A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency
Lagresle-Peyrou, Chantal, Olichon, Aurélien, Sadek, Hanem, Roche, Philippe, Tardy, Claudine, Da Silva, Cindy, Garrigue, Alexandrine, Fischer, Alain, Moshous, Despina, Collette, Yves, Picard, Capucine, Casanova, Jean Laurent, André, Isabelle, Cavazzana, Marina
Published in Haematologica (Roma) (01.02.2021)
Published in Haematologica (Roma) (01.02.2021)
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Journal Article
CER-001, a HDL-mimetic, stimulates the reverse lipid transport and atherosclerosis regression in high cholesterol diet-fed LDL-receptor deficient mice
Tardy, Claudine, Goffinet, Marine, Boubekeur, Nadia, Ackermann, Rose, Sy, Gavin, Bluteau, Alice, Cholez, Guy, Keyserling, Constance, Lalwani, Narendra, Paolini, John F, Dasseux, Jean-Louis, Barbaras, Ronald, Baron, Rudi
Published in Atherosclerosis (01.01.2014)
Published in Atherosclerosis (01.01.2014)
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Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies
Figarol, Sarah, Delahaye, Célia, Gence, Rémi, Doussine, Aurélia, Cerapio, Juan Pablo, Brachais, Mathylda, Tardy, Claudine, Béry, Nicolas, Asslan, Raghda, Colinge, Jacques, Villemin, Jean-Philippe, Maraver, Antonio, Ferrer, Irene, Paz-Ares, Luis, Kessler, Linda, Burrows, Francis, Lajoie-Mazenc, Isabelle, Dongay, Vincent, Morin, Clara, Florent, Amélie, Pagano, Sandra, Taranchon-Clermont, Estelle, Casanova, Anne, Pradines, Anne, Mazieres, Julien, Favre, Gilles, Calvayrac, Olivier
Published in Nature communications (27.06.2024)
Published in Nature communications (27.06.2024)
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Tripartite split-GFP assay to identify selective intracellular nanobody that suppresses GTPase RHOA subfamily downstream signaling
Keller, Laura, Tardy, Claudine, Ligat, Laetitia, Le Pennec, Soazig, Bery, Nicolas, Koraïchi, Faten, Chinestra, Patrick, David, Mélissa, Gence, Rémi, Favre, Gilles, Cabantous, Stéphanie, Olichon, Aurélien
Published in Frontiers in immunology (18.08.2022)
Published in Frontiers in immunology (18.08.2022)
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Journal Article
HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE-/- Mice: Evidence of ABCA1 Down-Regulation
Tardy, Claudine, Goffinet, Marine, Boubekeur, Nadia, Cholez, Guy, Ackermann, Rose, Sy, Gavin, Keyserling, Constance, Lalwani, Narendra, Paolini, John F, Dasseux, Jean-Louis, Barbaras, Ronald, Baron, Rudi
Published in PloS one (03.09.2015)
Published in PloS one (03.09.2015)
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Journal Article
Selection and Characterization of a Nanobody Biosensor of GTP-Bound RHO Activities
Keller, Laura, Bery, Nicolas, Tardy, Claudine, Ligat, Laetitia, Favre, Gilles, Rabbitts, Terence H, Olichon, Aurélien
Published in Antibodies (Basel) (09.01.2019)
Published in Antibodies (Basel) (09.01.2019)
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Journal Article
P2Y13 receptor regulates HDL metabolism and atherosclerosis in vivo
Goffinet, Marine, Tardy, Claudine, Boubekeur, Nadia, Cholez, Guy, Bluteau, Alice, Oniciu, Daniela C, Lalwani, Narendra D, Dasseux, Jean-Louis H, Barbaras, Ronald, Baron, Rudi
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Journal Article
Cdk1 is sufficient to drive the mammalian cell cycle
Hunt, Sarah, Tardy, Claudine, Cáceres, Javier F, Dubus, Pierre, Newton, Kathryn, Malumbres, Marcos, Barbacid, Mariano, Barrière, Cédric, Santamaría, David, Cerqueira, Antonio
Published in Nature (London) (16.08.2007)
Published in Nature (London) (16.08.2007)
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Journal Article
Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer
Keller, Laura, Tardy, Claudine, Ligat, Laetitia, Gilhodes, Julia, Filleron, Thomas, Bery, Nicolas, Rochaix, Philippe, Aquilina, Alexis, Bdioui, Sara, Roux, Thomas, Trinquet, Eric, Favre, Gilles, Olichon, Aurélien
Published in Analytical chemistry (Washington) (20.04.2021)
Published in Analytical chemistry (Washington) (20.04.2021)
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Journal Article
An Autosomal Dominant Form of Ras-Related C3 Botulinum Toxin Substrate 2 (RAC2) Is Associated with Haematopoiesis Failure
Lagresle-Peyrou, Chantal, Olichon, Aurélien, Sadek, Hanem, Roche, Philippe, Tardy, Claudine, Sorel, Natael, Bessot, Boris, Da Silva, Cindy, Fischer, Alain, Moshous, Despina, Collette, Yves, Picard, Capucine, Casanova, Jean-Laurent, André, Isabelle, Cavazzana, Marina
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
An Autosomal Dominant SCID Form Due to a Gain of Function Mutation in the RAC2 Gene
Lagresle-Peyrou, Chantal, Olichon, Aurélien, Sadek, Hanem, Roche, Philippe, Tardy, Claudine, Da Silva, Cindy, Garrigue, Alexandrine, Fischer, Alain, Moshous, Despina, Collette, Yves, Picard, Capucine, Casanova, Jean-Laurent, André, Isabelle, Cavazzana, Marina
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
HDL and CER-001 Inverse-Dose Dependent Inhibition of Atherosclerotic Plaque Formation in apoE.sup.-/- Mice: Evidence of ABCA1 Down-Regulation
Tardy, Claudine, Goffinet, Marine, Boubekeur, Nadia, Cholez, Guy, Ackermann, Rose, Sy, Gavin, Keyserling, Constance, Lalwani, Narendra, Paolini, John F, Dasseux, Jean-Louis, Barbaras, Ronald, Baron, Rudi
Published in PloS one (03.09.2015)
Published in PloS one (03.09.2015)
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Journal Article
Palmitoyl protein thioesterase 1 modulates tumor necrosis factor α-induced apoptosis
Tardy, Claudine, Sabourdy, Frédérique, Garcia, Virginie, Jalanko, Anu, Therville, Nicole, Levade, Thierry, Andrieu-Abadie, Nathalie
Published in Biochimica et biophysica acta (01.07.2009)
Published in Biochimica et biophysica acta (01.07.2009)
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Journal Article
Abstract 18667: Anti-atherosclerotic Effect of CER-001, an Engineered HDL-mimetic, in the High-fat Diet-fed LDLr Knockout Mice
Goffinet, Marine, Tardy, Claudine, Bluteau, Alice, Boubekeur, Nadia, Baron, Rudi, Keyserling, Constance, Barbaras, Ronald, Lalwani, Narendra, Dasseux, Jean-Louis
Published in Circulation (New York, N.Y.) (20.11.2012)
Published in Circulation (New York, N.Y.) (20.11.2012)
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Journal Article
Abstract 493: Antiatherosclerotic Activity of a New P2y13 Receptor Agonist (ct1007900) in Animal Models
Barbaras, Ronald, Baron, Rudi, Goffinet, Marine, Tardy, Claudine, Boubekeur, Nadia, Cholez, Guy, Oniciu, Daniela C, Lalwani, Narendra D, Dasseux, Jean-Louis H
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2012)
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Journal Article
Abstract 1396: FGFR1-induced radioresistance of Panc02 pancreatic tumor cells is decreased by SSR128129 treatment in vitro and in vivo
Tardy, Claudine, Gueguen, Genevieve, Mazoyer, Sandrine, Morin, Gaëlle, Planel, Severine, Herbert, Corentin, Toulas, Christine, Moyal, Elisabeth Cohen-Jonathan, Schaeffer, Paul, Bono, Françoise
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Mannose 6-phosphorylated proteins are required for tumor necrosis factor-induced apoptosis: defective response in I-cell disease fibroblasts
Tardy, Claudine, Autefage, Hélène, Garcia, Virgine, Levade, Thierry, Andrieu-Abadie, Nathalie
Published in The Journal of biological chemistry (17.12.2004)
Published in The Journal of biological chemistry (17.12.2004)
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