Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases
Steinig, Arno G., Li, An-Hu, Wang, Jing, Chen, Xin, Dong, Hanqing, Ferraro, Caterina, Jin, Meizhong, Kadalbajoo, Mridula, Kleinberg, Andrew, Stolz, Kathryn M., Tavares-Greco, Paula A., Wang, Ti, Albertella, Mark R., Peng, Yue, Crew, Linda, Kahler, Jennifer, Kan, Julie, Schulz, Ryan, Cooke, Andy, Bittner, Mark, Turton, Roy W., Franklin, Maryland, Gokhale, Prafulla, Landfair, Darla, Mantis, Christine, Workman, Jen, Wild, Robert, Pachter, Jonathan, Epstein, David, Mulvihill, Mark J.
Published in Bioorganic & medicinal chemistry letters (01.08.2013)
Published in Bioorganic & medicinal chemistry letters (01.08.2013)
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Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1)
Kanouni, Toufike, Severin, Christophe, Cho, Robert W, Yuen, Natalie Y.-Y, Xu, Jiangchun, Shi, Lihong, Lai, Chon, Del Rosario, Joselyn R, Stansfield, Ryan K, Lawton, Lee N, Hosfield, David, O’Connell, Shawn, Kreilein, Matt M, Tavares-Greco, Paula, Nie, Zhe, Kaldor, Stephen W, Veal, James M, Stafford, Jeffrey A, Chen, Young K
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
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Imidazo[1,5- a]pyrazines: Orally efficacious inhibitors of mTORC1 and mTORC2
Crew, Andrew P., Bhagwat, Shripad V., Dong, Hanqing, Bittner, Mark A., Chan, Anna, Chen, Xin, Coate, Heather, Cooke, Andrew, Gokhale, Prafulla C., Honda, Ayako, Jin, Meizhong, Kahler, Jennifer, Mantis, Christine, Mulvihill, Mark J., Tavares-Greco, Paula A., Volk, Brian, Wang, Jing, Werner, Douglas S., Arnold, Lee D., Pachter, Jonathan A., Wild, Robert, Gibson, Neil W.
Published in Bioorganic & medicinal chemistry letters (01.04.2011)
Published in Bioorganic & medicinal chemistry letters (01.04.2011)
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(S)-2-이소인돌린-1,3-디온의제조 프로세스
FERRETTI ANTONIO C, LIU WEI, DUNN ROBERT FRANCIS, CORONA PATRICK, RANGANATHAN KRISHNAKUMAR, PURDUM GEOFFREY EUGENE, DEL VALLE DAVID, HEID RICHARD MARTIN, YONG KELVIN HIN YEONG, TAVARES GRECO PAULA A, CHEN JIAN, KASSIM AMUDE, YU YONG, KOTHARE MOHIT, CARRASQUILLO FLORES RONALD, ZHANG CHENGMIN, EMMANUEL MEGAN
Year of Publication 23.02.2024
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Year of Publication 23.02.2024
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(S)-4--3-플루오로벤조니트릴을 포함하는 고체 형태 및 이의 염, 그리고 이를 포함하는 조성물 및 이의 사용 방법
FERRETTI ANTONIO C, JAIN UDAYKUMAR, HUANG LIANFENG, TAVARES GRECO PAULA A, WU WENJU, ARTMAN III GERALD D, YIN ZHIWEI, TSOU NANCY NIENHUA, MAN HON WAH
Year of Publication 18.10.2021
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Year of Publication 18.10.2021
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항증식성 화합물 및 이의 사용 방법
CARMICHAEL JAMES, ALEXANDER MATTHEW D, CARRANCIO SORAYA, CATHERS BRIAN E, CORREA MATTHEW D, WHITEFIELD BRANDON W, LOPEZ GIRONA ANTONIA, BRAY GORDON L, KERCHER TIMOTHY S, ARTMAN GERALD D. III, HANSEN JOSHUA, ZOU NANFEI, PICCOTTI JOSEPH R, NARLA RAMA K, TAVARES GRECO PAULA A, PIERCE DANIEL W, WONG LILLY L, NAGY MARK A, MAN HON WAH, HAVENS COURTNEY G, LU XIAOLING
Year of Publication 11.03.2020
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Year of Publication 11.03.2020
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PREPARATION OF C-PYRAZINE-METHYLAMINES
MULVIHILL KRISTEN MICHELLE, MAO YUNYU, TAVARES GRECO PAULA A, RECHKA JOSEF A
Year of Publication 07.03.2012
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Year of Publication 07.03.2012
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Synthetic approaches to 5,7-disubstituted imidazo[5,1- f][1,2,4]triazin-4-amines
Werner, Douglas S., Dong, Hanqing, Kadalbajoo, Mridula, Laufer, Radoslaw S., Tavares-Greco, Paula A., Volk, Brian R., Mulvihill, Mark J., Crew, Andrew P.
Published in Tetrahedron letters (28.07.2010)
Published in Tetrahedron letters (28.07.2010)
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Abstract 2915: Discovery and characterization of OSI-296, a dual inhibitor of cMET and RON kinases
Steinig, Arno G., Li, An-Hu, Wang, Jing, Kleinberg, Andrew, Dong, Hanqing, Wang, Ti, Gavagan, Kathryn M. Stolz, Jin, Meizhong, Tavares-Greco, Paula, Peng, Yue, Kahler, Jen, Castaldo, Linda, McCormack, Siobhan, Kan, Julie, Albertella, Mark, Cooke, Andy, Turton, Roy, Bittner, Mark, Franklin, Maryland, Landfair, Darla, Gokhale, Prafulla, Wild, Robert, Pachter, Jonathan, Epstein, David, Mulvihill, Mark J.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE
TAVARES-GRECO, Paula, CARRASQUILLO-FLORES, Ronald, KOTHARE, Mohit, DEL VALLE, David, PURDUM, Geoffrey, HEID, Richard, LIU, Wei, KASSIM, Amude, CORONA, Patrick, EMMANUEL, Megan, YONG, Kelvin, FERRETTI, Antonio, CHEN, Jian, DUNN, Robert, ZHANG, Chengmin, RANGANATHAN, Krishnakumar, YU, Yong
Year of Publication 16.11.2023
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Year of Publication 16.11.2023
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4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND
TAVARES-GRECO, Paula, A, KERCHER, Timothy, S, PICCOTTI, Joseph, R, NARLA, Rama, K, WONG, Lilly, L, CORREA, Matthew, D, LOPEZ-GIRONA, Antonia, CARMICHAEL, James, PIERCE, Daniel, W, BRAY, Gordon, L, ARTMAN, Gerald, D., III, LU, Xiaoling, HANSEN, Joshua, CATHERS, Brian E, CARRANCIO, Soraya, NAGY, Mark, A, MAN, Hon-Wah, HAVENS, Courtney, G, ALEXANDER, Matthew, D, WHITEFIELD, Brandon, W, ZOU, Nanfei
Year of Publication 11.09.2024
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Year of Publication 11.09.2024
Patent
SOLID FORMS COMPRISING (S)-4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-1-YL)-3-FLUOROBENZONITRILE AND SALTS THEREOF, AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME
Ferretti, Antonio C, Tsou, Nancy Nienhua, Yin, Zhiwei, Huang, Lianfeng, Wu, Wenju, Artman, III, Gerald D, Man, Hon-Wah, Jain, Udaykumar, Tavares-Greco, Paula A
Year of Publication 15.09.2022
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Year of Publication 15.09.2022
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PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL)METHYL)BENZYL)AMINO)ISOINDOLINE-1,3-DIONE
TAVARES-GRECO, Paula A, CARRASQUILLO-FLORES, Ronald, KOTHARE, Mohit, DEL VALLE, David, PURDUM, Geoffrey Eugene, DUNN, Robert Francis, FERRETTI, Antonio C, LIU, Wei, KASSIM, Amude, CORONA, Patrick, EMMANUEL, Megan, HEID, Richard Martin, CHEN, Jian, YONG, Kelvin Hin-Yeong, ZHANG, Chengmin, RANGANATHAN, Krishnakumar, YU, Yong
Year of Publication 11.07.2024
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Year of Publication 11.07.2024
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Antiproliferative compounds and methods of use thereof
Pierce, Daniel W, Hansen, Joshua, Lopez-Girona, Antonia, Piccotti, Joseph R, Zou, Nanfei, Whitefield, Brandon W, Artman, Gerald D, Carmichael, James, Lu, Xiaoling, Wong, Lilly L, Bray, Gordon L, Carrancio, Soraya, Cathers, Brian E, Kercher, Timothy S, Correa, Matthew D, Narla, Rama K, Nagy, Mark A, Havens, Courtney G, Alexander, Matthew D, Man, Hon-Wah, Tavares-Greco, Paula A
Year of Publication 09.07.2024
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Year of Publication 09.07.2024
Patent
ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF
Pierce, Daniel W, Hansen, Joshua, Lopez-Girona, Antonia, Piccotti, Joseph R, Zou, Nanfei, Whitefield, Brandon W, Artman, Gerald D, Carmichael, James, Lu, Xiaoling, Wong, Lilly L, Bray, Gordon L, Cathers, Brian E, Kercher, Timothy S, Correa, Matthew D, Carranico, Soraya, Narla, Rama K, Nagy, Mark A, Havens, Courtney G, Alexander, Matthew D, Man, Hon-Wah, Tavares-Greco, Paula A
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
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Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same
Ferretti, Antonio C, Tsou, Nancy Nienhua, Yin, Zhiwei, Huang, Lianfeng, Wu, Wenju, Artman, III, Gerald D, Man, Hon-Wah, Jain, Udaykumar, Tavares-Greco, Paula A
Year of Publication 28.06.2022
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Year of Publication 28.06.2022
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PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE
TAVARES-GRECO, Paula, A, CARRASQUILLO-FLORES, Ronald, YONG, Kelvin, Hin-yeong, KOTHARE, Mohit, DUNN, Robert, Francis, DEL VALLE, David, HEID, Richard, Martin, LIU, Wei, KASSIM, Amude, CORONA, Patrick, EMMANUEL, Megan, CHEN, Jian, FERRETTI, Antonio, C, PURDUM, Geoffrey, Eugene, ZHANG, Chengmin, RANGANATHAN, Krishnakumar, YU, Yong
Year of Publication 01.05.2024
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Year of Publication 01.05.2024
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PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE
TAVARES-GRECO, Paula, CARRASQUILLO-FLORES, Ronald, KOTHARE, Mohit, DEL VALLE, David, PURDUM, Geoffrey, HEID, Richard, LIU, Wei, KASSIM, Amude, CORONA, Patrick, EMMANUEL, Megan, YONG, Kelvin, FERRETTI, Antonio, CHEN, Jian, DUNN, Robert, ZHANG, Chengmin, RANGANATHAN, Krishnakumar, YU, Yong
Year of Publication 29.12.2022
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Year of Publication 29.12.2022
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Processes for the preparation of (s)-2-(2,6-dioxopiperidin-3-yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl) methyl)benzyl) amino)isoindoline-1,3-dione
EMMANUEL Megan, CHEN Jian, KASSIM Amude, DUNN Robert Francis, CARRASQUILLO-FLORES Ronald, TAVARES-GRECO Paula A, YU Yong, FERRETTI Antonio C, ZHANG Chengmin, CORONA Patrick, LIU Wei, DEL VALLE David, PURDUM Geoffrey Eugene, KOTHARE Mohit, YONG Kelvin Hin-yeong, HEID Richard Martin, RANGANATHAN Krishnakumar
Year of Publication 01.12.2023
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Year of Publication 01.12.2023
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