Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
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Published in Infection and Immunity (01.01.1995)
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Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease
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Published in The Journal of experimental medicine (01.05.1994)
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THE DESIGN OF VACCINES AGAINST HELICOBACTER PYLORI AND THEIR DEVELOPMENT
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Impaired T-cell regulation of B-cell growth in Helicobacter pylori--related gastric low-grade MALT lymphoma
D'Elios, M M, Amedei, A, Manghetti, M, Costa, F, Baldari, C T, Quazi, A S, Telford, J L, Romagnani, S, Del Prete, G
Published in Gastroenterology (New York, N.Y. 1943) (01.11.1999)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.1999)
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Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection
GHIARA, P, ROSSI, M, RAPPUOLI, R, DEL GIUDICE, G, MARCHETTI, M, DI TOMMASO, A, VINDIGNI, C, CIAMPOLINI, F, COVACCI, A, TELFORD, J. L, DE MAGISTRIS, M. T, PIZZA, M
Published in Infection and Immunity (01.12.1997)
Published in Infection and Immunity (01.12.1997)
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Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin
Papini, E, Satin, B, Norais, N, de Bernard, M, Telford, J L, Rappuoli, R, Montecucco, C
Published in The Journal of clinical investigation (15.08.1998)
Published in The Journal of clinical investigation (15.08.1998)
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Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies
MANETTI, R, MASSARI, P, BURRONI, D, DE BERNARD, M, MARCHINI, A, OLIVIERI, R, PAPINI, E, MONTECUCCO, C, RAPPUOLI, R, TELFORD, J. L
Published in Infection and Immunity (01.11.1995)
Published in Infection and Immunity (01.11.1995)
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Binding of the Helicobacter pylori vacuolating cytotoxin to target cells
MASSARI, P, MANETTI, R, BURRONI, D, NUTI, S, NORAIS, N, RAPPUOLI, R, TELFORD, J. L
Published in Infection and immunity (01.08.1998)
Published in Infection and immunity (01.08.1998)
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Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
Marchetti, Marta, Rossi, Michela, Giannelli, Valentina, Giuliani, Marzia M, Pizza, Mariagrazia, Censini, Stefano, Covacci, Antonello, Massari, Paola, Pagliaccia, Cristina, Manetti, Roberto, Telford, John L, Douce, Gill, Dougan, Gordon, Rappuoli, Rino, Ghiara, Paolo
Published in Vaccine (1998)
Published in Vaccine (1998)
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Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity
Pelicic, Vladimir, Reyrat, Jean-Marc, Sartori, Lucia, Pagliaccia, Cristina, Rappuoli, Rino, Telford, John L, Montecucco, Cesare, Papini, Emanuele
Published in Microbiology (Society for General Microbiology) (01.08.1999)
Published in Microbiology (Society for General Microbiology) (01.08.1999)
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A structural overview of the Helicobacter cytotoxin
Reyrat, J.-M., Rappuoli, R., Telford, J.L.
Published in International journal of medical microbiology (01.10.2000)
Published in International journal of medical microbiology (01.10.2000)
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The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms
Boncristiano, Marianna, Paccani, Silvia Rossi, Barone, Silvia, Ulivieri, Cristina, Patrussi, Laura, Ilver, Dag, Amedei, Amedeo, D'Elios, Mario Milco, Telford, John L, Baldari, Cosima T
Published in The Journal of experimental medicine (15.12.2003)
Published in The Journal of experimental medicine (15.12.2003)
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ras protein activity is essential for T-cell antigen receptor signal transduction
BALDARI, C. T, HEGUY, A, TELFORD, J. L
Published in The Journal of biological chemistry (05.02.1993)
Published in The Journal of biological chemistry (05.02.1993)
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Detoxification of the Helicobacter pylori cytotoxin
MANETTI, R, MASSARI, P, MARCHETTI, M, MAGAGNOLI, C, NUTI, S, LUPETTI, P, GHIARA, P, RAPPUOLI, R, TELFORD, J. L
Published in Infection and Immunity (01.11.1997)
Published in Infection and Immunity (01.11.1997)
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Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: Potential new therapies and vaccines
Telford, John L., Covacci, Antonello, Ghiara, Paolo, Montecucco, Cesare, Rappuoli, Rino
Published in Trends in Biotechnology (01.10.1994)
Published in Trends in Biotechnology (01.10.1994)
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Interleukin-2 promoter activation in T-cells expressing activated Ha-ras
BALDARI, C. T, MACCHIA, G, TELFORD, J. L
Published in The Journal of biological chemistry (05.03.1992)
Published in The Journal of biological chemistry (05.03.1992)
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