text
Journal Article
common solution to group 2 influenza virus neutralization
Friesen, Robert H. E., Lee, Peter S., Stoop, Esther J. M., Hoffman, Ryan M. B., Ekiert, Damian C., Bhabha, Gira, Yu, Wenli, Juraszek, Jarek, Koudstaal, Wouter, Jongeneelen, Mandy, Korse, Hans J. W. M., Ophorst, Carla, Brinkman-van der Linden, Els C. M., Throsby, Mark, Kwakkenbos, Mark J., Bakker, Arjen Q., Beaumont, Tim, Spits, Hergen, Kwaks, Ted, Vogels, Ronald, Ward, Andrew B., Goudsmit, Jaap, Wilson, Ian A.
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
Get full text
Journal Article
Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose
de Vries Schultink, Aurelia H. M., Doornbos, Robert P., Bakker, Alexander B. H., Bol, Kees, Throsby, Mark, Geuijen, Cecile, Maussang, David, Schellens, Jan H. M., Beijnen, Jos H., Huitema, Alwin D. R.
Published in Investigational new drugs (01.12.2018)
Published in Investigational new drugs (01.12.2018)
Get full text
Journal Article
Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus
OLIPHANT, Theodore, NYBAKKEN, Grant E, KYLE AUSTIN, S, QING XU, BRAMSON, Jonathan, LOEB, Mark, THROSBY, Mark, FREMONT, Daved H, PIERSON, Theodore C, DIAMOND, Michael S
Published in Journal of Virology (01.11.2007)
Published in Journal of Virology (01.11.2007)
Get full text
Journal Article
Human Monoclonal Antibodies against West Nile Virus Induced by Natural Infection Neutralize at a Postattachment Step
VOGT, Matthew R, MOESKER, Bastiaan, DIAMOND, Michael S, GOUDSMIT, Jaap, JONGENEELEN, Mandy, KYLE AUSTIN, S, OLIPHANT, Theodore, NELSON, Steevenson, PIERSON, Theodore C, WILSCHUT, Jan, THROSBY, Mark
Published in Journal of Virology (01.07.2009)
Published in Journal of Virology (01.07.2009)
Get full text
Journal Article
Isolation and Characterization of Human Monoclonal Antibodies from Individuals Infected with West Nile Virus
THROSBY, Mark, GEUIJEN, Cecile, SMIT, Renate, VISSER, Therese J, BIJL, Nora, MARISSEN, Wilfred E, LOEB, Mark, KELVIN, David J, PREISER, Wolfgang, TER MEULEN, Jan, DE KRUIF, John, GOUDSMIT, Jaap, BAKKER, Arjen Q, KORIMBOCUS, Jehanara, ARJEN KRAMER, R, CLIJSTERS-VAN DER HORST, Marieke, DE JONG, Maureen, JONGENEELEN, Mandy, THIJSSE, Sandra
Published in Journal of Virology (01.07.2006)
Published in Journal of Virology (01.07.2006)
Get full text
Journal Article
814 MCLA-145 (CD137xPD-L1): a potent CD137 agonist and immune checkpoint inhibitor that that does not show signs of peripheral toxicity
Bol, Kees, Marissen, Wilfred, Elaissais-Schaap, Jeroen, Tacken, Paul, Engels, Steef, Wang, Liang-Chuan, Mondal, Arpita, Throsby, Mark, Roberts, Alan, Mayes, Patrick, Geuijen, Cecile
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
Get full text
Journal Article
A human monoclonal antibody cocktail as a novel component of rabies postexposure prophylaxis
de Kruif, John, Bakker, Alexander B H, Marissen, Wilfred E, Kramer, R Arjen, Throsby, Mark, Rupprecht, Charles E, Goudsmit, Jaap
Published in Annual review of medicine (01.01.2007)
Published in Annual review of medicine (01.01.2007)
Get more information
Journal Article
820 MCLA-145 is a bispecific IgG1 antibody that inhibits PD-1/PD-L1 signaling while simultaneously activating CD137 signaling on T cells
Tacken, Paul, Wang, Liang-chuan, Klooster, Rinse, Loo, Pieter Fokko Van, Zhou, Jing, Mondal, Arpita, Liu, Yao-Bin, Kramer, Arjen, Condamine, Thomas, Volgina, Alla, Hendriks, Linda, Maaden, Hans van der, Rovers, Eric, Engels, Steef, Fransen, Floris, Blanken-Smit, Renate den, Zande, Vanessa Zondag-van der, Basmeleh, Abdul, Bartelink, Willem, Kulkarni, Ashwini, Marissen, Wilfred, Huang, Cheng-Yen, Hall, Leslie, Harvey, Shane, Kanellopoulou, Chrysi, Stewart, Shaun, Nastri, Horacio, Bakker, Lex, Logtenberg, Ton, Plyte, Simon, Mayes, Patrick, Throsby, Mark, Geuijen, Cecile
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
Get full text
Journal Article
Novel Rabies Virus-Neutralizing Epitope Recognized by Human Monoclonal Antibody: Fine Mapping and Escape Mutant Analysis
MARISSEN, Wilfred E, ARJEN KRAMER, R, JONGENEELEN, Mandy, THIJSSE, Sandra, THROSBY, Mark, DE KRUIF, John, RUPPRECHT, Charles E, DIETZSCHOLD, Bernhard, GOUDSMIT, Jaap, BAKKER, Alexander B. H, RICE, Amy, WELDON, William C, NIEZGODA, Michael, FABER, Milosz, SLOOTSTRA, Jerry W, MELOEN, Rob H, CLIJSTERS-VAN DER HORST, Marieke, VISSER, Therese J
Published in Journal of Virology (01.04.2005)
Published in Journal of Virology (01.04.2005)
Get full text
Journal Article
Affinity ranking of antibodies using flow cytometry: Application in antibody phage display-based target discovery
Geuijen, Cecilia A.W., Clijsters-van der Horst, Marieke, Cox, Freek, Rood, Pauline M.L., Throsby, Mark, Jongeneelen, Mandy A.C., Backus, Harold H.J., van Deventer, Els, Kruisbeek, Ada M., Goudsmit, Jaap, de Kruif, John
Published in Journal of immunological methods (01.07.2005)
Published in Journal of immunological methods (01.07.2005)
Get full text
Journal Article