Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer
Tanaka, Hiroshi, Sase, Hitoshi, Tsukaguchi, Toshiyuki, Hasegawa, Masami, Tanimura, Hiromi, Yoshida, Miyuki, Sakata, Kiyoaki, Fujii, Toshihiko, Tachibana, Yukako, Takanashi, Kenji, Higashida, Atsuko, Hasegawa, Kiyoshi, Ono, Yoshiyuki, Oikawa, Nobuhiro, Mio, Toshiyuki
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
Get full text
Journal Article
MITF suppression improves the sensitivity of melanoma cells to a BRAF inhibitor
Aida, Satoshi, Sonobe, Yukiko, Tanimura, Hiromi, Oikawa, Nobuhiro, Yuhki, Munehiro, Sakamoto, Hiroshi, Mizuno, Takakazu
Published in Cancer letters (28.11.2017)
Published in Cancer letters (28.11.2017)
Get full text
Journal Article
A long-acting anti-IL-8 antibody improves inflammation and fibrosis in endometriosis
Nishimoto-Kakiuchi, Ayako, Sato, Izumi, Nakano, Kiyotaka, Ohmori, Hiroshi, Kayukawa, Yoko, Tanimura, Hiromi, Yamamoto, Sachiya, Sakamoto, Yuichiro, Nakamura, Genki, Maeda, Atsuhiko, Asanuma, Kentaro, Kato, Atsuhiko, Sankai, Tadashi, Konno, Ryo, Yamada-Okabe, Hisafumi
Published in Science translational medicine (22.02.2023)
Published in Science translational medicine (22.02.2023)
Get more information
Journal Article
YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification
Hamanaka, Natsuki, Nakanishi, Yoshito, Mizuno, Takakazu, Horiguchi-Takei, Kana, Akiyama, Nukinori, Tanimura, Hiromi, Hasegawa, Masami, Satoh, Yasuko, Tachibana, Yukako, Fujii, Toshihiko, Sakata, Kiyoaki, Ogasawara, Kiyomoto, Ebiike, Hirosato, Koyano, Hiroshi, Sato, Haruhiko, Ishii, Nobuya, Mio, Toshiyuki
Published in Cancer research (Chicago, Ill.) (15.11.2019)
Published in Cancer research (Chicago, Ill.) (15.11.2019)
Get full text
Journal Article
Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889
Endo, Mika, Miwa, Masanori, Eda, Hiroyuki, Ura, Masako, Tanimura, Hiromi, Ishikawa, Tohru, Miyazaki‐Nose, Taeko, Hattori, Kazuo, Shimma, Nobuo, Yamada‐Okabe, Hisafumi, Ishitsuka, Hideo
Published in International journal of cancer (20.09.2003)
Published in International journal of cancer (20.09.2003)
Get full text
Journal Article
The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic PIK3CA Mutations
TANAKA, Hiroshi, YOSHIDA, Miyuki, YOSHIMURA, Yasushi, YAMAZAKI, Toshikazu, ISHII, Nobuya, KONDOH, Osamu, AOKI, Yuko, TANIMURA, Hiromi, FUJII, Toshihiko, SAKATA, Kiyoaki, TACHIBANA, Yukako, OHWADA, Jun, EBIIKE, Hirosato, KURAMOTO, Shino, MORITA, Keiichi
Published in Clinical cancer research (15.05.2011)
Published in Clinical cancer research (15.05.2011)
Get full text
Journal Article
Abstract 4179: Potent and selective TRK inhibitor CH7057288
Tanaka, Hiroshi, Sase, Hitoshi, Tsukaguchi, Toshiyuki, Tanimura, Hiromi, Hasegawa, Masami, Hasegawa, Kiyoshi, Ono, Yoshiyuki, Oikawa, Nobuhiro, Sakamoto, Hiroshi, Mio, Toshiyuki
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Abstract B157: Selective class I PI3K inhibitor CH5132799 induces significant tumor regression with suppressing 4E-BP1 phosphorylation
Tanaka, Hiroshi, Yoshida, Miyuki, Tanimura, Hiromi, Ohwada, Jun, Ishii, Nobuya, Kondoh, Osamu, Aoki, Yuko
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
Get full text
Journal Article
water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts
Endo, Mika, Miwa, Masanori, Ura, Masako, Tanimura, Hiromi, Taniguchi, Kenji, Miyazaki, Yoko, Ohwada, Jun, Tsukazaki, Masao, Niizuma, Satoshi, Murata, Takeshi, Ozawa, Sawako, Suda, Hitomi, Ogawa, Kotaro, Nanba, Eitaro, Nagao, Shunsuke, Shimma, Nobuo, Yamada-Okabe, Hisafumi
Published in Cancer chemotherapy and pharmacology (2010)
Published in Cancer chemotherapy and pharmacology (2010)
Get full text
Journal Article
Synthesis of new camptothecin analogs with improved antitumor activities
NIIZUMA, Satoshi, TSUKAZAKI, Masao, YOSHINARI, Kiyoshi, ENDO, Mika, URA, Masako, TANIMURA, Hiromi, MIYAZAKI, Yoko, TAKASUKA, Tsuyoshi, KAWASHIMA, Akira, NANBA, Eitaro, NAKANO, Kounosuke, OGAWA, Kotaro, SUDA, Hitomi, KOBAYASHI, Kazuko, OKABE, Hisafumi, UMEDA, Isao, SHIMMA, Nobuo, MURATA, Takeshi, OHWADA, Jun, OZAWA, Sawako, FUKUDA, Hiroshi, MURASAKI, Chikako, KOHCHI, Masami, MORIKAMI, Kenji
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Get full text
Journal Article
Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog
Ohwada, Jun, Ozawa, Sawako, Kohchi, Masami, Fukuda, Hiroshi, Murasaki, Chikako, Suda, Hitomi, Murata, Takeshi, Niizuma, Satoshi, Tsukazaki, Masao, Ori, Kazutomo, Yoshinari, Kiyoshi, Itezono, Yoshiko, Endo, Mika, Ura, Masako, Tanimura, Hiromi, Miyazaki, Yoko, Kawashima, Akira, Nagao, Shunsuke, Namba, Eitarou, Ogawa, Koutarou, Kobayashi, Kazuko, Okabe, Hisafumi, Umeda, Isao, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Get full text
Journal Article
A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts
ENDO, Mika, MIWA, Masanori, OZAWA, Sawako, SUDA, Hitomi, OGAWA, Kotaro, NANBA, Eitaro, NAGAO, Shunsuke, SHIMMA, Nobuo, YAMADA-OKABE, Hisafumi, URA, Masako, TANIMURA, Hiromi, TANIGUCHI, Kenji, MIYAZAKI, Yoko, OHWADA, Jun, TSUKAZAKI, Masao, NIIZUMA, Satoshi, MURATA, Takeshi
Published in Cancer chemotherapy and pharmacology (2010)
Get full text
Published in Cancer chemotherapy and pharmacology (2010)
Journal Article
Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine
Hattori, Kazuo, Kohchi, Yasunori, Oikawa, Nobuhiro, Suda, Hitomi, Ura, Masako, Ishikawa, Tohru, Miwa, Masanori, Endoh, Mika, Eda, Hiroyuki, Tanimura, Hiromi, Kawashima, Akira, Horii, Ikuo, Ishitsuka, Hideo, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Get full text
Journal Article
COMBINATION OF A PI3K INHIBITOR AND A MEK INHIBITOR
TANAKA HIROSHI, YOSHIDA MIYUKI, KONDOH OSAMU, TOMII YASUSHI, SAKATA KIYOAKI, ISHII NOBUYA, TANIMURA HIROMI
Year of Publication 16.05.2013
Get full text
Year of Publication 16.05.2013
Patent
NOVEL PHARMACEUTICAL COMPOSITION CONTAINING AT LEAST ONE DOLASTATIN 10 DERIVATIVE
AOKI, YUKO, MIWA, MASANORI, YAMAZAKI, TOSHIKAZU, TANIMURA, HIROMI, SAWAMURA, FUMIE
Year of Publication 05.09.2007
Get full text
Year of Publication 05.09.2007
Patent
NOVEL PHARMACEUTICAL COMPOSITION CONTAINING AT LEAST ONE DOLASTATIN 10 DERIVATIVE
AOKI YUKO, SAWAMURA FUMIE, MIWA MASANORI, TANIMURA HIROMI, YAMAZAKI TOSHIKAZU
Year of Publication 27.08.2007
Get full text
Year of Publication 27.08.2007
Patent