Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson′s Disease
Coku, Ilda, Mutez, Eugénie, Eddarkaoui, Sabiha, Carrier, Sébastien, Marchand, Antoine, Deldycke, Claire, Goveas, Liesel, Baille, Guillaume, Tir, Mélissa, Magnez, Romain, Thuru, Xavier, Vermeersch, Gaëlle, Vandenberghe, Wim, Buée, Luc, Defebvre, Luc, Sablonnière, Bernard, Chartier‐Harlin, Marie‐Christine, Taymans, Jean‐Marc, Huin, Vincent
Published in Movement disorders (01.08.2022)
Published in Movement disorders (01.08.2022)
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MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein
Cho, Hyun Jin, Liu, Guoxiang, Jin, Seok Min, Parisiadou, Loukia, Xie, Chengsong, Yu, Jia, Sun, Lixin, Ma, Bo, Ding, Jinhui, Vancraenenbroeck, Renée, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, He, Ping, Troncoso, Juan C, Shen, Yong, Cai, Huaibin
Published in Human molecular genetics (01.02.2013)
Published in Human molecular genetics (01.02.2013)
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Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
Parisiadou, Loukia, Xie, Chengsong, Cho, Hyun Jin, Lin, Xian, Gu, Xing-Long, Long, Cai-Xia, Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc, Sun, Lixin, Cai, Huaibin
Published in The Journal of neuroscience (04.11.2009)
Published in The Journal of neuroscience (04.11.2009)
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Journal Article
LRRK2 Phosphorylation, More Than an Epiphenomenon
Marchand, Antoine, Drouyer, Matthieu, Sarchione, Alessia, Chartier-Harlin, Marie-Christine, Taymans, Jean-Marc
Published in Frontiers in neuroscience (16.06.2020)
Published in Frontiers in neuroscience (16.06.2020)
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Journal Article
Distribution of PINK1 and LRRK2 in rat and mouse brain
Taymans, Jean‐Marc, Van den Haute, Chris, Baekelandt, Veerle
Published in Journal of neurochemistry (01.08.2006)
Published in Journal of neurochemistry (01.08.2006)
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Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain
Civiero, Laura, Cirnaru, Maria Daniela, Beilina, Alexandra, Rodella, Umberto, Russo, Isabella, Belluzzi, Elisa, Lobbestael, Evy, Reyniers, Lauran, Hondhamuni, Geshanthi, Lewis, Patrick A., Van den Haute, Chris, Baekelandt, Veerle, Bandopadhyay, Rina, Bubacco, Luigi, Piccoli, Giovanni, Cookson, Mark R., Taymans, Jean‐Marc, Greggio, Elisa
Published in Journal of neurochemistry (01.12.2015)
Published in Journal of neurochemistry (01.12.2015)
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Automated quantitative gait analysis in animal models of movement disorders
Vandeputte, Caroline, Taymans, Jean-Marc, Casteels, Cindy, Coun, Frea, Ni, Yicheng, Van Laere, Koen, Baekelandt, Veerle
Published in BMC neuroscience (09.08.2010)
Published in BMC neuroscience (09.08.2010)
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The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation
Greggio, Elisa, Zambrano, Ibardo, Kaganovich, Alice, Beilina, Alexandra, Taymans, Jean-Marc, Daniëls, Veronique, Lewis, Patrick, Jain, Shushant, Ding, Jinhui, Syed, Ali, Thomas, Kelly J., Baekelandt, Veerle, Cookson, Mark R.
Published in The Journal of biological chemistry (13.06.2008)
Published in The Journal of biological chemistry (13.06.2008)
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Journal Article
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
Lobbestael, Evy, Zhao, Jing, Rudenko, Iakov N, Beylina, Aleksandra, Gao, Fangye, Wetter, Justin, Beullens, Monique, Bollen, Mathieu, Cookson, Mark R, Baekelandt, Veerle, Nichols, R Jeremy, Taymans, Jean-Marc
Published in Biochemical journal (15.11.2013)
Published in Biochemical journal (15.11.2013)
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Journal Article
Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes
Sejwal, Kushal, Chami, Mohamed, Rémigy, Hervé, Vancraenenbroeck, Renée, Sibran, William, Sütterlin, Rosmarie, Baumgartner, Paul, McLeod, Robert, Chartier-Harlin, Marie-Christine, Baekelandt, Veerle, Stahlberg, Henning, Taymans, Jean-Marc
Published in Scientific reports (17.08.2017)
Published in Scientific reports (17.08.2017)
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Journal Article
Perspective on the current state of the LRRK2 field
Taymans, Jean-Marc, Fell, Matt, Greenamyre, Tim, Hirst, Warren D, Mamais, Adamantios, Padmanabhan, Shalini, Peter, Inga, Rideout, Hardy, Thaler, Avner
Published in NPJ Parkinson's Disease (01.07.2023)
Published in NPJ Parkinson's Disease (01.07.2023)
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Journal Article
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
Daniëls, Veronique, Vancraenenbroeck, Renée, Law, Bernard M. H., Greggio, Elisa, Lobbestael, Evy, Gao, Fangye, De Maeyer, Marc, Cookson, Mark R., Harvey, Kirsten, Baekelandt, Veerle, Taymans, Jean‐Marc
Published in Journal of neurochemistry (01.01.2011)
Published in Journal of neurochemistry (01.01.2011)
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Journal Article
Phosphorylation of LRRK2: from kinase to substrate
Lobbestael, Evy, Baekelandt, Veerle, Taymans, Jean-Marc
Published in Biochemical Society transactions (01.10.2012)
Published in Biochemical Society transactions (01.10.2012)
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Journal Article
Alpha-Synuclein and Lipids: The Elephant in the Room?
Sarchione, Alessia, Marchand, Antoine, Taymans, Jean-Marc, Chartier-Harlin, Marie-Christine
Published in Cells (Basel, Switzerland) (17.09.2021)
Published in Cells (Basel, Switzerland) (17.09.2021)
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Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers
Civiero, Laura, Vancraenenbroeck, Renée, Belluzzi, Elisa, Beilina, Alexandra, Lobbestael, Evy, Reyniers, Lauran, Gao, Fangye, Micetic, Ivan, De Maeyer, Marc, Bubacco, Luigi, Baekelandt, Veerle, Cookson, Mark R, Greggio, Elisa, Taymans, Jean-Marc
Published in PloS one (29.08.2012)
Published in PloS one (29.08.2012)
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