DNA Unwinding Is the Primary Determinant of CRISPR-Cas9 Activity
Gong, Shanzhong, Yu, Helen Hong, Johnson, Kenneth A., Taylor, David W.
Published in Cell reports (Cambridge) (09.01.2018)
Published in Cell reports (Cambridge) (09.01.2018)
Get full text
Journal Article
Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
Zhou, Yi, Musalgaonkar, Sharmishtha, Johnson, Arlen W., Taylor, David W.
Published in Nature communications (27.02.2019)
Published in Nature communications (27.02.2019)
Get full text
Journal Article
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
Jiang, Fuguo, Taylor, David W., Chen, Janice S., Kornfeld, Jack E., Zhou, Kaihong, Thompson, Aubri J., Nogales, Eva, Doudna, Jennifer A.
Published in Science (American Association for the Advancement of Science) (19.02.2016)
Published in Science (American Association for the Advancement of Science) (19.02.2016)
Get full text
Journal Article
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
Jinek, Martin, Jiang, Fuguo, Taylor, David W., Sternberg, Samuel H., Kaya, Emine, Ma, Enbo, Anders, Carolin, Hauer, Michael, Zhou, Kaihong, Lin, Steven, Kaplan, Matias, Iavarone, Anthony T., Charpentier, Emmanuelle, Nogales, Eva, Doudna, Jennifer A.
Published in Science (American Association for the Advancement of Science) (14.03.2014)
Published in Science (American Association for the Advancement of Science) (14.03.2014)
Get full text
Journal Article
CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference
Hochstrasser, Megan L., Taylor, David W., Bhata, Prashant, Guegler, Chantal K., Sternberg, Samuel H., Nogales, Eva, Doudna, Jennifer A.
Published in Proceedings of the National Academy of Sciences - PNAS (06.05.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (06.05.2014)
Get full text
Journal Article
A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity
Cifuentes, Daniel, Xue, Huiling, Taylor, David W., Patnode, Heather, Mishima, Yuichiro, Cheloufi, Sihem, Ma, Enbo, Mane, Shrikant, Hannon, Gregory J., Lawson, Nathan D., Wolfe, Scot A., Giraldez, Antonio J.
Published in Science (American Association for the Advancement of Science) (25.06.2010)
Published in Science (American Association for the Advancement of Science) (25.06.2010)
Get full text
Journal Article
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
Taylor, David W., Zhu, Yifan, Staals, Raymond H. J., Kornfeld, Jack E., Shinkai, Akeo, van der Oost, John, Nogales, Eva, Doudna, Jennifer A.
Published in Science (American Association for the Advancement of Science) (01.05.2015)
Published in Science (American Association for the Advancement of Science) (01.05.2015)
Get full text
Journal Article
The microbiota and helminths: sharing the same niche in the human host
GLENDINNING, LAURA, NAUSCH, NORMAN, FREE, ANDREW, TAYLOR, DAVID W., MUTAPI, FRANCISCA
Published in Parasitology (01.09.2014)
Published in Parasitology (01.09.2014)
Get full text
Journal Article
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation
Steens, Jurre A., Zhu, Yifan, Taylor, David W., Bravo, Jack P. K., Prinsen, Stijn H. P., Schoen, Cor D., Keijser, Bart J. F., Ossendrijver, Michel, Hofstra, L. Marije, Brouns, Stan J. J., Shinkai, Akeo, van der Oost, John, Staals, Raymond H. J.
Published in Nature communications (19.08.2021)
Published in Nature communications (19.08.2021)
Get full text
Journal Article
An RNA Degradation Machine Sculpted by Ro Autoantigen and Noncoding RNA
Chen, Xinguo, Taylor, David W., Fowler, Casey C., Galan, Jorge E., Wang, Hong-Wei, Wolin, Sandra L.
Published in Cell (28.03.2013)
Published in Cell (28.03.2013)
Get full text
Journal Article
Structural basis for broad anti-phage immunity by DISARM
Bravo, Jack P. K., Aparicio-Maldonado, Cristian, Nobrega, Franklin L., Brouns, Stan J. J., Taylor, David W.
Published in Nature communications (27.05.2022)
Published in Nature communications (27.05.2022)
Get full text
Journal Article
Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells
Katawa, Gnatoulma, Layland, Laura E, Debrah, Alex Y, von Horn, Charlotte, Batsa, Linda, Kwarteng, Alexander, Arriens, Sandra, W Taylor, David, Specht, Sabine, Hoerauf, Achim, Adjobimey, Tomabu
Published in PLoS neglected tropical diseases (01.01.2015)
Published in PLoS neglected tropical diseases (01.01.2015)
Get full text
Journal Article
Integrative modeling reveals the molecular architecture of the intraflagellar transport A (IFT-A) complex
McCafferty, Caitlyn L, Papoulas, Ophelia, Jordan, Mareike A, Hoogerbrugge, Gabriel, Nichols, Candice, Pigino, Gaia, Taylor, David W, Wallingford, John B, Marcotte, Edward M
Published in eLife (08.11.2022)
Published in eLife (08.11.2022)
Get full text
Journal Article
Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9
Hibshman, Grace N., Bravo, Jack P. K., Hooper, Matthew M., Dangerfield, Tyler L., Zhang, Hongshan, Finkelstein, Ilya J., Johnson, Kenneth A., Taylor, David W.
Published in Nature communications (30.04.2024)
Published in Nature communications (30.04.2024)
Get full text
Journal Article