Quenching protein dynamics interferes with HIV capsid maturation
Wang, Mingzhang, Quinn, Caitlin M., Perilla, Juan R., Zhang, Huilan, Shirra Jr, Randall, Hou, Guangjin, Byeon, In-Ja, Suiter, Christopher L., Ablan, Sherimay, Urano, Emiko, Nitz, Theodore J., Aiken, Christopher, Freed, Eric O., Zhang, Peijun, Schulten, Klaus, Gronenborn, Angela M., Polenova, Tatyana
Published in Nature communications (24.11.2017)
Published in Nature communications (24.11.2017)
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Journal Article
Resistance to Second-Generation HIV-1 Maturation Inhibitors
Urano, Emiko, Timilsina, Uddhav, Kaplan, Justin A, Ablan, Sherimay, Ghimire, Dibya, Pham, Phuong, Kuruppu, Nishani, Mandt, Rebecca, Durell, Stewart R, Nitz, Theodore J, Martin, David E, Wild, Carl T, Gaur, Ritu, Freed, Eric O
Published in Journal of virology (15.03.2019)
Published in Journal of virology (15.03.2019)
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Journal Article
The prototype HIV-1 maturation inhibitor, bevirimat, binds to the CA-SP1 cleavage site in immature Gag particles
Nguyen, Albert T, Feasley, Christa L, Jackson, Ken W, Nitz, Theodore J, Salzwedel, Karl, Air, Gillian M, Sakalian, Michael
Published in Retrovirology (07.12.2011)
Published in Retrovirology (07.12.2011)
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Journal Article
Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors
Urano, Emiko, Ablan, Sherimay D, Mandt, Rebecca, Pauly, Gary T, Sigano, Dina M, Schneider, Joel P, Martin, David E, Nitz, Theodore J, Wild, Carl T, Freed, Eric O
Published in Antimicrobial agents and chemotherapy (01.01.2016)
Published in Antimicrobial agents and chemotherapy (01.01.2016)
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Journal Article
Identification of potent maturation inhibitors against HIV-1 clade C
Timilsina, Uddhav, Ghimire, Dibya, Timalsina, Bivek, Nitz, Theodore J., Wild, Carl T., Freed, Eric O., Gaur, Ritu
Published in Scientific reports (06.06.2016)
Published in Scientific reports (06.06.2016)
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Journal Article
Anti-AIDS Agents. 78. Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (HIV) Agents
Qian, Keduo, Yu, Donglei, Chen, Chin-Ho, Huang, Li, Morris-Natschke, Susan L, Nitz, Theodore J, Salzwedel, Karl, Reddick, Mary, Allaway, Graham P, Lee, Kuo-Hsiung
Published in Journal of medicinal chemistry (28.05.2009)
Published in Journal of medicinal chemistry (28.05.2009)
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Journal Article
Anti-AIDS agents 73: Structure–activity relationship study and asymmetric synthesis of 3- O-monomethylsuccinyl-betulinic acid derivatives
Qian, Keduo, Nakagawa-Goto, Kyoko, Yu, Donglei, Morris-Natschke, Susan L., Nitz, Theodore J., Kilgore, Nicole, Allaway, Graham P., Lee, Kuo-Hsiung
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
Published in Bioorganic & medicinal chemistry letters (01.12.2007)
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Journal Article
Antipicornavirus activity of tetrazole analogs related to disoxaril
Diana, Guy D, Cutcliffe, David, Volkots, Deborah L, Mallamo, John P, Bailey, Thomas R, Vescio, Niranjan, Oglesby, Richard C, Nitz, Theodore J, Wetzel, Joseph
Published in Journal of medicinal chemistry (01.10.1993)
Published in Journal of medicinal chemistry (01.10.1993)
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Journal Article
Antiviral efficacy of VP14637 against respiratory syncytial virus in vitro and in cotton rats following delivery by small droplet aerosol
Wyde, Philip R., Laquerre, Sylvie, Chetty, Srikrishna N., Gilbert, Brian E., Nitz, Theodore J., Pevear, Daniel C.
Published in Antiviral research (01.10.2005)
Published in Antiviral research (01.10.2005)
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Journal Article
Oxadiazoles as Ester Bioisosteric Replacements in Compounds Related to Disoxaril. Antirhinovirus Activity
Diana, Guy D, Volkots, Deborah L, Nitz, Theodore J, Bailey, Thomas R, Long, Melody A, Vescio, Niranjan, Aldous, Suzanne, Pevear, Daniel C, Dutko, Frank J
Published in Journal of medicinal chemistry (01.07.1994)
Published in Journal of medicinal chemistry (01.07.1994)
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Journal Article
Parallel synthesis of 1,2,4-oxadiazoles using CDI activation
Deegan, Tracy L, Nitz, Theodore J, Cebzanov, Diane, Pufko, Denise E, Porco, John A
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
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Journal Article
Picornavirus Inhibitors: Trifluoromethyl Substitution Provides a Global Protective Effect against Hepatic Metabolism
Diana, Guy D, Rudewicz, Patrick, Pevear, Daniel C, Nitz, Theodore J, Aldous, Suzanne C, Aldous, David J, Robinson, David T, Draper, Tandy, Dutko, Frank J
Published in Journal of medicinal chemistry (01.04.1995)
Published in Journal of medicinal chemistry (01.04.1995)
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Journal Article
Ingenane synthetic studies. An expedient approach to highly oxygenated ABC subunits of ingenol via reductive dialkylative annulation and .alpha.,.beta.-epoxy ketone photoisomerization
Paquette, Leo A, Nitz, Theodore J, Ross, Robert J, Springer, James P
Published in Journal of the American Chemical Society (01.03.1984)
Published in Journal of the American Chemical Society (01.03.1984)
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Journal Article
An excursion into the synthesis of potential angiotensin converting enzyme inhibitors
Nitz, Theodore J, Lindsey, John, Stammer, Charles H
Published in Journal of organic chemistry (01.10.1982)
Published in Journal of organic chemistry (01.10.1982)
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Journal Article
N-[(Carbobenzyl)oxy]-.DELTA.E-phenylalanine ethyl ester
Nitz, Theodore J, Holt, Elizabeth M, Rubin, Byron, Stammer, Charles H
Published in Journal of organic chemistry (01.06.1981)
Published in Journal of organic chemistry (01.06.1981)
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Journal Article