Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial
Tarcha, Eric J, Olsen, Chelsea M, Probst, Peter, Peckham, David, Muñoz-Elías, Ernesto J, Kruger, James G, Iadonato, Shawn P
Published in PloS one (19.07.2017)
Published in PloS one (19.07.2017)
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Journal Article
Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases
Chi, Victor, Pennington, Michael W., Norton, Raymond S., Tarcha, Eric J., Londono, Luz M., Sims-Fahey, Brian, Upadhyay, Sanjeev K., Lakey, Jonathan T., Iadonato, Shawn, Wulff, Heike, Beeton, Christine, Chandy, K. George
Published in Toxicon (Oxford) (15.03.2012)
Published in Toxicon (Oxford) (15.03.2012)
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Journal Article
Safety and Pharmacokinetics of LHF-535, a Potential Treatment for Lassa Fever, in Healthy Adults
Amberg, Sean M, Snyder, Benjamin, Vliet-Gregg, Portia A, Tarcha, Eric J, Posakony, Jeff, Bedard, Kristin M, Heald, Alison E
Published in Antimicrobial agents and chemotherapy (15.11.2022)
Published in Antimicrobial agents and chemotherapy (15.11.2022)
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Journal Article
Lassa antiviral LHF-535 protects guinea pigs from lethal challenge
Cashman, Kathleen A., Wilkinson, Eric R., Posakony, Jeffrey, Madu, Ikenna G., Tarcha, Eric J., Lustig, Kurt H., Korth, Marcus J., Bedard, Kristin M., Amberg, Sean M.
Published in Scientific reports (19.11.2022)
Published in Scientific reports (19.11.2022)
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Journal Article
Kv1.3 blockade by ShK186 modulates CD4+ effector memory T-cell activity of patients with granulomatosis with polyangiitis
Lintermans, Lucas L, Stegeman, Coen A, Muñoz-Elías, Ernesto J, Tarcha, Eric J, Iadonato, Shawn P, Rutgers, Abraham, Heeringa, Peter, Abdulahad, Wayel H
Published in Rheumatology (Oxford, England) (04.01.2024)
Published in Rheumatology (Oxford, England) (04.01.2024)
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Journal Article
Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease
Tarcha, Eric J, Chi, Victor, Muñoz-Elías, Ernesto J, Bailey, David, Londono, Luz M, Upadhyay, Sanjeev K, Norton, Kayla, Banks, Amy, Tjong, Indra, Nguyen, Hai, Hu, Xueyou, Ruppert, Greg W, Boley, Scott E, Slauter, Richard, Sams, James, Knapp, Brian, Kentala, Dustin, Hansen, Zachary, Pennington, Michael W, Beeton, Christine, Chandy, K George, Iadonato, Shawn P
Published in The Journal of pharmacology and experimental therapeutics (01.09.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2012)
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Journal Article
Kv1.3 Channel Blockade Modulates the Effector Function of B Cells in Granulomatosis with Polyangiitis
Land, Judith, Lintermans, Lucas L, Stegeman, Coen A, Muñoz-Elías, Ernesto J, Tarcha, Eric J, Iadonato, Shawn P, Heeringa, Peter, Rutgers, Abraham, Abdulahad, Wayel H
Published in Frontiers in immunology (26.09.2017)
Published in Frontiers in immunology (26.09.2017)
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Journal Article
Modulation of the pharmacokinetics of soluble ACE2 decoy receptors through glycosylation
Skeeters, Savanna, Bagale, Kamal, Stepanyuk, Galina, Thieker, David, Aguhob, Aaron, Chan, Kui K., Dutzar, Benjamin, Shalygin, Sergei, Shajahan, Asif, Yang, Xu, DaRosa, Paul A., Frazier, Emily, Sauer, Maximilian M., Bogatzki, Lisa, Byrnes-Blake, Kelly A., Song, Yifan, Azadi, Parastoo, Tarcha, Eric, Zhang, Lianghui, Procko, Erik
Published in Molecular therapy. Methods & clinical development (12.09.2024)
Published in Molecular therapy. Methods & clinical development (12.09.2024)
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Journal Article
879 A promising cancer immunotherapy target: novel fully human agonist antibodies against the human T-cell costimulatory receptor CD27
Guillaudeux, Thierry, Ovechkina, Yulia, Sridhar, Shaarwari, Jurchen, David, Peckham, David, Frazier, Emily, Tarcha, Eric, Iadonato, Shawn
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Evolution of the Mating Type Locus: Insights Gained from the Dimorphic Primary Fungal Pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii
Fraser, James A, Stajich, Jason E, Tarcha, Eric J, Cole, Garry T, Inglis, Diane O, Sil, Anita, Heitman, Joseph
Published in Eukaryotic Cell (01.04.2007)
Published in Eukaryotic Cell (01.04.2007)
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Journal Article
Multivalent Recombinant Protein Vaccine against Coccidioidomycosis
Tarcha, Eric J, Basrur, Venkatesha, Hung, Chiung-Yu, Gardner, Malcolm J, Cole, Garry T
Published in Infection and Immunity (01.10.2006)
Published in Infection and Immunity (01.10.2006)
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Journal Article
Abstract 1637: A fully human anti-vista antibody as a promising therapy against poorly immunogenic tumors
Guillaudeux, Thierry, Tarcha, Eric, Bader, Robert, Dutzar, Benjamin, Eyde, Nathan, Frazier, Emily, Jurchen, David, Lance, Remington, Loomis, Cristina, Lustig, Kurt, Ovechkina, Yulia, Peckham, David, Posakony, Jeff, Sridhar, Shaarwari, Xu, Mei, Iadonato, Shawn
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
항-VISTA 항체 및 이의 용도
TARCHA ERIC J, MIZRAHI RENA AVIVA, LIM YOONG WEARN, IADONATO SHAWN P, JOHNSON DAVID SCOTT, GUILLAUDEUX THIERRY, ADLER ADAM SHULTZ, ASENSIO MICHAEL
Year of Publication 17.11.2023
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Year of Publication 17.11.2023
Patent
Abstract 4261: CD27 a new immuno-oncology target shaping innate and adaptive anti-tumor immune responses
Guillaudeux, Thierry, Ovechkina, Yulia, Sridhar, Shaarwari, Peckham, David, Cross, Jessica, Eyde, Nathan, Frazier, Emily, Kabi, Neda, Lance, Remington, Lustig, Kurt, Xu, Mei, Eric, Tarcha, Iadonato, Shawn
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
182 Highly potent fully human anti-VISTA antibodies – a new target checkpoint inhibitor against immunosuppressive myeloid cells
Guillaudeux, Thierry, Tarcha, Eric, Bader, Robert, Dutzar, Benjamin, Eyde, Nathan, Frazier, Emily, Jurchen, David, Remington, Lance, Loomis, Cristina, Lustig, Kurt, Ovechkina, Yulia, Peckham, David, Shaarwari Sridhar, Xu, Mei, Iadonato, Shawn, Posakony, Jeff
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Durable pharmacological responses from the peptide drug ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease (51.5)
Munoz, Ernesto, Tarcha, Eric, Londono, Luz, Norton, Kayla, Banks, Amy, Chi, Victor, Beeton, Christine, Chandy, K., Iadonato, Shawn
Published in The Journal of immunology (1950) (01.05.2012)
Published in The Journal of immunology (1950) (01.05.2012)
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