Targeting the α-folate receptor with cyclopenta[ g]quinazoline-based inhibitors of thymidylate synthase
Henderson, Elisa A., Bavetsias, Vassilios, Theti, Davinder S., Wilson, Stuart C., Clauss, Rainer, Jackman, Ann L.
Published in Bioorganic & medicinal chemistry (15.07.2006)
Published in Bioorganic & medicinal chemistry (15.07.2006)
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Journal Article
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to α-folate receptor-overexpressing tumors
GIBBS, David D, THETI, Davinder S, JACKMAN, Ann L, WOOD, Nadya, GREEN, Matthew, RAYNAUD, Florence, VALENTI, Melanie, FORSTER, Martin D, MITCHELL, Fraser, BAVETSIAS, Vassilios, HENDERSON, Elisa
Published in Cancer research (Chicago, Ill.) (15.12.2005)
Published in Cancer research (Chicago, Ill.) (15.12.2005)
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Journal Article
Antifolates targeted specifically to the folate receptor
Jackman, Ann L, Theti, Davinder S, Gibbs, David D
Published in Advanced drug delivery reviews (29.04.2004)
Published in Advanced drug delivery reviews (29.04.2004)
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Journal Article
Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the α-isoform of the folate receptor
THETI, Davinder S, BAVETSIAS, Vassilios, SKELTON, Lorraine A, TITLEY, Jenny, GIBBS, David, JANSEN, Gerrit, JACKMAN, Ann L
Published in Cancer research (Chicago, Ill.) (01.07.2003)
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Published in Cancer research (Chicago, Ill.) (01.07.2003)
Journal Article
A rationale for the clinical development of the thymidylate synthase inhibitor ZD9331 in ovarian and other solid tumours
Jackman, Ann L, Melin, Camille J, Kimbell, Rosemary, Brunton, Lisa, Aherne, G.Wynne, Theti, Davinder S, Walton, Mike
Published in BBA - Molecular Basis of Disease (18.07.2002)
Published in BBA - Molecular Basis of Disease (18.07.2002)
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Book Review
Journal Article
Abstract 2544: Preclinical pharmacodynamics (PD) of ONX 0801, a folate receptor-α (FRα) and tumor-targeted thymidylate synthase (TS) inhibitor
Ng, Chau HM, Valenti, Melanie, Ruddle, Ruth, Raynaud, Florence, Theti, Davinder S., Mitchell, Fraser, Jackman, Ann L.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article