Synthesis of novel Iron(III) chelators based on triaza macrocycle backbone and 1-hydroxy-2(H)-pyridin-2-one coordinating groups and their evaluation as antimicrobial agents
Workman, David G., Hunter, Michael, Dover, Lynn G., Tétard, David
Published in Journal of inorganic biochemistry (01.07.2016)
Published in Journal of inorganic biochemistry (01.07.2016)
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Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1 H )-one iron chelators in an in vitro cell model of Parkinson's disease
Lewis, Frank W, Bird, Kathleen, Navarro, Jean-Philippe, El Fallah, Rawa, Brandel, Jeremy, Hubscher-Bruder, Véronique, Tsatsanis, Andrew, Duce, James A, Tétard, David, Bourne, Samuel, Maina, Mahmoud, Pienaar, Ilse S
Published in Dalton transactions : an international journal of inorganic chemistry (01.03.2022)
Published in Dalton transactions : an international journal of inorganic chemistry (01.03.2022)
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The influence of linkages between 1-hydroxy-2(1H)-pyridinone coordinating groups and a tris(2-aminoethyl)amine core in a novel series of synthetic hexadentate iron(III) chelators on antimicrobial activity
Workman, David G., Hunter, Michael, Wang, Shuning, Brandel, Jérémy, Hubscher, Véronique, Dover, Lynn G., Tétard, David
Published in Bioorganic chemistry (01.01.2020)
Published in Bioorganic chemistry (01.01.2020)
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Novel 1-hydroxypyridin-2-one metal chelators prevent and rescue ubiquitin proteasomal-related neuronal injury in an in vitro model of Parkinson’s disease
Lewis, Frank W., Fairooz, Safiya, Elson, Joanna L., Hubscher-Bruder, Véronique, Brandel, Jeremy, Soundararajan, Meera, Smith, David, Dexter, David T., Tétard, David, Pienaar, Ilse S.
Published in Archives of toxicology (01.03.2020)
Published in Archives of toxicology (01.03.2020)
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Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators
Workman, David G, Tsatsanis, Andrew, Lewis, Frank W, Boyle, John P, Mousadoust, Maryam, Hettiarachchi, Nishani T, Hunter, Michael, Peers, Chris S, Tétard, David, Duce, James A
Published in Metallomics (01.05.2015)
Published in Metallomics (01.05.2015)
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1-Hydroxy-2(1 H )-pyridinone-Based Chelators with Potential Catechol O -Methyl Transferase Inhibition and Neurorescue Dual Action against Parkinson's Disease
Bergin, Joseph C J, Tan, Kean Kan, Nelson, Anya K, Amarandei, Cristina-Andreea, Hubscher-Bruder, Véronique, Brandel, Jérémy, Voinarovska, Varvara, Dejaegere, Annick, Stote, Roland H, Tétard, David
Published in Molecules (Basel, Switzerland) (28.04.2022)
Published in Molecules (Basel, Switzerland) (28.04.2022)
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Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants
Gutbier, Simon, Kyriakou, Sotiris, Schildknecht, Stefan, Ückert, Anna-Katharina, Brüll, Markus, Lewis, Frank, Dickens, David, Pearson, Liam, Elson, Joanna L., Michel, Sylvia, Hubscher-Bruder, Véronique, Brandel, Jeremy, Tetard, David, Leist, Marcel, Pienaar, Ilse S.
Published in Archives of toxicology (01.09.2020)
Published in Archives of toxicology (01.09.2020)
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Novel Iron Chelator SK4 Drives Cytotoxicity through Inhibiting Mitochondrial Metabolism in Ovarian and Triple Negative Breast Cancer Cell Lines
Abdelaal, Gina, Carter, Andrew, Cheung, William, Panayiotidis, Mihalis, Racey, Seth, Tétard, David, Veuger, Stephany
Published in Biomedicines (01.07.2023)
Published in Biomedicines (01.07.2023)
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Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma
Kyriakou, Sotiris, Mitsiogianni, Melina, Mantso, Theodora, Cheung, William, Todryk, Stephen, Veuger, Stephany, Pappa, Aglaia, Tetard, David, Panayiotidis, Mihalis I.
Published in Investigational new drugs (01.06.2020)
Published in Investigational new drugs (01.06.2020)
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A novel methylated analogue of L-Mimosine exerts its therapeutic potency through ROS production and ceramide-induced apoptosis in malignant melanoma
Kyriakou, Sotiris, Cheung, William, Mantso, Theodora, Mitsiogianni, Melina, Anestopoulos, Ioannis, Veuger, Stephany, Trafalis, Dimitris T., Franco, Rodrigo, Pappa, Aglaia, Tetard, David, Panayiotidis, Mihalis I.
Published in Investigational new drugs (01.08.2021)
Published in Investigational new drugs (01.08.2021)
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Electrochemically Induced Dynamics of a Benzylic Amide [2]Catenane
Ceroni, Paola, Leigh, David A, Mottier, Loïc, Paolucci, Francesco, Roffia, Sergio, Tetard, David, Zerbetto, Francesco
Published in The journal of physical chemistry. B (18.11.1999)
Published in The journal of physical chemistry. B (18.11.1999)
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Alkane hydroxylation reactions catalysed by binuclear manganese and iron complexes
Tetard, David, Verlhac, Jean-Baptiste
Published in Journal of molecular catalysis. A, Chemical (25.11.1996)
Published in Journal of molecular catalysis. A, Chemical (25.11.1996)
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Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1)-one iron chelators in an cell model of Parkinson's disease
Lewis, Frank W, Bird, Kathleen, Navarro, Jean-Philippe, El Fallah, Rawa, Brandel, Jeremy, Hubscher-Bruder, Véronique, Tsatsanis, Andrew, Duce, James A, Tétard, David, Bourne, Samuel, Maina, Mahmoud, Pienaar, Ilse S
Published in Dalton transactions : an international journal of inorganic chemistry (01.03.2022)
Published in Dalton transactions : an international journal of inorganic chemistry (01.03.2022)
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