Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model
Sussan, Thomas E, Gajghate, Sachin, Thimmulappa, Rajesh K, Ma, Jinfang, Kim, Jung-Hyun, Sudini, Kuladeep, Consolini, Nicola, Cormier, Stephania A, Lomnicki, Slawo, Hasan, Farhana, Pekosz, Andrew, Biswal, Shyam
Published in PloS one (04.02.2015)
Published in PloS one (04.02.2015)
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Journal Article
Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19
Thimmulappa, Rajesh K., Mudnakudu-Nagaraju, Kiran Kumar, Shivamallu, Chandan, Subramaniam, K.J.Thirumalai, Radhakrishnan, Arun, Bhojraj, Suresh, Kuppusamy, Gowthamarajan
Published in Heliyon (01.02.2021)
Published in Heliyon (01.02.2021)
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Journal Article
Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching
Wei, Yanhong, Gong, Junsong, Thimmulappa, Rajesh K, Kosmider, Beata, Biswal, Shyam, Duh, Elia J
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (08.10.2013)
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Journal Article
Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A
Wei, Yanhong, Gong, Junsong, Xu, Zhenhua, Thimmulappa, Rajesh K., Mitchell, Katherine L., Welsbie, Derek S., Biswal, Shyam, Duh, Elia J.
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
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Journal Article
NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation
Kim, Jung-Hyun, Thimmulappa, Rajesh K, Kumar, Vineet, Cui, Wanchang, Kumar, Sarvesh, Kombairaju, Ponvijay, Zhang, Hao, Margolick, Joseph, Matsui, William, Macvittie, Thomas, Malhotra, Sanjay V, Biswal, Shyam
Published in The Journal of clinical investigation (01.02.2014)
Published in The Journal of clinical investigation (01.02.2014)
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Journal Article
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer
Singh, Anju, Misra, Vikas, Thimmulappa, Rajesh K, Lee, Hannah, Ames, Stephen, Hoque, Mohammad O, Herman, James G, Baylin, Stephen B, Sidransky, David, Gabrielson, Edward, Brock, Malcolm V, Biswal, Shyam
Published in PLoS medicine (01.10.2006)
Published in PLoS medicine (01.10.2006)
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Journal Article
RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy
SINGH, Anju, BOLDIN-ADAMSKY, Swetlana, GABRIELSON, Edward, FEINSTEIN, Elena, BISWAL, Shyam, THIMMULAPPA, Rajesh K, RATH, Srikanta K, ASHUSH, Hagit, COULTER, Jonathan, BLACKFORD, Amanda, GOODMAN, Steven N, BUNZ, Fred, WATSON, Walter H
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Journal Article
Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1
Page, Audrey, Volchkova, Valentina A, Reid, Saint Patrick, Mateo, Mathieu, Bagnaud-Baule, Audrey, Nemirov, Kirill, Shurtleff, Amy C, Lawrence, Philip, Reynard, Oliver, Ottmann, Michele, Lotteau, Vincent, Biswal, Shyam S, Thimmulappa, Rajesh K, Bavari, Sina, Volchkov, Viktor E
Published in Cell reports (Cambridge) (27.03.2014)
Published in Cell reports (Cambridge) (27.03.2014)
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Journal Article
Lipid peroxidation index of particulate matter: Novel metric for quantifying intrinsic oxidative potential and predicting toxic responses
Dey, Sumit K., Sugur, Kavya, Venkatareddy, Venkataramana G., Rajeev, Pradhi, Gupta, Tarun, Thimmulappa, Rajesh K.
Published in Redox biology (01.12.2021)
Published in Redox biology (01.12.2021)
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Journal Article
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
Chukwueke, Ugonma, Bowman, Joel, Cosgrove, Gregory, Petrache, Irina, Shapiro, Steven D, Thimmulappa, Rajesh K, Mao, Tianzhi, Zhen, Lijie, Richter, Amy, Tuder, Rubin M, Mett, Igor, Sussan, Thomas, Zhang, Li, Brown, Emile, Bhunia, Anil K, Notkin, Natalie, Yoshida, Toshinori, Mouded, Majd, Gelfand, Anna, Perez, Mario, Ashush, Hagit, Gandjeva, Aneta, Biswal, Shyam, Feinstein, Elena, Rangasamy, Tirumalai
Published in Nature medicine (01.07.2010)
Published in Nature medicine (01.07.2010)
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Journal Article
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
Rangasamy, Tirumalai, Cho, Chung Y, Thimmulappa, Rajesh K, Zhen, Lijie, Srisuma, Sorachai S, Kensler, Thomas W, Yamamoto, Masayuki, Petrache, Irina, Tuder, Rubin M, Biswal, Shyam
Published in The Journal of clinical investigation (01.11.2004)
Published in The Journal of clinical investigation (01.11.2004)
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Journal Article
Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia‐reperfusion
Xu, Zhenhua, Cho, Hongkwan, Hartsock, Matthew J., Mitchell, Katherine L., Gong, Junsong, Wu, Lijuan, Wei, Yanhong, Wang, Shuang, Thimmulappa, Rajesh K., Sporn, Michael B., Biswal, Shyam, Welsbie, Derek S., Duh, Elia J.
Published in Journal of neurochemistry (01.04.2015)
Published in Journal of neurochemistry (01.04.2015)
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Journal Article
Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide
Thimmulappa, Rajesh K., Scollick, Catherine, Traore, Kassim, Yates, Melinda, Trush, Michael A., Liby, Karen T., Sporn, Michael B., Yamamoto, Masayuki, Kensler, Thomas W., Biswal, Shyam
Published in Biochemical and biophysical research communications (29.12.2006)
Published in Biochemical and biophysical research communications (29.12.2006)
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Journal Article
Role of Nrf2 in protection against intracerebral hemorrhage injury in mice
Wang, Jian, Fields, Jocelyn, Zhao, Chunying, Langer, John, Thimmulappa, Rajesh K., Kensler, Thomas W., Yamamoto, Masayuki, Biswal, Shyam, Doré, Sylvain
Published in Free radical biology & medicine (01.08.2007)
Published in Free radical biology & medicine (01.08.2007)
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Journal Article
Reciprocal enhancement of SARS-CoV-2 and influenza virus replication in human pluripotent stem cell-derived lung organoids
Kim, Min Jung, Kim, Sumi, Kim, Heeyeon, Gil, Dayeon, Han, Hyeong-Jun, Thimmulappa, Rajesh K., Choi, Jang-Hoon, Kim, Jung-Hyun
Published in Emerging microbes & infections (31.12.2023)
Published in Emerging microbes & infections (31.12.2023)
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Journal Article
Glutathione Peroxidase 2, the Major Cigarette Smoke-Inducible Isoform of GPX in Lungs, Is Regulated by Nrf2
Singh, Anju, Rangasamy, Tirumalai, Thimmulappa, Rajesh K, Lee, Hannah, Osburn, William O, Brigelius-Flohe, Regina, Kensler, Thomas W, Yamamoto, Masayuki, Biswal, Shyam
Published in American journal of respiratory cell and molecular biology (01.12.2006)
Published in American journal of respiratory cell and molecular biology (01.12.2006)
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Journal Article
Targeted Inhibition of Anti-Inflammatory Regulator Nrf2 Results in Breast Cancer Retardation In Vitro and In Vivo
Bovilla, Venugopal R, Kuruburu, Mahadevaswamy G, Bettada, Vidya G, Krishnamurthy, Jayashree, Sukocheva, Olga A, Thimmulappa, Rajesh K, Shivananju, Nanjunda Swamy, Balakrishna, Janardhan P, Madhunapantula, SubbaRao V
Published in Biomedicines (30.08.2021)
Published in Biomedicines (30.08.2021)
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Journal Article
Single-Cell RNA Sequencing of Human Pluripotent Stem Cell-Derived Macrophages for Quality Control of The Cell Therapy Product
Jo, Hye-Yeong, Seo, Hyang-Hee, Gil, Dayeon, Park, YoungChan, Han, Hyeong-Jun, Han, Hyo-Won, Thimmulappa, Rajesh K, Kim, Sang Cheol, Kim, Jung-Hyun
Published in Frontiers in genetics (31.01.2022)
Published in Frontiers in genetics (31.01.2022)
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Journal Article
Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages
Han, Hyo-Won, Seo, Hyang-Hee, Jo, Hye-Yeong, Han, Hyeong-jun, Falcão, Virgínia C.A., Delorme, Vincent, Heo, Jinyeong, Shum, David, Choi, Jang-Hoon, Lee, Jin-Moo, Lee, Seung Hun, Heo, Hye-Ryeon, Hong, Seok-Ho, Park, Mi-Hyun, Thimmulappa, Rajesh K., Kim, Jung-Hyun
Published in Stem cell reports (10.12.2019)
Published in Stem cell reports (10.12.2019)
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Journal Article