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Estrogen blockade reduces auditory feedback in CBA mice
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Topical Application of ASN008, a Permanently-charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset and Long Duration of Action in a Mouse Model of Pruritus
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Discovery of Substituted Maleimides as Liver X Receptor Agonists and Determination of a Ligand-Bound Crystal Structure
Jaye, Michael C, Krawiec, John A, Campobasso, Nino, Smallwood, Angela, Qiu, Chunyan, Lu, Quinn, Kerrigan, John J, De Los Frailes Alvaro, Maite, Laffitte, Bryan, Liu, Wu-Schyong, Marino, Joseph P, Meyer, Craig R, Nichols, Jason A, Parks, Derek J, Perez, Paloma, Sarov-Blat, Lea, Seepersaud, Sheila D, Steplewski, Klaudia M, Thompson, Scott K, Wang, Ping, Watson, Mike A, Webb, Christine L, Haigh, David, Caravella, Justin A, Macphee, Colin H, Willson, Timothy M, Collins, Jon L
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Steady-State Kinetic Characterization of Substrates and Metal-Ion Specificities of the Full-Length and N-Terminally Truncated Recombinant Human Methionine Aminopeptidases (Type 2)
Yang, Guang, Kirkpatrick, Robert B, Ho, Thau, Zhang, Gui-Feng, Liang, Po-Huang, Johanson, Kyung O, Casper, David J, Doyle, Michael L, Marino, Joseph P, Thompson, Scott K, Chen, Wenfang, Tew, David G, Meek, Thomas D
Published in Biochemistry (Easton) (04.09.2001)
Published in Biochemistry (Easton) (04.09.2001)
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4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo
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Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore
Marino, Joseph P, Fisher, Paul W, Hofmann, Glenn A, Kirkpatrick, Robert B, Janson, Cheryl A, Johnson, Randall K, Ma, Chun, Mattern, Michael, Meek, Thomas D, Ryan, M. Dominic, Schulz, Christina, Smith, Ward W, Tew, David G, Tomazek, Thaddeus A, Veber, Daniel F, Xiong, Wenfang C, Yamamoto, Yuuichi, Yamashita, Keizo, Yang, Guang, Thompson, Scott K
Published in Journal of medicinal chemistry (09.08.2007)
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Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors
Hammond, Marlys, Washburn, David G., Hoang, Tram H., Manns, Sharada, Frazee, James S., Nakamura, Hiroko, Patterson, Jaclyn R., Trizna, Walter, Wu, Charlene, Azzarano, Leonard M., Nagilla, Rakesh, Nord, Melanie, Trejo, Rebecca, Head, Martha S., Zhao, Baoguang, Smallwood, Angela M., Hightower, Kendra, Laping, Nicholas J., Schnackenberg, Christine G., Thompson, Scott K.
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Rational Design, Synthesis, and Crystallographic Analysis of a Hydroxyethylene-Based HIV-1 Protease Inhibitor Containing a Heterocyclic P1'-P2' Amide Bond Isostere
Thompson, Scott K, Murthy, Krishna H. M, Zhao, Baoguang, Winborne, Evon, Green, David W, Fisher, Seth M, DesJarlais, Renee L, Tomaszek, Thaddeus A. Jr, Meek, Thomas D
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Synthesis and SAR of potent LXR agonists containing an indole pharmacophore
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Published in Bioorganic & medicinal chemistry letters (15.02.2009)
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Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists
Hammond, Marlys, Patterson, Jaclyn R., Manns, Sharada, Hoang, Tram H., Washburn, David G., Trizna, Walter, Glace, Lindsay, Grygielko, Eugene T., Nagilla, Rakesh, Nord, Melanie, Fries, Harvey E., Minick, Douglas J., Laping, Nicholas J., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
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Published in Bioorganic & medicinal chemistry letters (01.01.2010)
Published in Bioorganic & medicinal chemistry letters (01.01.2010)
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Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists
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Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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