An Improved, Practical, and Scalable Five-Step Synthesis of Psilocybin
Sherwood, Alexander M., Meisenheimer, Poncho, Tarpley, Gary, Kargbo, Robert B.
Published in Synthesis (Stuttgart) (03.03.2020)
Published in Synthesis (Stuttgart) (03.03.2020)
Get more information
Journal Article
Direct Phosphorylation of Psilocin Enables Optimized cGMP Kilogram-Scale Manufacture of Psilocybin
Kargbo, Robert B, Sherwood, Alexander, Walker, Andrew, Cozzi, Nicholas V, Dagger, Raymond E, Sable, Jessica, O’Hern, Kelsey, Kaylo, Kristi, Patterson, Tura, Tarpley, Gary, Meisenheimer, Poncho
Published in ACS omega (14.07.2020)
Published in ACS omega (14.07.2020)
Get full text
Journal Article
Tipranavir inhibits broadly protease inhibitor-resistant HIV-1 clinical samples
LARDER, Brendan A, HERTOGS, Kurt, BLOOR, Stuart, VAN DEN EYNDE, Ch, DECIAN, Wanda, YENYUN WANG, FREIMUTH, William W, TARPLEY, Gary
Published in AIDS (London) (08.09.2000)
Published in AIDS (London) (08.09.2000)
Get full text
Journal Article
Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial
Raison, Charles L, Sanacora, Gerard, Woolley, Joshua, Heinzerling, Keith, Dunlop, Boadie W, Brown, Randall T, Kakar, Rishi, Hassman, Michael, Trivedi, Rupal P, Robison, Reid, Gukasyan, Natalie, Nayak, Sandeep M, Hu, Xiaojue, O’Donnell, Kelley C, Kelmendi, Benjamin, Sloshower, Jordan, Penn, Andrew D, Bradley, Ellen, Kelly, Daniel F, Mletzko, Tanja, Nicholas, Christopher R, Hutson, Paul R, Tarpley, Gary, Utzinger, Malynn, Lenoch, Kelsey, Warchol, Kasia, Gapasin, Theraysa, Davis, Mike C, Nelson-Douthit, Courtney, Wilson, Steffanie, Brown, Carrie, Linton, William, Ross, Stephen, Griffiths, Roland R
Published in JAMA : the journal of the American Medical Association (05.09.2023)
Published in JAMA : the journal of the American Medical Association (05.09.2023)
Get full text
Journal Article
Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors
Thaisrivongs, Suvit, Skulnick, Harvey I, Turner, Steve R, Strohbach, Joseph W, Tommasi, Ruben A, Johnson, Paul D, Aristoff, Paul A, Judge, Thomas M, Gammill, Ronald B, Morris, Jeanette K, Romines, Karen R, Chrusciel, Robert A, Hinshaw, Roger R, Chong, Kong-Teck, Tarpley, W. Gary, Poppe, Susan M, Slade, David E, Lynn, Janet C, Horng, Miao-Miao, Tomich, Paul K, Seest, Eric P, Dolak, Lester A, Howe, W. Jeffrey, Howard, Gina M, Schwende, Francis J, Toth, Lisa N, Padbury, Guy E, Wilson, Grace J, Shiou, Lihua, Zipp, Gail L, Wilkinson, Karen F, Rush, Bob D, Ruwart, Mary J, Koeplinger, Kenneth A, Zhao, Zhiyang, Cole, Serena, Zaya, Renee M, Kakuk, Thomas J, Janakiraman, Musiri N, Watenpaugh, Keith D
Published in Journal of medicinal chemistry (25.10.1996)
Published in Journal of medicinal chemistry (25.10.1996)
Get full text
Journal Article
Association of Integrase, Matrix, and Reverse Transcriptase Antigens of Human Immunodeficiency Virus Type 1 with Viral Nucleic Acids Following Acute Infection
Bukrinsky, Michael I., Sharova, Natalia, McDonald, Thomas L., Pushkarskaya, Tatyana, Tarpley, W. Gary, Stevenson, Mario
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1993)
Get full text
Journal Article
A Drug Resistance Mutation in the Inhibitor Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Impairs DNA Synthesis and RNA Degradation
Fan, Naisheng, Rank, Kenneth B, Slade, David E, Poppe, Susan M, Evans, David B, Kopta, Laurice A, Olmsted, Robert A, Thomas, Richard C, Tarpley, W. Gary, Sharma, Satish K
Published in Biochemistry (Easton) (30.07.1996)
Published in Biochemistry (Easton) (30.07.1996)
Get full text
Journal Article
A Mutation in Reverse Transcriptase of Bis(heteroaryl)Piperazine-Resistant Human Immunodeficiency Virus Type 1 that Confers Increased Sensitivity to Other Nonnucleoside Inhibitors
Dueweke, Thomas J., Pushkarskaya, Tatyana, Poppe, Susan M., Swaney, Steven M., Zhao, Jia Q., Irvin S. Y. Chen, Stevenson, Mario, Tarpley, W. Gary
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.1993)
Get full text
Journal Article
A recombinant ribonuclease H domain of HIV-1 reverse transcriptase that is enzymatically active
Evans, D.B., Brawn, K., Deibel, M.R., Tarpley, W.G., Sharma, S.K.
Published in The Journal of biological chemistry (05.11.1991)
Published in The Journal of biological chemistry (05.11.1991)
Get full text
Journal Article
(−)-6-Chloro-2-[(1-furo[2,3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor
Wishka, Donn G, Graber, David R, Kopta, Laurice A, Olmsted, Robert A, Friis, Janice M, Hosley, John D, Adams, Wade J, Seest, Eric P, Castle, Thomas M, Dolak, Lester A, Keiser, Barbara J, Yagi, Yoshihiko, Jeganathan, Azhwarsamy, Schlachter, Stephen T, Murphy, Michael J, Cleek, Gary J, Nugent, Richard A, Poppe, Susan M, Swaney, Steven M, Han, Fusen, Watt, William, White, Wendy L, Poel, Toni-Jo, Thomas, Richard C, Voorman, Richard L, Stefanski, Kevin J, Stehle, Randall G, Tarpley, W. Gary, Morris, Joel
Published in Journal of medicinal chemistry (23.04.1998)
Published in Journal of medicinal chemistry (23.04.1998)
Get full text
Journal Article
Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives
Genin, Michael J, Biles, Carolyn, Keiser, Barb J, Poppe, Susan M, Swaney, Steven M, Tarpley, W. Gary, Yagi, Yoshihiko, Romero, Donna L
Published in Journal of medicinal chemistry (09.03.2000)
Published in Journal of medicinal chemistry (09.03.2000)
Get full text
Journal Article
(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes
Olmsted, R A, Slade, D E, Kopta, L A, Poppe, S M, Poel, T J, Newport, S W, Rank, K B, Biles, C, Morge, R A, Dueweke, T J, Yagi, Y, Romero, D L, Thomas, R C, Sharma, S K, Tarpley, W G
Published in Journal of Virology (01.06.1996)
Published in Journal of Virology (01.06.1996)
Get full text
Journal Article
Oxazolidinones: a new class of antibacterials
Zurenko, Gary E, Gibson, John K, Shinabarger, Dean L, Aristoff, Paul A, Ford, Charles W, Tarpley, W.Gary
Published in Current Opinion in Pharmacology (01.10.2001)
Published in Current Opinion in Pharmacology (01.10.2001)
Get full text
Book Review
Journal Article
Simultaneous mutations at Tyr-181 and Tyr-188 in HIV-1 reverse transcriptase prevents inhibition of RNA-dependent DNA polymerase activity by the bisheteroarylpiperazine (BHAP) U-90152s
Fan, Naisheng, Rank, Kenneth B., Evans, David B., Thomas, Richard C., Gary Tarpley, W., Sharma, Satish K.
Published in FEBS letters (14.08.1995)
Published in FEBS letters (14.08.1995)
Get full text
Journal Article
The lack of PDGF-stimulated PGE 2 release from [formula omitted]-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A 2 activity
Benjamin, C.W., Gary Tarpley, W., Gorman, Robert R.
Published in Biochemical and biophysical research communications (1987)
Published in Biochemical and biophysical research communications (1987)
Get full text
Journal Article
Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E
Althaus, I W, Chou, J J, Gonzales, A J, Deibel, M R, Chou, K C, Kezdy, F J, Romero, D L, Aristoff, P A, Tarpley, W G, Reusser, F
Published in The Journal of biological chemistry (25.03.1993)
Published in The Journal of biological chemistry (25.03.1993)
Get full text
Journal Article
Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E
Althaus, Irene W, Chou, James J, Gonzales, Andrea J, Deibel, Martin R, Chou, Kuo Chen, Kezdy, Ferenc J, Romero, Donna L, Palmer, John R, Thomas, Richard C
Published in Biochemistry (Easton) (01.07.1993)
Published in Biochemistry (Easton) (01.07.1993)
Get full text
Journal Article
The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase
ALTHAUS, I. W, GONZALES, A. J, DOWNEY, K. M, THOMAS, R. C, ARISTOFF, P. A, TARPLEY, W. G, REUSSER, F, CHOU, J. J, ROMERO, D. L, DEIBEL, M. R, KUO-CHEN CHOU, KEZDY, F. J, RESNICK, L, BUSSO, M. E, SO, A. G
Published in The Journal of biological chemistry (15.07.1993)
Published in The Journal of biological chemistry (15.07.1993)
Get full text
Journal Article
An Inhibitor of the Protease Blocks Maturation of Human and Simian Immunodeficiency Viruses and Spread of Infection
Ashorn, Per, McQuade, Thomas J., Thaisrivongs, Suvit, Tomasselli, Alfredo G., Tarpley, W. Gary, Moss, Bernard
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.1990)
Get full text
Journal Article