Search Results - "THACKRAY HELEN M" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Use of GMI‐1271, an E‐selectin antagonist, in healthy subjects and in 2 patients with calf vein thrombosis

Use of GMI‐1271, an E‐selectin antagonist, in healthy subjects and in 2 patients with calf vein thrombosis

by Devata, Sumana, Angelini, Dana E., Blackburn, Susan, Hawley, Angela, Myers, Daniel D., Schaefer, Jordan K., Hemmer, Martina, Magnani, John L., Thackray, Helen M., Wakefield, Thomas W., Sood, Suman L.
Published in Research and practice in thrombosis and haemostasis (01.02.2020)

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Journal Article

Phase 1/2 Double-Blind, Placebo-Controlled, Dose Escalation, Safety, and Pharmacokinetic Study of Pagibaximab (BSYX-A110), an Antistaphylococcal Monoclonal Antibody for the Prevention of Staphylococcal Bloodstream Infections, in Very-Low-Birth-Weight Neonates

Phase 1/2 Double-Blind, Placebo-Controlled, Dose Escalation, Safety, and Pharmacokinetic Study of Pagibaximab (BSYX-A110), an Antistaphylococcal Monoclonal Antibody for the Prevention of Staphylococcal Bloodstream Infections, in Very-Low-Birth-Weight Neonates

by Weisman, Leonard E, Thackray, Helen M, Garcia-Prats, Joseph A, Nesin, Mirjana, Schneider, Joseph H, Fretz, Jennifer, Kokai-Kun, John F, Mond, James J, Kramer, William G, Fischer, Gerald W
Published in Antimicrobial Agents and Chemotherapy (01.07.2009)

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Journal Article

$Phase 1/2 study of uproleselan added to chemotherapy in patients with relapsed or refractory acute myeloid leukemia$

Phase 1/2 study of uproleselan added to chemotherapy in patients with relapsed or refractory acute myeloid leukemia

by DeAngelo, Daniel J., Jonas, Brian A., Liesveld, Jane L., Bixby, Dale L., Advani, Anjali S., Marlton, Paula, Magnani, John L., Thackray, Helen M., Feldman, Eric J., O'Dwyer, Michael E., Becker, Pamela S.
Published in Blood (24.02.2022)

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Journal Article

A randomized study of a monoclonal antibody (pagibaximab) to prevent staphylococcal sepsis

A randomized study of a monoclonal antibody (pagibaximab) to prevent staphylococcal sepsis

by Weisman, Leonard E, Thackray, Helen M, Steinhorn, Robin H, Walsh, William F, Lassiter, Herbert A, Dhanireddy, Ramasubbareddy, Brozanski, Beverly S, Palmer, Kristine G H, Trautman, Michael S, Escobedo, Marilyn, Meissner, H Cody, Sasidharan, Pontthenkandath, Fretz, Jennifer, Kokai-Kun, John F, Kramer, William G, Fischer, Gerald W, Mond, James J
Published in Pediatrics (Evanston) (01.08.2011)

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Journal Article

Safety and pharmacokinetics of a chimerized anti-lipoteichoic acid monoclonal antibody in healthy adults

Safety and pharmacokinetics of a chimerized anti-lipoteichoic acid monoclonal antibody in healthy adults

by Weisman, Leonard E., Fischer, Gerald W., Thackray, Helen M., Johnson, Karen E., Schuman, Richard F., Mandy, George T., Stratton, Beth E., Adams, Karen M., Kramer, William G., Mond, James J.
Published in International immunopharmacology (01.05.2009)

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Journal Article

급성 골수성 백혈병 및 관련 병태의 치료 방법

급성 골수성 백혈병 및 관련 병태의 치료 방법

by WOLFGANG CURT D, THACKRAY HELEN M, FLANNER HENRY H
Year of Publication 11.11.2020

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Patent

Administration of the Dual E-Selectin/CXCR4 Antagonist, GMI-1359, Results in a Unique Profile of Tumor Mobilization from the Bone Marrow and Facilitation of Chemotherapy in a Murine Model of FLT3 ITD AML

by Fogler, William E., Flanner, Henry, Wolfgang, Curt, Smith, Jeffrey Allen, Thackray, Helen M., Magnani, John L
Published in Blood (02.12.2016)

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Journal Article

E-Selectin Ligand Expression By Leukemic Blasts Is Associated with Prognosis in Patients with AML

E-Selectin Ligand Expression By Leukemic Blasts Is Associated with Prognosis in Patients with AML

by Chien, Sylvia S, Dai, Jin, Magnani, John L, Sekizaki, Taylor S, Fogler, William E, Thackray, Helen M, Gardner, Kelda, Estey, Elihu H., Becker, Pamela S
Published in Blood (29.11.2018)

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Journal Article

$High E-Selectin Ligand Expression Contributes to Chemotherapy-Resistance in Poor Risk Relapsed and Refractory (R/R) Acute Myeloid Leukemia (AML) Patients and Can be Overcome with the Addition of Uproleselan$

High E-Selectin Ligand Expression Contributes to Chemotherapy-Resistance in Poor Risk Relapsed and Refractory (R/R) Acute Myeloid Leukemia (AML) Patients and Can be Overcome with the Addition of Uproleselan

by DeAngelo, Daniel J., Jonas, Brian A, Liesveld, Jane L., Bixby, Dale L., Advani, Anjali S., Marlton, Paula, O'Dwyer, Michael E, Fogler, William E., Magnani, John L., Chen, Mary M, Feldman, Eric J., Thackray, Helen M, Becker, Pamela S.
Published in Blood (13.11.2019)

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Journal Article

Early Initiation of Treatment with Rivipansel for Acute Vaso-Occlusive Crisis in Sickle Cell Disease (SCD) Achieves Earlier Discontinuation of IV Opioids and Shorter Hospital Stay: Reset Clinical Trial Analysis

Early Initiation of Treatment with Rivipansel for Acute Vaso-Occlusive Crisis in Sickle Cell Disease (SCD) Achieves Earlier Discontinuation of IV Opioids and Shorter Hospital Stay: Reset Clinical Trial Analysis

by Dampier, Carlton D., Telen, Marilyn J., Wun, Ted, Smith, Wally R, Brown, R. Clark, Desai, Payal, El Rassi, Fuad A, Kanter, Julie, Fuh, Beng R., Pastore, Yves D., Rothman, Jennifer A., Taylor, James G., Readett, David, Lozier, Jay N, Magnani, John L., Thackray, Helen M, Hassell, Kathryn L.
Published in Blood (05.11.2020)

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Journal Article

$A phase III trial to evaluate the efficacy of uproleselan (GMI-1271) with chemotherapy in patients with relapsed/refractory acute myeloid leukemia$

A phase III trial to evaluate the efficacy of uproleselan (GMI-1271) with chemotherapy in patients with relapsed/refractory acute myeloid leukemia

by DeAngelo, Daniel J., Erba, Harry Paul, Jonas, Brian Andrew, O'Dwyer, Michael, Marlton, Paula, Huls, Gerwin A, Liesveld, Jane, Cooper, Brenda W., Bhatnagar, Bhavana, Armstrong, Michael, Fogler, William, Chen, Mary, Magnani, John, Thackray, Helen M., Advani, Anjali S., Becker, Pamela Sue
Published in Journal of clinical oncology (20.05.2019)

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Journal Article

GMI-1271 Improves Efficacy and Safety of Chemotherapy in R/R and Newly Diagnosed Older Patients with AML: Results of a Phase 1/2 Study

GMI-1271 Improves Efficacy and Safety of Chemotherapy in R/R and Newly Diagnosed Older Patients with AML: Results of a Phase 1/2 Study

by DeAngelo, Daniel J., Jonas, Brian A, Liesveld, Jane L., Bixby, Dale L., Advani, Anjali S., Marlton, Paula, O'Dwyer, Michael, Magnani, John L, Thackray, Helen M., Becker, Pamela S.
Published in Blood (08.12.2017)

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Journal Article

$Uproleselan (GMI-1271), an E-Selectin Antagonist, Improves the Efficacy and Safety of Chemotherapy in Relapsed/Refractory (R/R) and Newly Diagnosed Older Patients with Acute Myeloid Leukemia: Final, Correlative, and Subgroup Analyses$

Uproleselan (GMI-1271), an E-Selectin Antagonist, Improves the Efficacy and Safety of Chemotherapy in Relapsed/Refractory (R/R) and Newly Diagnosed Older Patients with Acute Myeloid Leukemia: Final, Correlative, and Subgroup Analyses

by DeAngelo, Daniel J., Jonas, Brian A., Liesveld, Jane L., Bixby, Dale L., Advani, Anjali S., Marlton, Paula, O'Dwyer, Michael E, Fogler, William E, Wolfgang, Curt D, Magnani, John L, Thackray, Helen M, Becker, Pamela S.
Published in Blood (29.11.2018)

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Journal Article

GMI-1271, a novel E-selectin antagonist, combined with induction chemotherapy in elderly patients with untreated AML

GMI-1271, a novel E-selectin antagonist, combined with induction chemotherapy in elderly patients with untreated AML

by DeAngelo, Daniel J., Jonas, Brian Andrew, Becker, Pamela S., O'Dwyer, Michael, Advani, Anjali S., Marlton, Paula, Magnani, John, Thackray, Helen M., Liesveld, Jane
Published in Journal of clinical oncology (20.05.2017)

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Journal Article

$GMI-1271, a novel E-selectin antagonist, in combination with chemotherapy in relapsed/refractory AML$

GMI-1271, a novel E-selectin antagonist, in combination with chemotherapy in relapsed/refractory AML

by DeAngelo, Daniel J., Jonas, Brian Andrew, Liesveld, Jane, O'Dwyer, Michael, Bixby, Dale, Advani, Anjali S., Marlton, Paula, Magnani, John, Thackray, Helen M., Becker, Pamela S.
Published in Journal of clinical oncology (20.05.2017)

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Journal Article

$A Double-Blind, Placebo-Controlled, Phase 3 Registration Trial to Evaluate the Efficacy of Uproleselan (GMI-1271) with Standard Salvage Chemotherapy in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia$

A Double-Blind, Placebo-Controlled, Phase 3 Registration Trial to Evaluate the Efficacy of Uproleselan (GMI-1271) with Standard Salvage Chemotherapy in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia

by DeAngelo, Daniel J., Erba, Harry P., Jonas, Brian A, O'Dwyer, Michael E, Marlton, Paula, Huls, Gerwin, Liesveld, Jane L., Cooper, Brenda, Bhatnagar, Bhavana, Uy, Geoffrey L., Cull, Gavin, Armstrong, Michael B., Fogler, William E., Chen, Mary M, Magnani, John L., Thackray, Helen M, Feldman, Eric J., Advani, Anjali S., Becker, Pamela S.
Published in Blood (13.11.2019)

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Journal Article

$A Phase I/II Study of GMI-1271, a Novel E-Selectin Antagonist, in Combination with Induction Chemotherapy in Relapsed/Refractory and Elderly Previously Untreated Acute Myeloid Leukemia; Results to Date$

A Phase I/II Study of GMI-1271, a Novel E-Selectin Antagonist, in Combination with Induction Chemotherapy in Relapsed/Refractory and Elderly Previously Untreated Acute Myeloid Leukemia; Results to Date

by DeAngelo, Daniel J., Liesveld, Jane L., Jonas, Brian A, O'Dwyer, Michael E, Bixby, Dale L., Magnani, John L, Thackray, Helen M., Becker, Pamela S.
Published in Blood (02.12.2016)

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Journal Article

First in Human Phase 1 Single Dose Escalation Studies of the E-Selectin Antagonist GMI-1271 Show a Favorable Safety, Pharmacokinetic, and Biomarker Profile

by Devata, Sumana, Sood, Suman L., Hemmer, Martina V, Flanner, Henry, Kramer, William, Nietubicz, Christine, Hawley, Angela, Angelini, Dana E, Myers, Daniel Durant, Blackburn, Susan, Froehlich, James, Wakefield, Thomas W., Magnani, John L., Thackray, Helen M.
Published in Blood (03.12.2015)

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Journal Article

E-Selectin Antagonist GMI-1271 Shows a Favorable Safety, PK and Bleeding Profile in Phase I Studies of Healthy Volunteers

by Angelini, Dana E., Devata, Sumana, Hawley, Angela E., Blackburn, Susan A., Grewal, Satwinder, Hemmer, Martina V, Flanner, Henry, Kramer, William, Parker, William E, Li, Yu-Ling, Myers, Daniel Durant, Froehlich, James B., Magnani, John L, Thackray, Helen M., Wakefield, Thomas W., Sood, Suman L.
Published in Blood (02.12.2016)

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Journal Article

Pan-Selectin Antagonist Rivipansel (GMI-1070) Reduces Soluble E-Selectin Levels While Improving Clinical Outcomes in SCD Vaso-Occlusive Crisis

Pan-Selectin Antagonist Rivipansel (GMI-1070) Reduces Soluble E-Selectin Levels While Improving Clinical Outcomes in SCD Vaso-Occlusive Crisis

by Wun, Ted, Telen, Marilyn J., Krishnamurti, Lakshmanan, McCavit, Timothy L., DeCastro, Laura M, Flanner, Henry, Kuypers, Frans A., Larkin, Sandra K., Rhee, Seungshin, Magnani, John L., Thackray, Helen M.
Published in Blood (06.12.2014)

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