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Published in Molecular and cellular endocrinology (15.05.2019)
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Impact of GPCR Structures on Drug Discovery
Congreve, Miles, de Graaf, Chris, Swain, Nigel A., Tate, Christopher G.
Published in Cell (02.04.2020)
Published in Cell (02.04.2020)
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Molecular signatures of G-protein-coupled receptors
Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Tate, Christopher G., Schertler, Gebhard F., Babu, M. Madan
Published in Nature (London) (14.02.2013)
Published in Nature (London) (14.02.2013)
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A crystal clear solution for determining G-protein-coupled receptor structures
Tate, Christopher G.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.09.2012)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.09.2012)
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Mini-G proteins: Novel tools for studying GPCRs in their active conformation
Nehmé, Rony, Carpenter, Byron, Singhal, Ankita, Strege, Annette, Edwards, Patricia C, White, Courtney F, Du, Haijuan, Grisshammer, Reinhard, Tate, Christopher G
Published in PloS one (20.04.2017)
Published in PloS one (20.04.2017)
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Structure of the adenosine A2A receptor bound to an engineered G protein
Carpenter, Byron, Nehmé, Rony, Warne, Tony, Leslie, Andrew G. W., Tate, Christopher G.
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
Lebon, Guillaume, Warne, Tony, Edwards, Patricia C., Bennett, Kirstie, Langmead, Christopher J., Leslie, Andrew G. W., Tate, Christopher G.
Published in Nature (London) (18.05.2011)
Published in Nature (London) (18.05.2011)
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Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go
García-Nafría, Javier, Nehmé, Rony, Edwards, Patricia C., Tate, Christopher G.
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
Venkatakrishnan, A. J., Deupi, Xavier, Lebon, Guillaume, Heydenreich, Franziska M., Flock, Tilman, Miljus, Tamara, Balaji, Santhanam, Bouvier, Michel, Veprintsev, Dmitry B., Tate, Christopher G., Schertler, Gebhard F. X., Babu, M. Madan
Published in Nature (London) (25.08.2016)
Published in Nature (London) (25.08.2016)
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Structure determination of GPCRs: cryo-EM compared with X-ray crystallography
García-Nafría, Javier, Tate, Christopher G
Published in Biochemical Society transactions (01.11.2021)
Published in Biochemical Society transactions (01.11.2021)
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Journal Article
Structure of the adenosine A(2A) receptor bound to an engineered G protein
Carpenter, Byron, Nehmé, Rony, Warne, Tony, Leslie, Andrew G W, Tate, Christopher G
Published in Nature (London) (04.08.2016)
Published in Nature (London) (04.08.2016)
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New insights into GPCR coupling and dimerisation from cryo-EM structures
Gusach, Anastasiia, García-Nafría, Javier, Tate, Christopher G.
Published in Current opinion in structural biology (01.06.2023)
Published in Current opinion in structural biology (01.06.2023)
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How Do Branched Detergents Stabilize GPCRs in Micelles?
Lee, Sangbae, Ghosh, Soumadwip, Jana, Suvamay, Robertson, Nathan, Tate, Christopher G, Vaidehi, Nagarajan
Published in Biochemistry (Easton) (16.06.2020)
Published in Biochemistry (Easton) (16.06.2020)
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How Can Mutations Thermostabilize G-Protein-Coupled Receptors?
Vaidehi, Nagarajan, Grisshammer, Reinhard, Tate, Christopher G
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2016)
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2016)
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Agonist-bound structures of G protein-coupled receptors
Lebon, Guillaume, Warne, Tony, Tate, Christopher G
Published in Current opinion in structural biology (01.08.2012)
Published in Current opinion in structural biology (01.08.2012)
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