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Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
Nelson, Peter T, Dickson, Dennis W, Trojanowski, John Q, Jack, Clifford R, Boyle, Patricia A, Arfanakis, Konstantinos, Rademakers, Rosa, Alafuzoff, Irina, Attems, Johannes, Brayne, Carol, Coyle-Gilchrist, Ian T S, Chui, Helena C, Fardo, David W, Flanagan, Margaret E, Halliday, Glenda, Hokkanen, Suvi R K, Hunter, Sally, Jicha, Gregory A, Katsumata, Yuriko, Kawas, Claudia H, Keene, C Dirk, Kovacs, Gabor G, Kukull, Walter A, Levey, Allan I, Makkinejad, Nazanin, Montine, Thomas J, Murayama, Shigeo, Murray, Melissa E, Nag, Sukriti, Rissman, Robert A, Seeley, William W, Sperling, Reisa A, White III, Charles L, Yu, Lei, Schneider, Julie A
Published in Brain (London, England : 1878) (01.06.2019)
Published in Brain (London, England : 1878) (01.06.2019)
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TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia
James, Bryan D., Wilson, Robert S., Boyle, Patricia A., Trojanowski, John Q., Bennett, David A., Schneider, Julie A.
Published in Brain (London, England : 1878) (01.11.2016)
Published in Brain (London, England : 1878) (01.11.2016)
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TDP-43 is a key player in the clinical features associated with Alzheimer’s disease
Josephs, Keith A., Whitwell, Jennifer L., Weigand, Stephen D., Murray, Melissa E., Tosakulwong, Nirubol, Liesinger, Amanda M., Petrucelli, Leonard, Senjem, Matthew L., Knopman, David S., Boeve, Bradley F., Ivnik, Robert J., Smith, Glenn E., Jack, Clifford R., Parisi, Joseph E., Petersen, Ronald C., Dickson, Dennis W.
Published in Acta neuropathologica (01.06.2014)
Published in Acta neuropathologica (01.06.2014)
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The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity
Wang, Wenzhang, Wang, Luwen, Lu, Junjie, Siedlak, Sandra L, Fujioka, Hisashi, Liang, Jingjing, Jiang, Sirui, Ma, Xiaopin, Jiang, Zhen, da Rocha, Edroaldo Lummertz, Sheng, Max, Choi, Heewon, Lerou, Paul H, Li, Hu, Wang, Xinglong
Published in Nature medicine (01.08.2016)
Published in Nature medicine (01.08.2016)
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TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates
Laferrière, Florent, Maniecka, Zuzanna, Pérez-Berlanga, Manuela, Hruska-Plochan, Marian, Gilhespy, Larissa, Hock, Eva-Maria, Wagner, Ulrich, Afroz, Tariq, Boersema, Paul J., Barmettler, Gery, Foti, Sandrine C., Asi, Yasmine T., Isaacs, Adrian M., Al-Amoudi, Ashraf, Lewis, Amanda, Stahlberg, Henning, Ravits, John, De Giorgi, Francesca, Ichas, François, Bezard, Erwan, Picotti, Paola, Lashley, Tammaryn, Polymenidou, Magdalini
Published in Nature neuroscience (01.01.2019)
Published in Nature neuroscience (01.01.2019)
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TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer’s disease and frontotemporal lobar degeneration
Foulds, Penelope, McAuley, Erica, Gibbons, Linda, Davidson, Yvonne, Pickering-Brown, Stuart M., Neary, David, Snowden, Julie S., Allsop, David, Mann, David M. A.
Published in Acta neuropathologica (01.08.2008)
Published in Acta neuropathologica (01.08.2008)
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The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels
Salazar, D. A., Butler, V. J., Argouarch, A. R., Hsu, T.-Y., Mason, A., Nakamura, A., McCurdy, H., Cox, D., Ng, R., Pan, G., Seeley, W. W., Miller, B. L., Kao, A. W.
Published in The Journal of neuroscience (24.06.2015)
Published in The Journal of neuroscience (24.06.2015)
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Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy
Katsumata, Yuriko, Abner, Erin L., Karanth, Shama, Teylan, Merilee A., Mock, Charles N., Cykowski, Matthew D., Lee, Edward B., Boehme, Kevin L., Mukherjee, Shubhabrata, Kauwe, John S. K., Kryscio, Richard J., Schmitt, Frederick A., Fardo, David W., Nelson, Peter T.
Published in Acta neuropathologica (01.11.2020)
Published in Acta neuropathologica (01.11.2020)
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Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
Tollervey, James R, Curk, Tomaž, Rogelj, Boris, Briese, Michael, Cereda, Matteo, Kayikci, Melis, König, Julian, Hortobágyi, Tibor, Nishimura, Agnes L, Župunski, Vera, Patani, Rickie, Chandran, Siddharthan, Rot, Gregor, Zupan, Blaž, Shaw, Christopher E, Ule, Jernej
Published in Nature neuroscience (01.04.2011)
Published in Nature neuroscience (01.04.2011)
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The phosphatase calcineurin regulates pathological TDP-43 phosphorylation
Liachko, Nicole F., Saxton, Aleen D., McMillan, Pamela J., Strovas, Timothy J., Currey, Heather N., Taylor, Laura M., Wheeler, Jeanna M., Oblak, Adrian L., Ghetti, Bernardino, Montine, Thomas J., Keene, C. Dirk, Raskind, Murray A., Bird, Thomas D., Kraemer, Brian C.
Published in Acta neuropathologica (01.10.2016)
Published in Acta neuropathologica (01.10.2016)
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Novel tankyrase inhibitors suppress TDP-43 aggregate formation
Tanji, Kunikazu, Mori, Fumiaki, Shirai, Fumiyuki, Fukami, Takehiro, Seimiya, Hiroyuki, Utsumi, Jun, Kakita, Akiyoshi, Wakabayashi, Koichi
Published in Biochemical and biophysical research communications (22.01.2021)
Published in Biochemical and biophysical research communications (22.01.2021)
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Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer’s disease neuropathologic changes and cognitive decline
Chang, Koping, Ling, Jonathan P., Redding-Ochoa, Javier, An, Yang, Li, Ling, Dean, Stephanie A., Blanchard, Thomas G., Pylyukh, Tatiana, Barrett, Alexander, Irwin, Katherine E., Moghekar, Abhay, Resnick, Susan M., Wong, Philip C., Troncoso, Juan C.
Published in Acta neuropathologica (01.06.2024)
Published in Acta neuropathologica (01.06.2024)
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TDP-43 CSF Concentrations Increase Exponentially with Age in Metropolitan Mexico City Young Urbanites Highly Exposed to PM2.5 and Ultrafine Particles and Historically Showing Alzheimer and Parkinson’s Hallmarks. Brain TDP-43 Pathology in MMC Residents Is Associated with High Cisternal CSF TDP-43 Concentrations
Calderón-Garcidueñas, Lilian, Stommel, Elijah W., Lachmann, Ingolf, Waniek, Katharina, Chao, Chih-Kai, González-Maciel, Angélica, García-Rojas, Edgar, Torres-Jardón, Ricardo, Delgado-Chávez, Ricardo, Mukherjee, Partha S.
Published in Toxics (Basel) (24.09.2022)
Published in Toxics (Basel) (24.09.2022)
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Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration
Bejanin, Alexandre, Murray, Melissa E, Martin, Peter, Botha, Hugo, Tosakulwong, Nirubol, Schwarz, Christopher G, Senjem, Matthew L, Chételat, Gael, Kantarci, Kejal, Jack, Clifford R, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Giannini, Caterina, Parisi, Joseph E, Dickson, Dennis W, Whitwell, Jennifer L, Josephs, Keith A
Published in Brain (London, England : 1878) (01.11.2019)
Published in Brain (London, England : 1878) (01.11.2019)
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Limbic-predominant age-related TDP-43 encephalopathy in the oldest old: a population-based study
Mikhailenko, Elizaveta, Colangelo, Kia, Tuimala, Jarno, Kero, Mia, Savola, Sara, Raunio, Anna, Kok, Eloise H, Tanskanen, Maarit, Mäkelä, Mira, Puttonen, Henri, Mäyränpää, Mikko I, Kumar, Darshan, Kaivola, Karri, Paetau, Anders, Tienari, Pentti J, Polvikoski, Tuomo, Myllykangas, Liisa
Published in Brain (London, England : 1878) (07.01.2025)
Published in Brain (London, England : 1878) (07.01.2025)
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Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease
Nag, Sukriti, Yu, Lei, Capuano, Ana W., Wilson, Robert S., Leurgans, Sue E., Bennett, David A., Schneider, Julie A.
Published in Annals of neurology (01.06.2015)
Published in Annals of neurology (01.06.2015)
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Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration
Kellett, Elise A., Bademosi, Adekunle T., Walker, Adam K.
Published in Molecular neurodegeneration (08.05.2025)
Published in Molecular neurodegeneration (08.05.2025)
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Transactive response DNA-binding protein 43 (TDP-43) proteinopathy: the complex biological and clinical findings in limbic-predominant age-related TDP-43 encephalopathy (LATE) neuropathological changes, limbic-predominant amnestic neurodegenerative syndrome, and other mixed age-related major neurocognitive disorders
Radanovic, Marcia, Passos Neto, Carlos Eduardo Borges, Monteiro, Luiz Henrique, Forlenza, Orestes Vicente
Published in Current opinion in psychiatry (01.09.2025)
Published in Current opinion in psychiatry (01.09.2025)
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