Elezanumab, a clinical stage human monoclonal antibody that selectively targets repulsive guidance molecule A to promote neuroregeneration and neuroprotection in neuronal injury and demyelination models
Huang, Lili, Fung, Emma, Bose, Sahana, Popp, Andreas, Böser, Preethne, Memmott, John, Kutskova, Yuliya A., Miller, Renee, Tarcsa, Edit, Klein, Corinna, Veldman, Geertruida M., Mueller, Bernhard K., Cui, Yi-Fang
Published in Neurobiology of disease (01.11.2021)
Published in Neurobiology of disease (01.11.2021)
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Journal Article
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
Wu, Chengbin, Ying, Hua, Grinnell, Christine, Bryant, Shaughn, Miller, Renee, Clabbers, Anca, Bose, Sahana, McCarthy, Donna, Zhu, Rong-Rong, Santora, Ling, Davis-Taber, Rachel, Kunes, Yune, Fung, Emma, Schwartz, Annette, Sakorafas, Paul, Gu, Jijie, Tarcsa, Edit, Murtaza, Anwar, Ghayur, Tariq
Published in Nature biotechnology (01.11.2007)
Published in Nature biotechnology (01.11.2007)
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Journal Article
Off-target binding of an anti-amyloid beta monoclonal antibody to platelet factor 4 causes acute and chronic toxicity in cynomolgus monkeys
Loberg, Lise I, Chhaya, Meha, Ibraghimov, Alexander, Tarcsa, Edit, Striebinger, Andreas, Popp, Andreas, Huang, Lili, Oellien, Frank, Barghorn, Stefan
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Analysis of chloroquine and metabolites directly from whole-body animal tissue sections by liquid extraction surface analysis (LESA) and tandem mass spectrometry
Parson, Whitney B., Koeniger, Stormy L., Johnson, Robert W., Erickson, Jamie, Tian, Yu, Stedman, Christopher, Schwartz, Annette, Tarcsa, Edit, Cole, Roderic, Van Berkel, Gary J.
Published in Journal of mass spectrometry. (01.11.2012)
Published in Journal of mass spectrometry. (01.11.2012)
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Journal Article
Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig
Bardwell, Philip D., Staron, Matthew M., Liu, Junjian, Tao, Qingfeng, Scesney, Susanne, Bukofzer, Gail, Rodriguez, Luis E., Choi, Chee-Ho, Wang, Jennifer, Chang, Qing, Dong, Feng, Donawho, Cherrie, Wang, Jieyi, Grinnell, Christine M., Tarcsa, Edit, Hutchins, Charles, Ghayur, Tariq, Gu, Jijie
Published in Protein & cell (01.01.2018)
Published in Protein & cell (01.01.2018)
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Journal Article
Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper
Yang, Tong-yuan, Braun, Manuela, Lembke, Wibke, McBlane, Fraser, Kamerud, John, DeWall, Stephen, Tarcsa, Edit, Fang, Xiaodong, Hofer, Lena, Kavita, Uma, Upreti, Vijay V., Gupta, Swati, Loo, LiNa, Johnson, Alison J., Chandode, Rakesh Kantilal, Stubenrauch, Kay-Gunnar, Vinzing, Maya, Xia, Cindy Q., Jawa, Vibha
Published in Molecular therapy. Methods & clinical development (08.09.2022)
Published in Molecular therapy. Methods & clinical development (08.09.2022)
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Journal Article
A high throughput capillary electrophoresis method to obtain pharmacokinetics and quality attributes of a therapeutic molecule in circulation
Piparia, Reema, Ouellette, David, Stine, W. Blaine, Grinnell, Christine, Tarcsa, Edit, Radziejewski, Czeslaw, Correia, Ivan
Published in mAbs (01.07.2012)
Published in mAbs (01.07.2012)
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Journal Article
Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein (∗)
Candi, Eleonora, Melino, Gerry, Mei, Giampiero, Tarcsa, Edit, Chung, Soo-Il, Marekov, Lyuben N., Steinert, Peter M.
Published in The Journal of biological chemistry (03.11.1995)
Published in The Journal of biological chemistry (03.11.1995)
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Journal Article
A Highly Conserved Lysine Residue on the Head Domain of Type II Keratins is Essential for the Attachment of Keratin Intermediate Filaments to the Cornified cell Envelope through Isopeptide Crosslinking by Transglutaminases
Candi, Eleonora, Tarcsa, Edit, Digiovanna, John J., Compton, John G., Elias, Peter M., Marekov, Lyuben N., Steinert, Peter M.
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.1998)
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Journal Article
Structural and Transglutaminase Substrate Properties of the Small Proline-rich 2 Family of Cornified Cell Envelope Proteins
Tarcsa, Edit, Candi, Eleonora, Kartasova, Tonja, Idler, William W., Marekov, Lyuben N., Steinert, Peter M.
Published in The Journal of biological chemistry (04.09.1998)
Published in The Journal of biological chemistry (04.09.1998)
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Journal Article
An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR-T and TCR-T Cellular Therapies Development
Gokemeijer, Jochem, Balasubramanian, Nanda, Ogasawara, Ken, Grudzinska-Goebel, Joanna, Upreti, Vijay V, Mody, Hardik, Kasar, Siddha, Vepachedu, Venkata R, Xu, Weifeng, Gupta, Swati, Tarcsa, Edit, Dodge, Robert, Herr, Kate, Yang, Tong-Yuan, Tourdot, Sophie, Jawa, Vibha
Published in Clinical pharmacology and therapeutics (01.02.2024)
Published in Clinical pharmacology and therapeutics (01.02.2024)
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Journal Article
Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination
Tarcsa, Edit, Szymanska, Grazyna, Lecker, Stewart, O'Connor, Clare M., Goldberg, Alfred L.
Published in The Journal of biological chemistry (07.07.2000)
Published in The Journal of biological chemistry (07.07.2000)
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Journal Article
The unfolding of substrates and ubiquitin-independentprotein degradation by proteasomes
Benaroudj, Nadia, Tarcsa, Edit, Cascio, Paolo, Goldberg, Alfred L.
Published in Biochimie (01.03.2001)
Published in Biochimie (01.03.2001)
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Journal Article
Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
Kraynov, Eugenia, Kamath, Amrita V, Walles, Markus, Tarcsa, Edit, Deslandes, Antoine, Iyer, Ramaswamy A, Datta-Mannan, Amita, Sriraman, Priya, Bairlein, Michaela, Yang, Johnny J, Barfield, Matthew, Xiao, Guangqing, Escandon, Enrique, Wang, Weirong, Rock, Dan A, Chemuturi, Nagendra V, Moore, David J
Published in Drug metabolism and disposition (01.05.2016)
Published in Drug metabolism and disposition (01.05.2016)
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