Gene-microbiota interactions contribute to the pathogenesis of inflammatory bowel disease
Chu, Hiutung, Khosravi, Arya, Kusumawardhani, Indah P., Kwon, Alice H. K., Vasconcelos, Anilton C., Cunha, Larissa D., Mayer, Anne E., Shen, Yue, Wu, Wei-Li, Kambal, Amal, Targan, Stephan R., Xavier, Ramnik J., Ernst, Peter B., Green, Douglas R., McGovern, Dermot P. B., Virgin, Herbert W., Mazmanian, Sarkis K.
Published in Science (American Association for the Advancement of Science) (27.05.2016)
Published in Science (American Association for the Advancement of Science) (27.05.2016)
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Microbiota activation and regulation of innate and adaptive immunity
Alexander, Katie L., Targan, Stephan R., Elson III, Charles O.
Published in Immunological reviews (01.07.2014)
Published in Immunological reviews (01.07.2014)
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Andrographis paniculata extract (HMPL-004) for active ulcerative colitis
Sandborn, William J, Targan, Stephan R, Byers, Vera S, Rutty, Dean A, Mu, Hua, Zhang, Xun, Tang, Tom
Published in The American journal of gastroenterology (01.01.2013)
Published in The American journal of gastroenterology (01.01.2013)
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Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis
Shih, David Q, Barrett, Robert, Zhang, Xiaolan, Yeager, Nicole, Koon, Hon Wai, Phaosawasdi, Piangwarin, Song, Yahui, Ko, Brian, Wong, Michelle H, Michelsen, Kathrin S, Martins, Gislaine, Pothoulakis, Charalabos, Targan, Stephan R
Published in PloS one (11.01.2011)
Published in PloS one (11.01.2011)
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Enhanced Utilization of Induced Pluripotent Stem Cell–Derived Human Intestinal Organoids Using Microengineered Chips
Workman, Michael J, Gleeson, John P, Troisi, Elissa J, Estrada, Hannah Q, Kerns, S. Jordan, Hinojosa, Christopher D, Hamilton, Geraldine A, Targan, Stephan R, Svendsen, Clive N, Barrett, Robert J
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
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Modeling Intestinal Epithelial Response to Interferon-γ in Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids
Workman, Michael J, Troisi, Elissa, Targan, Stephan R, Svendsen, Clive N, Barrett, Robert J
Published in International journal of molecular sciences (30.12.2020)
Published in International journal of molecular sciences (30.12.2020)
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Journal Article
Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial
Targan, Stephan R, Feagan, Brian G, Fedorak, Richard N, Lashner, Bret A, Panaccione, Remo, Present, Daniel H, Spehlmann, Martina E, Rutgeerts, Paul J, Tulassay, Zsolt, Volfova, Miroslava, Wolf, Douglas C, Hernandez, Chito, Bornstein, Jeffrey, Sandborn, William J
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2007)
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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
Cho, Judy H, Taylor, Kent D, Daly, Mark J, Silverberg, Mark S, Nicolae, Dan L, Goyette, Philippe, Steinhart, A Hillary, Rotter, Jerome I, Schumm, L Philip, Duerr, Richard H, Shugart, Yin Yao, Griffiths, Anne M, Huett, Alan, Ippoliti, Andrew F, Bernard, Edmond-Jean, Kuballa, Petric, Xavier, Ramnik J, Barmada, M Michael, Rioux, John D, Datta, Lisa Wu, Green, Todd, Regueiro, Miguel, Targan, Stephan R, Brant, Steven R, Mei, Ling
Published in Nature genetics (01.05.2007)
Published in Nature genetics (01.05.2007)
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Development of Physiologically Responsive Human iPSC-Derived Intestinal Epithelium to Study Barrier Dysfunction in IBD
Gleeson, John P, Estrada, Hannah Q, Yamashita, Michifumi, Svendsen, Clive N, Targan, Stephan R, Barrett, Robert J
Published in International journal of molecular sciences (20.02.2020)
Published in International journal of molecular sciences (20.02.2020)
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Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis
Zhang, Hong, Zheng, Libo, McGovern, Dermot P B, Hamill, Ariel M, Ichikawa, Ryan, Kanazawa, Yoshitake, Luu, Justin, Kumagai, Kotaro, Cilluffo, Marianne, Fukata, Masayuki, Targan, Stephan R, Underhill, David M, Zhang, Xiaolan, Shih, David Q
Published in The Journal of immunology (1950) (01.03.2017)
Published in The Journal of immunology (1950) (01.03.2017)
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Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis
Wenxiu, Jia, Mingyue, Yang, Fei, Han, Yuxin, Luo, Mengyao, Wu, Chenyang, Li, Jia, Song, Hong, Zhang, Shih, David Q., Targan, Stephan R., Xiaolan, Zhang
Published in Mediators of inflammation (25.06.2021)
Published in Mediators of inflammation (25.06.2021)
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Journal Article
Abatacept for Crohn's Disease and Ulcerative Colitis
Sandborn, William J, Colombel, Jean–Frederic, Sands, Bruce E, Rutgeerts, Paul, Targan, Stephan R, Panaccione, Remo, Bressler, Brian, Geboes, Karl, Schreiber, Stefan, Aranda, Richard, Gujrathi, Sheila, Luo, Allison, Peng, Yun, Salter–Cid, Luisa, Hanauer, Stephen B
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2012)
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Diagnostic and therapeutic potential of RNASET2 in Crohn's disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombinant-RNASET2 attenuates pro-inflammatory cytokine secretion
Biener-Ramanujan, Eva, Rosier, Florian, Coetzee, Simon G, McGovern, Dermot D P, Hazelett, Dennis, Targan, Stephan R, Gonsky, Rivkah
Published in Frontiers in immunology (16.11.2022)
Published in Frontiers in immunology (16.11.2022)
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Toll-like receptor 7 protects against intestinal inflammation and restricts the development of colonic tissue-resident memory CD8 + T cells
Hamade, Hussein, Tsuda, Masato, Oshima, Naoki, Stamps, Dalton T, Wong, Michelle H, Stamps, Jasmine T, Thomas, Lisa S, Salumbides, Brenda C, Jin, Caroline, Nunnelee, Jordan S, Dhall, Deepti, Targan, Stephan R, Michelsen, Kathrin S
Published in Frontiers in immunology (11.10.2024)
Published in Frontiers in immunology (11.10.2024)
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Journal Article
Bacterial flagellin is a dominant antigen in Crohn disease
Lodes, Michael J, Cong, Yingzi, Elson, Charles O, Mohamath, Raodoh, Landers, Carol J, Targan, Stephan R, Fort, Madeline, Hershberg, Robert M
Published in The Journal of clinical investigation (01.05.2004)
Published in The Journal of clinical investigation (01.05.2004)
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Future biologic targets for IBD: potentials and pitfalls
Melmed, Gil Y, Targan, Stephan R
Published in Nature reviews. Gastroenterology & hepatology (01.02.2010)
Published in Nature reviews. Gastroenterology & hepatology (01.02.2010)
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Journal Article
Biologic therapy of inflammatory bowel disease
Sandborn, William J, Targan, Stephan R
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2002)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2002)
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