Selective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells
Thirstrup, Kenneth, Dächsel, Justus C., Oppermann, Felix S., Williamson, Douglas S., Smith, Garrick P., Fog, Karina, Christensen, Kenneth V.
Published in Scientific reports (31.08.2017)
Published in Scientific reports (31.08.2017)
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Journal Article
HIF prolyl hydroxylase inhibition increases cell viability and potentiates dopamine release in dopaminergic cells
Johansen, Jens Leander, Sager, Thomas Nikolaj, Lotharius, Julie, Witten, Louise, Mørk, Arne, Egebjerg, Jan, Thirstrup, Kenneth
Published in Journal of neurochemistry (01.10.2010)
Published in Journal of neurochemistry (01.10.2010)
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Journal Article
Nest building performance following MPTP toxicity in mice
Sager, Thomas Nikolaj, Kirchhoff, Jeppe, Mørk, Arne, Van Beek, Johan, Thirstrup, Kenneth, Didriksen, Michael, Lauridsen, Jes Brix
Published in Behavioural brain research (02.04.2010)
Published in Behavioural brain research (02.04.2010)
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Journal Article
Discovery and SAR of a Series of Agonists at Orphan G Protein-Coupled Receptor 139
Shi, Feng, Shen, Jing Kang, Chen, Danqi, Fog, Karina, Thirstrup, Kenneth, Hentzer, Morten, Karlsson, Jens-Jakob, Menon, Veena, Jones, Kenneth A, Smith, Kelli E, Smith, Garrick
Published in ACS medicinal chemistry letters (14.04.2011)
Published in ACS medicinal chemistry letters (14.04.2011)
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Journal Article
Competitive HIF Prolyl Hydroxylase Inhibitors Show Protection against Oxidative Stress by a Mechanism Partially Dependent on Glycolysis
Bergström, Ann-Louise, Fog, Karina, Sager, Thomas Nikolaj, Bruun, Anne Techau, Thirstrup, Kenneth
Published in ISRN neuroscience (05.12.2013)
Published in ISRN neuroscience (05.12.2013)
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Journal Article
Pancreatic Lipase Structure−Function Relationships by Domain Exchange
Carrière, Frédéric, Thirstrup, Kenneth, Hjorth, Siv, Ferrato, Francine, Nielsen, Per F, Withers-Martinez, Chrislaine, Cambillau, Christian, Boel, Esper, Thim, Lars, Verger, Robert
Published in Biochemistry (Easton) (07.01.1997)
Published in Biochemistry (Easton) (07.01.1997)
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Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease
Silva-Fernandes, Anabela, Duarte-Silva, Sara, Neves-Carvalho, Andreia, Amorim, Marina, Soares-Cunha, Carina, Oliveira, Pedro, Thirstrup, Kenneth, Teixeira-Castro, Andreia, Maciel, Patrícia
Published in Neurotherapeutics (01.04.2014)
Published in Neurotherapeutics (01.04.2014)
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Journal Article
Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function
Kristensen, Line V., Oppermann, Felix S., Rauen, Matthias J., Fog, Karina, Schmidt, Thorsten, Schmidt, Jana, Harmuth, Tina, Hartmann-Petersen, Rasmus, Thirstrup, Kenneth
Published in Neurochemistry international (01.01.2018)
Published in Neurochemistry international (01.01.2018)
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Journal Article
Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)
Williamson, Douglas S, Smith, Garrick P, Acheson-Dossang, Pamela, Bedford, Simon T, Chell, Victoria, Chen, I-Jen, Daechsel, Justus C. A, Daniels, Zoe, David, Laurent, Dokurno, Pawel, Hentzer, Morten, Herzig, Martin C, Hubbard, Roderick E, Moore, Jonathan D, Murray, James B, Newland, Samantha, Ray, Stuart C, Shaw, Terry, Surgenor, Allan E, Terry, Lindsey, Thirstrup, Kenneth, Wang, Yikang, Christensen, Kenneth V
Published in Journal of medicinal chemistry (09.11.2017)
Published in Journal of medicinal chemistry (09.11.2017)
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Journal Article
One-step purification and characterization of human pancreatic lipase expressed in insect cells
Thirstrup, Kenneth, Carrière, Frédéric, Hjorth, Siv, Rasmussen, Poul B., Wöldike, Helle, Nielsen, Per F., Thim, Lars
Published in FEBS letters (19.07.1993)
Published in FEBS letters (19.07.1993)
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Journal Article
Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites
Kristensen, Line V., Oppermann, Felix S., Rauen, Matthias J., Hartmann-Petersen, Rasmus, Thirstrup, Kenneth
Published in Neurochemistry international (01.05.2017)
Published in Neurochemistry international (01.05.2017)
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Journal Article
Endogenous 2-oxoglutarate levels impact potencies of competitive HIF prolyl hydroxylase inhibitors
Thirstrup, Kenneth, Christensen, Søren, Møller, Henriette Aaris, Ritzén, Andreas, Bergström, Ann-Louise, Sager, Thomas Nikolaj, Jensen, Henrik Sindal
Published in Pharmacological research (01.09.2011)
Published in Pharmacological research (01.09.2011)
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Journal Article
Linking HSP90 target occupancy to HSP70 induction and efficacy in mouse brain
Thirstrup, Kenneth, Sotty, Florence, Montezinho, Liliana Christina Pereira, Badolo, Lassina, Thougaard, Annemette, Kristjánsson, Maj, Jensen, Thomas, Watson, Stephen, Nielsen, Søren Møller
Published in Pharmacological research (01.02.2016)
Published in Pharmacological research (01.02.2016)
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Journal Article
The Imprinted Gene Neuronatin Is Regulated by Metabolic Status and Associated With Obesity
Vrang, Niels, Meyre, David, Froguel, Phillippe, Jelsing, Jacob, Tang‐Christensen, Mads, Vatin, Vincent, Mikkelsen, Jens D., Thirstrup, Kenneth, Larsen, Leif K., Cullberg, Karina B., Fahrenkrug, Jan, Jacobson, Per, Sjöström, Lars, Carlsson, Lena M.S., Liu, Yongjun, Liu, Xiaogang, Deng, Hong‐Wen, Larsen, Philip J.
Published in Obesity (Silver Spring, Md.) (01.07.2010)
Published in Obesity (Silver Spring, Md.) (01.07.2010)
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Journal Article
HIF prolyl hydroxylase inhibition augments dopamine release in the rat brain in vivo
Witten, Louise, Sager, Thomas, Thirstrup, Kenneth, Johansen, Jens Leander, Larsen, Dorrit Bjerg, Montezinho, Liliana P., Mørk, Arne
Published in Journal of neuroscience research (15.05.2009)
Published in Journal of neuroscience research (15.05.2009)
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