Commercial Synthesis of a Pyrrolotriazine–Fluoroindole Intermediate to Brivanib Alaninate: Process Development Directed toward Impurity Control
Pesti, Jaan A, LaPorte, Thomas, Thornton, John E, Spangler, Lori, Buono, Frederic, Crispino, Gerard, Gibson, Frank, Lobben, Paul, Papaioannou, Christos G
Published in Organic process research & development (17.01.2014)
Published in Organic process research & development (17.01.2014)
Get full text
Journal Article
Development of a Practical, Safe, and High-Yielding Process for the Preparation of Enantiomerically Pure trans-Cyclopropane Carboxylic Acid
Singh, Ambarish K, Rao, Meena N, Simpson, James H, Li, Wen-Sen, Thornton, John E, Kuehner, Daniel E, Kacsur, David J
Published in Organic process research & development (01.09.2002)
Published in Organic process research & development (01.09.2002)
Get full text
Journal Article
Correction to “Commercial Synthesis of a Pyrrolotriazine-Fluoroindole Intermediate to Brivanib Alaninate: Process Development Directed toward Impurity Control”
Pesti, Jaan A, LaPorte, Thomas, Thornton, John E, Spangler, Lori, Buono, Frederic, Crispino, Gerard, Gibson, Frank, Hamedi, Mourad, Lobben, Paul, Papaioannou, Christos G
Published in Organic process research & development (18.09.2015)
Published in Organic process research & development (18.09.2015)
Get full text
Journal Article
Development of Jacobsen Asymmetric Epoxidation and Sharpless Asymmetric Dihydroxylation Methods for the Large-Scale Preparation of a Chiral Dihydrobenzofuran Epoxide
Prasad, J. Siva, Vu, Truc, Totleben, Michael J, Crispino, Gerard A, Kacsur, David J, Swaminathan, Shankar, Thornton, John E, Fritz, Alan, Singh, Ambarish K
Published in Organic process research & development (01.11.2003)
Published in Organic process research & development (01.11.2003)
Get full text
Journal Article
PROCESS FOR THE PREPARATION OF Y(1R), 2S -2-AMINOPROPIONIC ACID 2-Y4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLOY2,1-f Y1,2,4 TRIAZIN-6-YLOXY -1-METHYLETHYL ESTER
LEAHY DAVID K, LOBBEN PAUL C, THORNTON JOHN E, MUSLEHIDDINOGLU JALE, HAMEDI MOURAD, XU ZHONGMIN, DISCORDIA ROBERT P, LAI CHIAJEN, CRISPINO GERARD A, PESTI JAAN A, SPANGLER LORI ANN, LAPORTE THOMAS L
Year of Publication 28.06.2013
Get full text
Year of Publication 28.06.2013
Patent
PROCESS FOR THE PREPARATION OF Ý(1R), 2S¨-2-AMINOPROPIONIC ACID 2-Ý4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLOÝ2,1-f¨Ý1,2,4¨TRIAZIN-6-YLOXY¨-1-METHYLETHYL ESTER
LAPORTE, THOMAS L, LEAHY, DAVID K, MUSLEHIDDINOGLU, JALE, LAI, CHIAJEN, CRISPINO, GERARD A, LOBBEN, PAUL C, DISCORDIA, ROBERT P, PESTI, JAAN A, HAMEDI, MOURAD, THORNTON, JOHN E, XU, ZHONGMIN, SPANGLER, LORI ANN
Year of Publication 30.04.2013
Get full text
Year of Publication 30.04.2013
Patent
PROCESS FOR THE PREPARATION OF [(1R), 2S]-2-AMINOPROPIONIC ACID 2-[4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLO]2,1-f-[1,2,4-TRIAZIN-6-YLOXY]-1-METHYLETHYL ESTER
LAPORTE, THOMAS L, LEAHY, DAVID K, MUSLEHIDDINOGLU, JALE, LAI, CHIAJEN, CRISPINO, GERARD A, LOBBEN, PAUL C, DISCORDIA, ROBERT P, PESTI, JAAN A, HAMEDI, MOURAD, THORNTON, JOHN E, XU, ZHONGMIN, SPANGLER, LORI ANN
Year of Publication 31.03.2013
Get full text
Year of Publication 31.03.2013
Patent
PROCESS FOR THE PREPARATION OF (1R), 2S -2-AMINOPROPIONIC ACID 2- 4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLO 2,1-F 1,2,4 TRIAZIN-6-YLOXY -1-METHYLETHYL ESTER
GERARD A. CRISPINO, THOMAS L. LAPORTE, JALE MUSLEHIDDINOGLU, PAUL C. LOBBEN, MOURAD HAMEDI, DAVID K. LEAHY, CHIAJEN LAI, ROBERT P. RDIA, JOHN E. THORNTON, ZHONGMIN XU, JAAN A. PESTI, LORI ANN GLER
Year of Publication 22.02.2013
Get full text
Year of Publication 22.02.2013
Patent
PROCESS FOR THE PREPARATION OF Ý(1R), 2S¨-2-AMINOPROPIONIC ACID 2-Ý4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLOÝ2,1-f¨Ý1,2,4¨TRIAZIN-6-YLOXY¨-1-METHYLETHYL ESTER
LAPORTE, THOMAS L, LEAHY, DAVID K, MUSLEHIDDINOGLU, JALE, LAI, CHIAJEN, CRISPINO, GERARD A, LOBBEN, PAUL C, DISCORDIA, ROBERT P, PESTI, JAAN A, HAMEDI, MOURAD, THORNTON, JOHN E, XU, ZHONGMIN, SPANGLER, LORI ANN
Year of Publication 05.12.2012
Get full text
Year of Publication 05.12.2012
Patent