AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson’s Disease
Balke, Dirk, Tatenhorst, Lars, Dambeck, Vivian, Ribas, Vinicius Toledo, Vahsen, Björn F., Michel, Uwe, Bähr, Mathias, Lingor, Paul
Published in Molecular neurobiology (01.02.2020)
Published in Molecular neurobiology (01.02.2020)
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Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing
Vahsen, Björn Friedhelm, Ribas, Vinicius Toledo, Sundermeyer, Jonas, Boecker, Alexander, Dambeck, Vivian, Lenz, Christof, Shomroni, Orr, Caldi Gomes, Lucas, Tatenhorst, Lars, Barski, Elisabeth, Roser, Anna-Elisa, Michel, Uwe, Urlaub, Henning, Salinas, Gabriela, Bähr, Mathias, Koch, Jan Christoph, Lingor, Paul
Published in Cell death and differentiation (01.10.2020)
Published in Cell death and differentiation (01.10.2020)
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Journal Article
Increased alpha-synuclein tear fluid levels in patients with Parkinson’s disease
Maass, Fabian, Rikker, Sebastian, Dambeck, Vivian, Warth, Carmina, Tatenhorst, Lars, Csoti, Ilona, Schmitz, Matthias, Zerr, Inga, Leha, Andreas, Bähr, Mathias, Lingor, Paul
Published in Scientific reports (22.05.2020)
Published in Scientific reports (22.05.2020)
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Journal Article
AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo
Ribas, Vinicius Toledo, Vahsen, Björn Friedhelm, Tatenhorst, Lars, Estrada, Veronica, Dambeck, Vivian, Almeida, Raquel Alves, Bähr, Mathias, Michel, Uwe, Koch, Jan Christoph, Müller, Hans Werner, Lingor, Paul
Published in Cell death & disease (26.02.2021)
Published in Cell death & disease (26.02.2021)
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Journal Article
TREM2 regulates microglial lipid droplet formation and represses post-ischemic brain injury
Wei, Wei, Zhang, Lin, Xin, Wenqiang, Pan, Yongli, Tatenhorst, Lars, Hao, Zhongnan, Gerner, Stefan T., Huber, Sabine, Juenemann, Martin, Butz, Marius, Huttner, Hagen B., Bähr, Mathias, Fitzner, Dirk, Jia, Feng, Doeppner, Thorsten R.
Published in Biomedicine & pharmacotherapy (01.01.2024)
Published in Biomedicine & pharmacotherapy (01.01.2024)
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Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice
Vingill, Siv, Brockelt, David, Lancelin, Camille, Tatenhorst, Lars, Dontcheva, Guergana, Preisinger, Christian, Schwedhelm-Domeyer, Nicola, Joseph, Sabitha, Mitkovski, Miso, Goebbels, Sandra, Nave, Klaus-Armin, Schulz, Jörg B, Marquardt, Till, Lingor, Paul, Stegmüller, Judith
Published in The EMBO journal (15.09.2016)
Published in The EMBO journal (15.09.2016)
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Journal Article
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
Saal, Kim-Ann, Koch, Jan C, Tatenhorst, Lars, Szegő, Éva M, Ribas, Vinicius Toledo, Michel, Uwe, Bähr, Mathias, Tönges, Lars, Lingor, Paul
Published in Neurobiology of disease (01.01.2015)
Published in Neurobiology of disease (01.01.2015)
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Journal Article
Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein
Martinez Hernandez, Ana, Silbern, Ivan, Geffers, Insa, Tatenhorst, Lars, Becker, Stefan, Urlaub, Henning, Zweckstetter, Markus, Griesinger, Christian, Eichele, Gregor
Published in Frontiers in neuroscience (17.06.2021)
Published in Frontiers in neuroscience (17.06.2021)
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miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons
Roser, Anna-Elisa, Caldi Gomes, Lucas, Halder, Rashi, Jain, Gaurav, Maass, Fabian, Tönges, Lars, Tatenhorst, Lars, Bähr, Mathias, Fischer, André, Lingor, Paul
Published in Molecular therapy. Nucleic acids (01.06.2018)
Published in Molecular therapy. Nucleic acids (01.06.2018)
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Journal Article
Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation
Carboni, Eleonora, Tatenhorst, Lars, Tönges, Lars, Barski, Elisabeth, Dambeck, Vivian, Bähr, Mathias, Lingor, Paul
Published in Neuromolecular medicine (01.09.2017)
Published in Neuromolecular medicine (01.09.2017)
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Journal Article
PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion
Seufert, Sebastian, Coras, Roland, Tränkle, Christian, Zlotos, Darius P., Blümcke, Ingmar, Tatenhorst, Lars, Heneka, Michael T., Hahnen, Eric
Published in PPAR Research (01.01.2008)
Published in PPAR Research (01.01.2008)
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Journal Article
Deferiprone Rescues Behavioral Deficits Induced by Mild Iron Exposure in a Mouse Model of Alpha-Synuclein Aggregation
Carboni, Eleonora, Tatenhorst, Lars, Tönges, Lars, Barski, Elisabeth, Dambeck, Vivian, Bähr, Mathias, Lingor, Paul
Published in Neuromolecular medicine (01.09.2017)
Published in Neuromolecular medicine (01.09.2017)
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Journal Article
Loss of the parkinsonism‐associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects
Wang, Jingbo, Joseph, Sabitha, Vingill, Siv, Dere, Ekrem, Tatenhorst, Lars, Ronnenberg, Anja, Lingor, Paul, Preisinger, Christian, Ehrenreich, Hannelore, Schulz, Jörg B., Stegmüller, Judith
Published in Journal of neurochemistry (01.10.2023)
Published in Journal of neurochemistry (01.10.2023)
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Journal Article
Knockdown of NEAT1 prevents post-stroke lipid droplet agglomeration in microglia by regulating autophagy
Pan, Yongli, Xin, Wenqiang, Wei, Wei, Tatenhorst, Lars, Graf, Irina, Popa-Wagner, Aurel, Gerner, Stefan T., Huber, Sabine E., Kilic, Ertugrul, Hermann, Dirk M., Bähr, Mathias, Huttner, Hagen B., Doeppner, Thorsten R.
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
Published in Cellular and molecular life sciences : CMLS (01.12.2024)
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Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain
Zhang, Shuyu, Dauer, Karina, Strohäker, Timo, Tatenhorst, Lars, Caldi Gomes, Lucas, Mayer, Simon, Jung, Byung Chul, Kim, Woojin S., Lee, Seung‐Jae, Becker, Stefan, Liesche‐Starnecker, Friederike, Zweckstetter, Markus, Lingor, Paul
Published in Brain pathology (Zurich, Switzerland) (01.09.2023)
Published in Brain pathology (Zurich, Switzerland) (01.09.2023)
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Journal Article
Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils
Dauer née Joppe, Karina, Tatenhorst, Lars, Caldi Gomes, Lucas, Zhang, Shuyu, Parvaz, Mojan, Carboni, Eleonora, Roser, Anna‐Elisa, El DeBakey, Hazem, Bähr, Mathias, Vogel‐Mikuš, Katarina, Wang Ip, Chi, Becker, Stefan, Zweckstetter, Markus, Lingor, Paul
Published in Journal of neurochemistry (01.11.2021)
Published in Journal of neurochemistry (01.11.2021)
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Journal Article
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease
TÖNGES, Lars, FRANK, Tobias, TATENHORST, Lars, SAAL, Kim A, KOCH, Jan C, SZEGO, Eva M, BÄHR, Mathias, WEISHAUPT, Jochen H, LINGOR, Paul
Published in Brain (London, England : 1878) (01.11.2012)
Published in Brain (London, England : 1878) (01.11.2012)
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