Crosstalk of ROS/RNS and autophagy in silibinin- induced apoptosis of MCF-7 human breast cancer cells in vitro
Zheng, Nan, Liu, Lu, Liu, Wei-Wei, Li, Fei, Hayashi, Toshihiko, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Acta pharmacologica Sinica (01.02.2017)
Published in Acta pharmacologica Sinica (01.02.2017)
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ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells
Zheng, Nan, Zhang, Ping, Huang, Huai, Liu, Weiwei, Hayashi, Toshihiko, Zang, Linghe, Zhang, Ye, Liu, Lu, Xia, Mingyu, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of pharmacological sciences (01.07.2015)
Published in Journal of pharmacological sciences (01.07.2015)
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Journal Article
Inhibition of c-Met promoted apoptosis, autophagy and loss of the mitochondrial transmembrane potential in oridonin-induced A549 lung cancer cells
Liu, Ying, Liu, Jian-Hong, Chai, Kuan, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of pharmacy and pharmacology (01.11.2013)
Published in Journal of pharmacy and pharmacology (01.11.2013)
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Journal Article
Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ 1-42 -induced reactive oxygen species/reactive nitrogen species generation
Yang, Jing, Sun, Yue, Xu, Fanxing, Liu, Weiwei, Hayashi, Toshihiko, Hattori, Shunji, Ushiki-Kaku, Yuko, Onodera, Satoshi, Tashiro, Shin-Ichi, Ikejima, Takashi
Published in Phytotherapy research (01.04.2019)
Published in Phytotherapy research (01.04.2019)
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Journal Article
Autophagy Preceded Apoptosis in Oridonin-Treated Human Breast Cancer MCF-7 Cells
Cui, Qiao, Tashiro, Shin-ichi, Onodera, Satoshi, Minami, Mutsuhiko, Ikejima, Takashi
Published in Biological & Pharmaceutical Bulletin (01.05.2007)
Published in Biological & Pharmaceutical Bulletin (01.05.2007)
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Type I collagen-induced YAP nuclear expression promotes primary cilia growth and contributes to cell migration in confluent mouse embryo fibroblast 3T3-L1 cells
Xu, Qian, Liu, Xiaoling, Liu, Weiwei, Hayashi, Toshihiko, Yamato, Masayuki, Fujisaki, Hitomi, Hattori, Shunji, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Molecular and cellular biochemistry (01.01.2019)
Published in Molecular and cellular biochemistry (01.01.2019)
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Journal Article
Estrogen Receptors Are Involved in the Neuroprotective Effect of Silibinin in Aβ1–42-Treated Rats
Song, Xiaoyu, Liu, Bo, Cui, Lingyu, Zhou, Biao, Liu, Lu, Liu, Weiwei, Yao, Guodong, Xia, Mingyu, Hayashi, Toshihiko, Hattori, Shunji, Ushiki-Kaku, Yuko, Tashiro, Shin-ichi, Ikejima, Takashi
Published in Neurochemical research (01.04.2018)
Published in Neurochemical research (01.04.2018)
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Journal Article
RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy
Ye, Yuan-Chao, Wang, Hong-Ju, Yu, Lu, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in International immunopharmacology (01.12.2012)
Published in International immunopharmacology (01.12.2012)
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Autophagy inhibits reactive oxygen species‐mediated apoptosis via activating p38‐nuclear factor‐kappa B survival pathways in oridonin‐treated murine fibrosarcoma L929 cells
Cheng, Yan, Qiu, Feng, Ye, Yuan‐Chao, Guo, Zhao‐Ming, Tashiro, Shin‐Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in The FEBS journal (01.03.2009)
Published in The FEBS journal (01.03.2009)
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Journal Article
Activation of ERK–p53 and ERK-Mediated Phosphorylation of Bcl-2 Are Involved in Autophagic Cell Death Induced by the c-Met Inhibitor SU11274 in Human Lung Cancer A549 Cells
Liu, Ying, Yang, Ying, Ye, Yuan-Chao, Shi, Qi-Feng, Chai, Kuan, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Journal of Pharmacological Sciences (2012)
Published in Journal of Pharmacological Sciences (2012)
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Journal Article
Silibinin protects murine fibroblast L929 cells from UVB‐induced apoptosis through the simultaneous inhibition of ATM‐p53 pathway and autophagy
Liu, Weiwei, Otkur, Wuxiyar, Zhang, Yuning, Li, Qiuyuan, Ye, Yuanchao, Zang, Linghe, He, Hao, Hayashi, Toshihiko, Tashiro, Shin‐ichi, Onodera, Satoshi, Ikejima, Takashi
Published in The FEBS journal (01.09.2013)
Published in The FEBS journal (01.09.2013)
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Journal Article
Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells
Cheng, Yan, Qiu, Feng, Ye, Yuan-chao, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Archives of biochemistry and biophysics (01.10.2009)
Published in Archives of biochemistry and biophysics (01.10.2009)
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Journal Article
Timosaponin AIII induces apoptosis and autophagy in human melanoma A375-S2 cells
Wang, Ye, Xu, Lei, Lou, Li-Li, Song, Shao-Jiang, Yao, Guo-Dong, Ge, Meng-Yao, Hayashi, Toshihiko, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Archives of pharmacal research (2017)
Published in Archives of pharmacal research (2017)
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Journal Article
Silibinin protects rat pancreatic β‐cell through up‐regulation of estrogen receptors' signaling against amylin‐ or Aβ1–42‐induced reactive oxygen species/reactive nitrogen species generation
Yang, Jing, Sun, Yue, Xu, Fanxing, Liu, Weiwei, Hayashi, Toshihiko, Hattori, Shunji, Ushiki‐Kaku, Yuko, Onodera, Satoshi, Tashiro, Shin‐ichi, Ikejima, Takashi
Published in Phytotherapy research (01.04.2019)
Published in Phytotherapy research (01.04.2019)
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Journal Article
Gelatin promotes cell aggregation and pro-inflammatory cytokine production in PMA-stimulated U937 cells by augmenting endocytosis-autophagy pathway
Zhao, Ye-Li, Lu, Zhuo-Yu, Zhang, Xuan, Liu, Wei-Wei, Yao, Guo-Dong, Liu, Xiao-Ling, Liu, Wei, Wu, Qing-Jie, Hayashi, Toshihiko, Yamato, Masayuki, Fujisaki, Hitomi, Hattori, Shunji, Atsuzawa, Yuji, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in The international journal of biochemistry & cell biology (01.02.2018)
Published in The international journal of biochemistry & cell biology (01.02.2018)
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Journal Article
Activated toll-like receptor 4 is involved in oridonin-induced phagocytosis via promotion of migration and autophagy-lysosome pathway in RAW264.7 macrophages
Zang, Linghe, Wang, Jian, Ren, Yanlin, Liu, Weiwei, Yu, Yang, Zhao, Songyan, Otkur, Wuxiyar, Zhao, Yingxi, Hayashi, Toshihiko, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Published in International immunopharmacology (01.01.2019)
Published in International immunopharmacology (01.01.2019)
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Journal Article
Type I collagen promotes primary cilia growth through down-regulating HDAC6-mediated autophagy in confluent mouse embryo fibroblast 3T3-L1 cells
Xu, Qian, Liu, Weiwei, Liu, Xiaoling, Otkur, Wuxiyar, Hayashi, Toshihiko, Yamato, Masayuki, Fujisaki, Hitomi, Hattori, Shunji, Tashiro, Shin-ichi, Ikejima, Takashi
Published in Journal of bioscience and bioengineering (01.01.2018)
Published in Journal of bioscience and bioengineering (01.01.2018)
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Journal Article
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK
Fan, Simiao, Qi, Min, Yu, Yang, Li, Lihua, Yao, Guodong, Tashiro, Shin-Ichi, Onodera, Satoshi, Ikejima, Takashi
Published in Free radical research (01.03.2012)
Published in Free radical research (01.03.2012)
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