A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice
Østergaard, Henrik, Lund, Jacob, Greisen, Per J., Kjellev, Stine, Henriksen, Anette, Lorenzen, Nikolai, Johansson, Eva, Røder, Gustav, Rasch, Morten G., Johnsen, Laust B., Egebjerg, Thomas, Lund, Søren, Rahbek-Nielsen, Henrik, Gandhi, Prafull S., Lamberth, Kasper, Loftager, Mette, Andersen, Lisbeth M., Bonde, Amalie C., Stavenuiter, Fabian, Madsen, Daniel E., Li, Xun, Holm, Thomas L., Ley, Carsten D., Thygesen, Peter, Zhu, Haisun, Zhou, Rong, Thorn, Karina, Yang, Zhiru, Hermit, Mette B., Bjelke, Jais R., Hansen, Bjarne G., Hilden, Ida
Published in Blood (07.10.2021)
Published in Blood (07.10.2021)
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Mim8 - a Next-Generation FVIII Mimetic Bi-Specific Antibody - Potently Restores the Hemostatic Capacity in Hemophilia a Settings in Vitro and In Vivo
Kjellev, Stine L, Østergaard, Henrik, Greisen, Per Jr, Hermit, Mette B, Thorn, Karina, Hansen, Bjarne G, Zhou, Rong, Bjelke, Jais Rose, Kjalke, Marianne, Lund, Jacob, Holm, Thomas L, Ley, Carsten Dan, Elenius, Daniel, Thygesen, Peter, Loftager, Mette, Rasch, Morten G, Lorenzen, Nikolai, Gandhi, Prafull S, Lamberth, Kasper, Egebjerg, Thomas, Lund, Søren, Henriksen, Anette, Rahbek-Nielsen, Henrik, Yang, Zhiru, Hilden, Ida
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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IMPROVED PROCOAGULANT ANTIBODIES
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Year of Publication 22.07.2021
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Year of Publication 22.07.2021
Patent
개선된 응혈 촉진 항체
JOHNSEN LAUST BRUUN, SVENSSON ANDERS, YANG ZHIRU, HANSEN BJARNE GRAM, ØSTERGAARD HENRIK, CHEN JIANHE, THORN KARINA, JOHANSSON EVA, GREISEN PER J, ZHU HAISUN, HARNDAHL MIKKEL NORS, ZHOU RONG, RASCH MORTEN GRØNBECH
Year of Publication 13.04.2021
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Year of Publication 13.04.2021
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The tandem chain extension aldol reaction used for synthesis of ketomethylene tripeptidomimetics targeting hPEPT1
Thorn, Karina, Nielsen, Carsten Uhd, Jakobsen, Palle, Steffansen, Bente, Zercher, Charles K., Begtrup, Mikael
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
Published in Bioorganic & medicinal chemistry letters (01.08.2011)
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응고촉진 항체
JOHNSEN LAUST BRUUN, SVENSSON ANDERS, YANG ZHIRU, HANSEN BJARNE GRAM, OSTERGAARD HENRIK, CHEN JIANHE, THORN KARINA, JOHANSSON EVA, GREISEN PER J, ZHU HAISUN, HARNDAHL MIKKEL NORS, RASCH MORTEN GRONBECH, ZHOU RONG
Year of Publication 07.10.2019
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Year of Publication 07.10.2019
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Design, Synthesis, and Evaluation of Tripeptidic Promoieties Targeting the Intestinal Peptide Transporter hPEPT1
Thorn, Karina, Andersen, Rikke, Christensen, Jon, Jakobsen, Palle, Nielsen, Carsten Uhd, Steffansen, Bente, Begtrup, Mikael
Published in ChemMedChem (16.04.2007)
Published in ChemMedChem (16.04.2007)
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Development of a QSAR model for binding of tripeptides and tripeptidomimetics to the human intestinal Di-/tripeptide transporter hPEPT1
ANDERSEN, Rikke, JØRGENSEN, Flenlnling Steen, OLSEN, Lars, VABENØ, Jon, THORN, Karina, NIELSEN, Carsten Uhd, STEFFANSEN, Bente
Published in Pharmaceutical research (01.03.2006)
Published in Pharmaceutical research (01.03.2006)
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FACTOR X BINDERS ENHANCING FX ACTIVATION
Steffensen, Soren, Harndahl, Mikkel Nors, De Tavernier, Evelyn, Lund, Jacob, Buyse, Marie-Ange, Thorn, Karina
Year of Publication 28.12.2023
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Year of Publication 28.12.2023
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Factor X binders enhancing FX activation
Steffensen, Soren, Harndahl, Mikkel Nors, De Tavernier, Evelyn, Lund, Jacob, Buyse, Marie-Ange, Thorn, Karina
Year of Publication 17.10.2023
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Year of Publication 17.10.2023
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Procoagulant antibodies
Zhu, Haisun, Oestergaard, Henrik, Yang, Zhiru, Harndahl, Mikkel Nors, Chen, Jianhe, Greisen, Per J, Rasch, Morten Groenbech, Zhou, Rong, Johnsen, Laust Bruun, Gandhi, Prafull S, Thorn, Karina, Hansen, Bjarne Gram
Year of Publication 10.09.2024
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Year of Publication 10.09.2024
Patent