The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Bouhaddou, Mehdi, Memon, Danish, Meyer, Bjoern, White, Kris M., Rezelj, Veronica V., Correa Marrero, Miguel, Polacco, Benjamin J., Melnyk, James E., Ulferts, Svenja, Kaake, Robyn M., Batra, Jyoti, Richards, Alicia L., Stevenson, Erica, Gordon, David E., Rojc, Ajda, Obernier, Kirsten, Fabius, Jacqueline M., Soucheray, Margaret, Miorin, Lisa, Moreno, Elena, Koh, Cassandra, Tran, Quang Dinh, Hardy, Alexandra, Robinot, Rémy, Vallet, Thomas, Nilsson-Payant, Benjamin E., Hernandez-Armenta, Claudia, Dunham, Alistair, Weigang, Sebastian, Knerr, Julian, Modak, Maya, Quintero, Diego, Zhou, Yuan, Dugourd, Aurelien, Valdeolivas, Alberto, Patil, Trupti, Li, Qiongyu, Hüttenhain, Ruth, Cakir, Merve, Muralidharan, Monita, Kim, Minkyu, Jang, Gwendolyn, Tutuncuoglu, Beril, Hiatt, Joseph, Guo, Jeffrey Z., Xu, Jiewei, Bouhaddou, Sophia, Mathy, Christopher J.P., Gaulton, Anna, Manners, Emma J., Félix, Eloy, Shi, Ying, Goff, Marisa, Lim, Jean K., McBride, Timothy, O’Neal, Michael C., Cai, Yiming, Chang, Jason C.J., Broadhurst, David J., Klippsten, Saker, De wit, Emmie, Leach, Andrew R., Kortemme, Tanja, Shoichet, Brian, Ott, Melanie, Saez-Rodriguez, Julio, tenOever, Benjamin R., Mullins, R. Dyche, Fischer, Elizabeth R., Kochs, Georg, Grosse, Robert, García-Sastre, Adolfo, Vignuzzi, Marco, Johnson, Jeffery R., Shokat, Kevan M., Swaney, Danielle L., Beltrao, Pedro, Krogan, Nevan J.
Published in Cell (06.08.2020)
Published in Cell (06.08.2020)
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Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
Tummino, Tia A, Rezelj, Veronica V, Fischer, Benoit, Fischer, Audrey, O'Meara, Matthew J, Monel, Blandine, Vallet, Thomas, White, Kris M, Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O'Donnell, Henry R, Lyu, Jiankun, Rosales, Romel, McGovern, Briana L, Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J, Urban, Laszlo, Shokat, Kevan M, Kruse, Andrew C, García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K
Published in Science (30.07.2021)
Published in Science (30.07.2021)
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Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects
Poirier, Enzo Z., Goic, Bertsy, Tomé-Poderti, Lorena, Frangeul, Lionel, Boussier, Jérémy, Gausson, Valérie, Blanc, Hervé, Vallet, Thomas, Loyd, Hyelee, Levi, Laura I., Lanciano, Sophie, Baron, Chloé, Merkling, Sarah H., Lambrechts, Louis, Mirouze, Marie, Carpenter, Susan, Vignuzzi, Marco, Saleh, Maria-Carla
Published in Cell host & microbe (14.03.2018)
Published in Cell host & microbe (14.03.2018)
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Host nutritional status affects alphavirus virulence, transmission, and evolution
Weger-Lucarelli, James, Carrau, Lucia, Levi, Laura I, Rezelj, Veronica, Vallet, Thomas, Blanc, Hervé, Boussier, Jérémy, Megrian, Daniela, Coutermarsh-Ott, Sheryl, LeRoith, Tanya, Vignuzzi, Marco
Published in PLoS pathogens (11.11.2019)
Published in PLoS pathogens (11.11.2019)
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Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes
Levi, Laura I, Rezelj, Veronica V, Henrion-Lacritick, Annabelle, Erazo, Diana, Boussier, J, Vallet, Thomas, Bernhauerová, Veronika, Suzuki, Yasutsugu, Carrau, Lucia, Weger-Lucarelli, James, Saleh, Maria-Carla, Vignuzzi, Marco
Published in PLoS pathogens (01.02.2021)
Published in PLoS pathogens (01.02.2021)
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Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen
Mac Kain, Alice, Maarifi, Ghizlane, Aicher, Sophie-Marie, Arhel, Nathalie, Baidaliuk, Artem, Munier, Sandie, Donati, Flora, Vallet, Thomas, Tran, Quang Dinh, Hardy, Alexandra, Chazal, Maxime, Porrot, Françoise, OhAinle, Molly, Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Zimmer, Gert, Simon-Lorière, Etienne, Bruel, Timothée, Schwartz, Olivier, van der Werf, Sylvie, Jouvenet, Nolwenn, Nisole, Sébastien, Vignuzzi, Marco, Roesch, Ferdinand
Published in Nature communications (04.05.2022)
Published in Nature communications (04.05.2022)
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Defective viral genomes as therapeutic interfering particles against flavivirus infection in mammalian and mosquito hosts
Rezelj, Veronica V., Carrau, Lucía, Merwaiss, Fernando, Levi, Laura I., Erazo, Diana, Tran, Quang Dinh, Henrion-Lacritick, Annabelle, Gausson, Valérie, Suzuki, Yasutsugu, Shengjuler, Djoshkun, Meyer, Bjoern, Vallet, Thomas, Weger-Lucarelli, James, Bernhauerová, Veronika, Titievsky, Avi, Sharov, Vadim, Pietropaoli, Stefano, Diaz-Salinas, Marco A., Legros, Vincent, Pardigon, Nathalie, Barba-Spaeth, Giovanna, Brodsky, Leonid, Saleh, Maria-Carla, Vignuzzi, Marco
Published in Nature communications (16.04.2021)
Published in Nature communications (16.04.2021)
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Chikungunya Virus Overcomes Polyamine Depletion by Mutation of nsP1 and the Opal Stop Codon To Confer Enhanced Replication and Fitness
Mounce, Bryan C, Cesaro, Teresa, Vlajnić, Lea, Vidiņa, Anna, Vallet, Thomas, Weger-Lucarelli, James, Passoni, Gabriella, Stapleford, Kenneth A, Levraud, Jean-Pierre, Vignuzzi, Marco
Published in Journal of virology (01.08.2017)
Published in Journal of virology (01.08.2017)
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The low-density lipoprotein receptor and apolipoprotein E associated with CCHFV particles mediate CCHFV entry into cells
Ritter, Maureen, Canus, Lola, Gautam, Anupriya, Vallet, Thomas, Zhong, Li, Lalande, Alexandre, Boson, Bertrand, Gandhi, Apoorv, Bodoirat, Sergueï, Burlaud-Gaillard, Julien, Freitas, Natalia, Roingeard, Philippe, Barr, John N., Lotteau, Vincent, Legros, Vincent, Mathieu, Cyrille, Cosset, François-Loïc, Denolly, Solène
Published in Nature communications (28.05.2024)
Published in Nature communications (28.05.2024)
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Development of iminosugar-based glycosidase inhibitors as drug candidates for SARS-CoV-2 virus via molecular modelling and in vitro studies
Ferjancic, Zorana, Bihelovic, Filip, Vulovic, Bojan, Matovic, Radomir, Trmcic, Milena, Jankovic, Aleksandar, Pavlovic, Milos, Djurkovic, Filip, Prodanovic, Radivoje, Djelmas, Aleksandra Djurdjevic, Kalicanin, Nevena, Zlatovic, Mario, Sladic, Dusan, Vallet, Thomas, Vignuzzi, Marco, Saicic, Radomir N.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2024)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2024)
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The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito
Cereghino, Chelsea, Roesch, Ferdinand, Carrau, Lucía, Hardy, Alexandra, Ribeiro-Filho, Helder V, Henrion-Lacritick, Annabelle, Koh, Cassandra, Marano, Jeffrey M, Bates, Tyler A, Rai, Pallavi, Chuong, Christina, Akter, Shamima, Vallet, Thomas, Blanc, Hervé, Elliott, Truitt J, Brown, Anne M, Michalak, Pawel, LeRoith, Tanya, Bloom, Jesse D, Marques, Rafael Elias, Saleh, Maria-Carla, Vignuzzi, Marco, Weger-Lucarelli, James
Published in PLoS pathogens (05.04.2023)
Published in PLoS pathogens (05.04.2023)
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Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genome Production
Levi, Laura I, Madden, Emily A, Boussier, Jeremy, Erazo, Diana, Sanders, Wes, Vallet, Thomas, Bernhauerova, Veronika, Moorman, Nathaniel J, Heise, Mark T, Vignuzzi, Marco
Published in Microorganisms (Basel) (29.08.2024)
Published in Microorganisms (Basel) (29.08.2024)
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Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding
Mounce, Bryan C., Cesaro, Teresa, Carrau, Lucia, Vallet, Thomas, Vignuzzi, Marco
Published in Antiviral research (01.06.2017)
Published in Antiviral research (01.06.2017)
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O'Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J P, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O'Neal, Michael C, Cai, Yiming, Chang, Jason C J, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia
Published in Nature (London) (16.07.2020)
Published in Nature (London) (16.07.2020)
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A virus‐derived microRNA targets immune response genes during SARS‐CoV‐2 infection
Singh, Meetali, Chazal, Maxime, Quarato, Piergiuseppe, Bourdon, Loan, Malabat, Christophe, Vallet, Thomas, Vignuzzi, Marco, van der Werf, Sylvie, Behillil, Sylvie, Donati, Flora, Sauvonnet, Nathalie, Nigro, Giulia, Bourgine, Maryline, Jouvenet, Nolwenn, Cecere, Germano
Published in EMBO reports (03.02.2022)
Published in EMBO reports (03.02.2022)
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Quantitative evaluation of PpSP15-LmSTI1 fusion gene expression following transfection with an alphavirus-derived self-amplifying mRNA and conventional DNA vaccine platforms
Savar, Nastaran Sadat, Vallet, Thomas, Azizi, Masoumeh, Arashkia, Arash, Lundstrom, Kenneth, Vignuzzi, Marco, Niknam, Hamid Mahmoudzadeh
Published in Molecular and cellular probes (01.10.2021)
Published in Molecular and cellular probes (01.10.2021)
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APOBEC3C S188I Polymorphism Enhances Context-Specific Editing of Hepatitis B Virus Genome
Khalfi, Pierre, Suspène, Rodolphe, Caval, Vincent, Thiers, Valérie, Beauclair, Guillaume, Marchio, Agnès, Bekondi, Claudine, Amougou Atsama, Marie, Camengo-Police, Serge Magloire, Noah Noah, Dominique, Njouom, Richard, Blanc, Hervé, Vallet, Thomas, Vignuzzi, Marco, Pineau, Pascal, Vartanian, Jean Pierre
Published in The Journal of infectious diseases (13.09.2022)
Published in The Journal of infectious diseases (13.09.2022)
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Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
Janissen, Richard, Woodman, Andrew, Shengjuler, Djoshkun, Vallet, Thomas, Lee, Kuo-Ming, Kuijpers, Louis, Moustafa, Ibrahim M., Fitzgerald, Fiona, Huang, Peng-Nien, Perkins, Angela L., Harki, Daniel A., Arnold, Jamie J., Solano, Belén, Shih, Shin-Ru, Vignuzzi, Marco, Cameron, Craig E., Dekker, Nynke H.
Published in Molecular cell (04.11.2021)
Published in Molecular cell (04.11.2021)
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An alphavirus-derived self-amplifying mRNA encoding PpSP15-LmSTI1 fusion protein for the design of a vaccine against leishmaniasis
Savar, Nastaran Sadat, Shengjuler, Djoshkun, Doroudian, Fatemeh, Vallet, Thomas, Mac Kain, Alice, Arashkia, Arash, Khamesipour, Ali, Lundstrom, Kenneth, Vignuzzi, Marco, Niknam, Hamid Mahmoudzadeh
Published in Parasitology international (01.08.2022)
Published in Parasitology international (01.08.2022)
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