Coronavirus biology and replication: implications for SARS-CoV-2
V’kovski, Philip, Kratzel, Annika, Steiner, Silvio, Stalder, Hanspeter, Thiel, Volker
Published in Nature reviews. Microbiology (01.03.2021)
Published in Nature reviews. Microbiology (01.03.2021)
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SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation
Schubert, Katharina, Karousis, Evangelos D., Jomaa, Ahmad, Scaiola, Alain, Echeverria, Blanca, Gurzeler, Lukas-Adrian, Leibundgut, Marc, Thiel, Volker, Mühlemann, Oliver, Ban, Nenad
Published in Nature structural & molecular biology (01.10.2020)
Published in Nature structural & molecular biology (01.10.2020)
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Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle
Cong, Yingying, Ulasli, Mustafa, Schepers, Hein, Mauthe, Mario, V'kovski, Philip, Kriegenburg, Franziska, Thiel, Volker, de Haan, Cornelis A M, Reggiori, Fulvio
Published in Journal of virology (31.01.2020)
Published in Journal of virology (31.01.2020)
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Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols
Kratzel, Annika, Todt, Daniel, V'kovski, Philip, Steiner, Silvio, Gultom, Mitra, Thao, Tran Thi Nhu, Ebert, Nadine, Holwerda, Melle, Steinmann, Jörg, Niemeyer, Daniela, Dijkman, Ronald, Kampf, Günter, Drosten, Christian, Steinmann, Eike, Thiel, Volker, Pfaender, Stephanie
Published in Emerging infectious diseases (01.07.2020)
Published in Emerging infectious diseases (01.07.2020)
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Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome
Bhatt, Pramod R., Scaiola, Alain, Loughran, Gary, Leibundgut, Marc, Kratzel, Annika, Meurs, Romane, Dreos, René, O’Connor, Kate M., McMillan, Angus, Bode, Jeffrey W., Thiel, Volker, Gatfield, David, Atkins, John F., Ban, Nenad
Published in Science (18.06.2021)
Published in Science (18.06.2021)
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Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling
V'kovski, Philip, Gerber, Markus, Kelly, Jenna, Pfaender, Stephanie, Ebert, Nadine, Braga Lagache, Sophie, Simillion, Cedric, Portmann, Jasmine, Stalder, Hanspeter, Gaschen, Véronique, Bruggmann, Rémy, Stoffel, Michael H, Heller, Manfred, Dijkman, Ronald, Thiel, Volker
Published in eLife (11.01.2019)
Published in eLife (11.01.2019)
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Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform
Thi Nhu Thao, Tran, Labroussaa, Fabien, Ebert, Nadine, V’kovski, Philip, Stalder, Hanspeter, Portmann, Jasmine, Kelly, Jenna, Steiner, Silvio, Holwerda, Melle, Kratzel, Annika, Gultom, Mitra, Schmied, Kimberly, Laloli, Laura, Hüsser, Linda, Wider, Manon, Pfaender, Stephanie, Hirt, Dagny, Cippà, Valentina, Crespo-Pomar, Silvia, Schröder, Simon, Muth, Doreen, Niemeyer, Daniela, Corman, Victor M., Müller, Marcel A., Drosten, Christian, Dijkman, Ronald, Jores, Joerg, Thiel, Volker
Published in Nature (London) (25.06.2020)
Published in Nature (London) (25.06.2020)
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Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
Tabata, Keisuke, Prasad, Vibhu, Paul, David, Lee, Ji-Young, Pham, Minh-Tu, Twu, Woan-Ing, Neufeldt, Christopher J., Cortese, Mirko, Cerikan, Berati, Stahl, Yannick, Joecks, Sebastian, Tran, Cong Si, Lüchtenborg, Christian, V’kovski, Philip, Hörmann, Katrin, Müller, André C., Zitzmann, Carolin, Haselmann, Uta, Beneke, Jürgen, Kaderali, Lars, Erfle, Holger, Thiel, Volker, Lohmann, Volker, Superti-Furga, Giulio, Brügger, Britta, Bartenschlager, Ralf
Published in Nature communications (14.12.2021)
Published in Nature communications (14.12.2021)
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APOBEC3-mediated restriction of RNA virus replication
Milewska, Aleksandra, Kindler, Eveline, Vkovski, Philip, Zeglen, Slawomir, Ochman, Marek, Thiel, Volker, Rajfur, Zenon, Pyrc, Krzysztof
Published in Scientific reports (13.04.2018)
Published in Scientific reports (13.04.2018)
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LY6E impairs coronavirus fusion and confers immune control of viral disease
Pfaender, Stephanie, Mar, Katrina B., Michailidis, Eleftherios, Kratzel, Annika, Boys, Ian N., V’kovski, Philip, Fan, Wenchun, Kelly, Jenna N., Hirt, Dagny, Ebert, Nadine, Stalder, Hanspeter, Kleine-Weber, Hannah, Hoffmann, Markus, Hoffmann, Hans-Heinrich, Saeed, Mohsan, Dijkman, Ronald, Steinmann, Eike, Wight-Carter, Mary, McDougal, Matthew B., Hanners, Natasha W., Pöhlmann, Stefan, Gallagher, Tom, Todt, Daniel, Zimmer, Gert, Rice, Charles M., Schoggins, John W., Thiel, Volker
Published in Nature microbiology (01.11.2020)
Published in Nature microbiology (01.11.2020)
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TMPRSS2 Activates the Human Coronavirus 229E for Cathepsin-Independent Host Cell Entry and Is Expressed in Viral Target Cells in the Respiratory Epithelium
Bertram, Stephanie, Dijkman, Ronald, Habjan, Matthias, Heurich, Adeline, Gierer, Stefanie, Glowacka, Ilona, Welsch, Kathrin, Winkler, Michael, Schneider, Heike, Hofmann-Winkler, Heike, Thiel, Volker, Pöhlmann, Stefan
Published in Journal of Virology (01.06.2013)
Published in Journal of Virology (01.06.2013)
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Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission
Muth, Doreen, Corman, Victor Max, Roth, Hanna, Binger, Tabea, Dijkman, Ronald, Gottula, Lina Theresa, Gloza-Rausch, Florian, Balboni, Andrea, Battilani, Mara, Rihtarič, Danijela, Toplak, Ivan, Ameneiros, Ramón Seage, Pfeifer, Alexander, Thiel, Volker, Drexler, Jan Felix, Müller, Marcel Alexander, Drosten, Christian
Published in Scientific reports (11.10.2018)
Published in Scientific reports (11.10.2018)
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Ribose 2′- O -methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Thiel, Volker, Züst, Roland, Cervantes-Barragan, Luisa, Habjan, Matthias, Maier, Reinhard, Neuman, Benjamin W, Ziebuhr, John, Szretter, Kristy J, Baker, Susan C, Barchet, Winfried, Diamond, Michael S, Siddell, Stuart G, Ludewig, Burkhard
Published in Nature immunology (01.02.2011)
Published in Nature immunology (01.02.2011)
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Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
Raj, V. Stalin, Mou, Huihui, Smits, Saskia L., Dekkers, Dick H. W., Müller, Marcel A., Dijkman, Ronald, Muth, Doreen, Demmers, Jeroen A. A., Zaki, Ali, Fouchier, Ron A. M., Thiel, Volker, Drosten, Christian, Rottier, Peter J. M., Osterhaus, Albert D. M. E., Bosch, Berend Jan, Haagmans, Bart L.
Published in Nature (London) (14.03.2013)
Published in Nature (London) (14.03.2013)
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Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium
V'kovski, Philip, Gultom, Mitra, Kelly, Jenna N, Steiner, Silvio, Russeil, Julie, Mangeat, Bastien, Cora, Elisa, Pezoldt, Joern, Holwerda, Melle, Kratzel, Annika, Laloli, Laura, Wider, Manon, Portmann, Jasmine, Tran, Thao, Ebert, Nadine, Stalder, Hanspeter, Hartmann, Rune, Gardeux, Vincent, Alpern, Daniel, Deplancke, Bart, Thiel, Volker, Dijkman, Ronald
Published in PLoS biology (29.03.2021)
Published in PLoS biology (29.03.2021)
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Plasmacytoid dendritic cells control T-cell response to chronic viral infection
Cervantes-Barragan, Luisa, Lewis, Kanako L, Firner, Sonja, Thiel, Volker, Hugues, Stephanie, Reith, Walter, Ludewig, Burkhard, Reizis, Boris
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2012)
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