The signalling conformation of the insulin receptor ectodomain
Weis, Felix, Menting, John G., Margetts, Mai B., Chan, Shu Jin, Xu, Yibin, Tennagels, Norbert, Wohlfart, Paulus, Langer, Thomas, Müller, Christoph W., Dreyer, Matthias K., Lawrence, Michael C.
Published in Nature communications (24.10.2018)
Published in Nature communications (24.10.2018)
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Journal Article
BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells
Elsen, Manuela, Raschke, Silja, Tennagels, Norbert, Schwahn, Uwe, Jelenik, Tomas, Roden, Michael, Romacho, Tania, Eckel, Jürgen
Published in American Journal of Physiology: Cell Physiology (01.03.2014)
Published in American Journal of Physiology: Cell Physiology (01.03.2014)
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Journal Article
Molecular basis for inhibiting human glucose transporters by exofacial inhibitors
Wang, Nan, Zhang, Shuo, Yuan, Yafei, Xu, Hanwen, Defossa, Elisabeth, Matter, Hans, Besenius, Melissa, Derdau, Volker, Dreyer, Matthias, Halland, Nis, He, Kaihui Hu, Petry, Stefan, Podeschwa, Michael, Tennagels, Norbert, Jiang, Xin, Yan, Nieng
Published in Nature communications (12.05.2022)
Published in Nature communications (12.05.2022)
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Journal Article
The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach
Raichur, Suryaprakash, Brunner, Bodo, Bielohuby, Maximilian, Hansen, Gitte, Pfenninger, Anja, Wang, Bing, Bruning, Jens C., Larsen, Philip Just, Tennagels, Norbert
Published in Molecular metabolism (Germany) (01.03.2019)
Published in Molecular metabolism (Germany) (01.03.2019)
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Journal Article
In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites
Sommerfeld, Mark R, Müller, Günter, Tschank, Georg, Seipke, Gerhard, Habermann, Paul, Kurrle, Roland, Tennagels, Norbert
Published in PloS one (04.03.2010)
Published in PloS one (04.03.2010)
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Journal Article
Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila
Grönke, Sebastian, Mildner, Alexander, Fellert, Sonja, Tennagels, Norbert, Petry, Stefan, Müller, Günter, Jäckle, Herbert, Kühnlein, Ronald P.
Published in Cell metabolism (01.05.2005)
Published in Cell metabolism (01.05.2005)
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Journal Article
Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2
Pierre-Eugene, Cécile, Pagesy, Patrick, Nguyen, Tuyet Thu, Neuillé, Marion, Tschank, Georg, Tennagels, Norbert, Hampe, Cornelia, Issad, Tarik
Published in PloS one (26.07.2012)
Published in PloS one (26.07.2012)
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Journal Article
9-PAHSA displays a weak anti-inflammatory potential mediated by specific antagonism of chemokine G protein-coupled receptors
Wohlfart, Paulus, Chehtane, Mounir, Luna, Ernesto, Mehta, Riyaz, Korn, Marcus, Konkar, Anish, Schwahn, Uwe, Petry, Stefan, Tennagels, Norbert, Bielohuby, Maximilian
Published in Frontiers in drug discovery (20.07.2023)
Published in Frontiers in drug discovery (20.07.2023)
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Journal Article
Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice
Ardaiz, Nuria, Gomar, Celia, Vasquez, Marcos, Tenesaca, Shirley, Fernandez-Sendin, Myriam, Di Trani, Claudia Augusta, Belsué, Virginia, Escalada, Javier, Werner, Ulrich, Tennagels, Norbert, Berraondo, Pedro
Published in Frontiers in pharmacology (19.02.2021)
Published in Frontiers in pharmacology (19.02.2021)
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Journal Article
Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human immune model
Luna, Ernesto, Agrawal, Pankaj, Mehta, Riyaz, Boone, Maria E, Vernhes, Charlotte, Denys, Colombe, Small, Robert, Mukherjee, Bhaswati, Tennagels, Norbert, Maerten, Stefan, Drake, 3rd, Donald R
Published in PloS one (06.06.2018)
Published in PloS one (06.06.2018)
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Journal Article
Liver-Specific Knockdown of Class IIa HDACs Has Limited Efficacy on Glucose Metabolism but Entails Severe Organ Side Effects in Mice
Ziegler, Nicole, Raichur, Suryaprakash, Brunner, Bodo, Hemmann, Ulrike, Stolte, Manuela, Schwahn, Uwe, Prochnow, Hans-Peter, Metz-Weidmann, Christiane, Tennagels, Norbert, Margerie, Daniel, Wohlfart, Paulus, Bielohuby, Maximilian
Published in Frontiers in endocrinology (Lausanne) (28.08.2020)
Published in Frontiers in endocrinology (Lausanne) (28.08.2020)
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Journal Article
Dysregulated pyruvate dehydrogenase complex in Zucker diabetic fatty rats
Schummer, Christoph M, Werner, Ulrich, Tennagels, Norbert, Schmoll, Dieter, Haschke, Guido, Juretschke, Hans-Paul, Patel, Mulchand S, Gerl, Martin, Kramer, Werner, Herling, Andreas W
Published in American journal of physiology: endocrinology and metabolism (01.01.2008)
Published in American journal of physiology: endocrinology and metabolism (01.01.2008)
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Journal Article
The metabolic and mitogenic properties of basal insulin analogues
Tennagels, Norbert, Werner, Ulrich
Published in Archives of physiology and biochemistry (01.02.2013)
Published in Archives of physiology and biochemistry (01.02.2013)
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Journal Article
Equipotency of insulin glargine 300 and 100 U/mL with intravenous dosing but differential bioavailability with subcutaneous dosing in dogs
Werner, Ulrich, Tennagels, Norbert, Fanelli, Carmine G., Bolli, Geremia B.
Published in Diabetes, obesity & metabolism (01.01.2021)
Published in Diabetes, obesity & metabolism (01.01.2021)
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Journal Article
Facile folding of insulin variants bearing a prosthetic C-peptide prepared by -ketoacid-hydroxylamine (KAHA) ligation
Boross, Gabor N., Shimura, Satomi, Besenius, Melissa, Tennagels, Norbert, Rossen, Kai, Wagner, Michael, Bode, Jeffrey W.
Published in Chemical science (Cambridge) (28.11.2018)
Published in Chemical science (Cambridge) (28.11.2018)
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Journal Article
Acute and Repeated Treatment with 5-PAHSA or 9-PAHSA Isomers Does Not Improve Glucose Control in Mice
Pflimlin, Elsa, Bielohuby, Maximilian, Korn, Marcus, Breitschopf, Kristin, Löhn, Matthias, Wohlfart, Paulus, Konkar, Anish, Podeschwa, Michael, Bärenz, Felix, Pfenninger, Anja, Schwahn, Uwe, Opatz, Till, Reimann, Marcel, Petry, Stefan, Tennagels, Norbert
Published in Cell metabolism (07.08.2018)
Published in Cell metabolism (07.08.2018)
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Journal Article
Comparison of metabolic and mitogenic response in vitro of the rapid-acting insulin lispro product SAR342434, and US- and EU-approved Humalog
Korn, Marcus, Wohlfart, Paulus, Gossas, Thomas, Kullman-Magnusson, Mari, Niederhaus, Birgit, Dedio, Juergen, Tennagels, Norbert
Published in Regulatory toxicology and pharmacology (01.12.2019)
Published in Regulatory toxicology and pharmacology (01.12.2019)
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Journal Article