Search Results - "THOMAS, Andrew W" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome

Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome

by Martínez-Cué, Carmen, Martínez, Paula, Rueda, Noemí, Vidal, Rebeca, García, Susana, Vidal, Verónica, Corrales, Andrea, Montero, Juan A, Pazos, Ángel, Flórez, Jesús, Gasser, Rodolfo, Thomas, Andrew W, Honer, Michael, Knoflach, Frédéric, Trejo, Jose Luis, Wettstein, Joseph G, Hernández, Maria-Clemencia
Published in The Journal of neuroscience (27.02.2013)

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Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man

Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man

by Hipp, Joerg F., Knoflach, Frederic, Comley, Robert, Ballard, Theresa M., Honer, Michael, Trube, Gerhard, Gasser, Rodolfo, Prinssen, Eric, Wallace, Tanya L., Rothfuss, Andreas, Knust, Henner, Lennon-Chrimes, Sian, Derks, Michael, Bentley, Darren, Squassante, Lisa, Nave, Stephane, Nöldeke, Jana, Wandel, Christoph, Thomas, Andrew W., Hernandez, Maria-Clemencia
Published in Scientific reports (08.04.2021)

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The Ability of Exercise-Associated Oxidative Stress to Trigger Redox-Sensitive Signalling Responses

The Ability of Exercise-Associated Oxidative Stress to Trigger Redox-Sensitive Signalling Responses

by Webb, Richard, Hughes, Michael G, Thomas, Andrew W, Morris, Keith
Published in Antioxidants (10.08.2017)

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Discovery of Small Molecule Therapeutics for Treatment of Chronic HBV Infection

Discovery of Small Molecule Therapeutics for Treatment of Chronic HBV Infection

by Feng, Song, Gao, Lu, Han, Xingchun, Hu, Taishan, Hu, Yimin, Liu, Haixia, Thomas, Andrew W, Yan, Zhipeng, Yang, Song, Young, John A. T, Yun, Hongying, Zhu, Wei, Shen, Hong C
Published in ACS infectious diseases (09.03.2018)

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Journal Article

Organic synthesis provides opportunities to transform drug discovery

Organic synthesis provides opportunities to transform drug discovery

by Blakemore, David C, Castro, Luis, Churcher, Ian, Rees, David C, Thomas, Andrew W, Wilson, David M, Wood, Anthony
Published in Nature chemistry (01.04.2018)

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Interleukin-6 and associated cytokine responses to an acute bout of high-intensity interval exercise: the effect of exercise intensity and volume

Interleukin-6 and associated cytokine responses to an acute bout of high-intensity interval exercise: the effect of exercise intensity and volume

by Cullen, Tom, Thomas, Andrew W, Webb, Richard, Hughes, Michael G
Published in Applied physiology, nutrition, and metabolism (01.08.2016)

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M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

M2 macrophages exhibit higher sensitivity to oxLDL-induced lipotoxicity than other monocyte/macrophage subtypes

by Isa, Suleiman A, Ruffino, José S, Ahluwalia, Maninder, Thomas, Andrew W, Morris, Keith, Webb, Richard
Published in Lipids in health and disease (06.12.2011)

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Modern Synthetic Methods for Copper-Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation

Modern Synthetic Methods for Copper-Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation

by Ley, Steven V., Thomas, Andrew W.
Published in Angewandte Chemie (International ed.) (17.11.2003)

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Discovery of the imidazo[1,5-α][1,2,4].triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series

Discovery of the imidazo[1,5-α][1,2,4].triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABAA α5 inverse agonist series

by ACHERMANN, Guido, BALLARD, Theresa M, KOBLET, Andreas, KNUST, Henner, KURT, Anke, MARTIN, James R, MASCIADRI, Raffaello, PORTER, Richard H. P, STADLER, Heinz, THOMAS, Andrew W, TRUBE, Gerhard, WICHMANN, Jürgen, BLASCO, Francesca, BROUTIN, Pierre-Emmanuel, BÜTTELMANN, Bernd, FISCHER, Holger, GRAF, Martin, HERNANDEZ, Maria-Clemencia, HILTY, Peter, KNOFLACH, Frédéric
Published in Bioorganic & medicinal chemistry letters (01.10.2009)

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Journal Article

sIL-6R Is Related to Weekly Training Mileage and Psychological Well-being in Athletes

sIL-6R Is Related to Weekly Training Mileage and Psychological Well-being in Athletes

by Cullen, Tom, Thomas, Andrew W, Webb, Richard, Phillips, Thom, Hughes, Michael G
Published in Medicine and science in sports and exercise (01.06.2017)

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Inhibition of alcohol self-administration by positive allosteric modulators of the GABAB receptor in rats: lack of tolerance and potentiation of baclofen

Inhibition of alcohol self-administration by positive allosteric modulators of the GABAB receptor in rats: lack of tolerance and potentiation of baclofen

by Maccioni, Paola, Vargiolu, Daniela, Thomas, Andrew W., Malherbe, Pari, Mugnaini, Claudia, Corelli, Federico, Leite-Morris, Kimberly A., Gessa, Gian Luigi, Colombo, Giancarlo
Published in Psychopharmacology (01.05.2015)

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Transposition of DEH, a Broad-Host-Range Transposon Flanked by ISPpu12, in Pseudomonas putida Is Associated with Genomic Rearrangements and Dehalogenase Gene Silencing

Transposition of DEH, a Broad-Host-Range Transposon Flanked by ISPpu12, in Pseudomonas putida Is Associated with Genomic Rearrangements and Dehalogenase Gene Silencing

by Weightman, Andrew J, Topping, Andrew W, Hill, Katja E, Lee, Li Ling, Sakai, Kenji, Slater, J Howard, Thomas, Andrew W
Published in Journal of Bacteriology (01.12.2002)

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The positive allosteric modulator of the GABA(B) receptor, rac-BHFF, suppresses alcohol self-administration

The positive allosteric modulator of the GABA(B) receptor, rac-BHFF, suppresses alcohol self-administration

by Maccioni, Paola, Thomas, Andrew W, Carai, Mauro A M, Gessa, Gian Luigi, Malherbe, Pari, Colombo, Giancarlo
Published in Drug and alcohol dependence (01.06.2010)

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Positive Allosteric Modulation of GABAB Receptors Ameliorates Sensorimotor Gating in Rodent Models

Positive Allosteric Modulation of GABAB Receptors Ameliorates Sensorimotor Gating in Rodent Models

by Frau, Roberto, Bini, Valentina, Pillolla, Giuliano, Malherbe, Pari, Pardu, Alessandra, Thomas, Andrew W., Devoto, Paola, Bortolato, Marco
Published in CNS neuroscience & therapeutics (01.07.2014)

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Journal Article Conference Proceeding

Reduction of alcohol intake by the positive allosteric modulator of the GABA(B) receptor, rac-BHFF, in alcohol-preferring rats

Reduction of alcohol intake by the positive allosteric modulator of the GABA(B) receptor, rac-BHFF, in alcohol-preferring rats

by Loi, Barbara, Maccioni, Paola, Lobina, Carla, Carai, Mauro A M, Gessa, Gian Luigi, Thomas, Andrew W, Malherbe, Pari, Colombo, Giancarlo
Published in Alcohol (Fayetteville, N.Y.) (01.02.2013)

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Journal Article

Reduction of alcohol intake by the positive allosteric modulator of the GABAB receptor, rac -BHFF, in alcohol-preferring rats

Reduction of alcohol intake by the positive allosteric modulator of the GABAB receptor, rac -BHFF, in alcohol-preferring rats

by Loi, Barbara, Maccioni, Paola, Lobina, Carla, Carai, Mauro A.M, Gessa, Gian Luigi, Thomas, Andrew W, Malherbe, Pari, Colombo, Giancarlo
Published in Alcohol (Fayetteville, N.Y.) (01.01.2013)

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Journal Article

The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA α5 inverse agonists for the treatment of cognitive dysfunction

by Knust, Henner, Achermann, Guido, Ballard, Theresa, Buettelmann, Bernd, Gasser, Rodolfo, Fischer, Holger, Hernandez, Maria-Clemencia, Knoflach, Frédéric, Koblet, Andreas, Stadler, Heinz, Thomas, Andrew W., Trube, Gerhard, Waldmeier, Pius
Published in Bioorganic & medicinal chemistry letters (01.10.2009)

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Journal Article

The positive allosteric modulator of the GABAB receptor, rac -BHFF, suppresses alcohol self-administration

The positive allosteric modulator of the GABAB receptor, rac -BHFF, suppresses alcohol self-administration

by Maccioni, Paola, Thomas, Andrew W, Carai, Mauro A.M, Gessa, Gian Luigi, Malherbe, Pari, Colombo, Giancarlo
Published in Drug and alcohol dependence (01.06.2010)

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Journal Article

A concise route to triazolobenzodiazepine derivatives via a one-Pot alkyne-Azide cycloaddition reaction

A concise route to triazolobenzodiazepine derivatives via a one-Pot alkyne-Azide cycloaddition reaction

by Thomas, Andrew W
Published in Bioorganic & medicinal chemistry letters (22.07.2002)

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Journal Article

Exercise-induced immunosuppression: roles of reactive oxygen species and 5'-AMP-activated protein kinase dephosphorylation within immune cells

Exercise-induced immunosuppression: roles of reactive oxygen species and 5'-AMP-activated protein kinase dephosphorylation within immune cells

by MOIR, Hannah, HUGHES, Michael G, POTTER, Stephen, SIMS, Craig, BUTCHER, Lee R, DAVIES, Nia A, VERHEGGEN, Kenneth, JONES, Kenneth P, THOMAS, Andrew W, WEBB, Richard
Published in Journal of applied physiology (1985) (01.05.2010)

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