Pharmacophore Model for Wnt/Porcupine Inhibitors and Its Use in Drug Design
Poulsen, Anders, Ho, Soo Yei, Wang, Weiling, Alam, Jenefer, Jeyaraj, Duraiswamy A, Ang, Shi Hua, Tan, Eldwin Sum Wai, Lin, Grace Ruiting, Cheong, Vivien Wei Wen, Ke, Zhiyuan, Lee, May Ann, Keller, Thomas H
Published in Journal of chemical information and modeling (27.07.2015)
Published in Journal of chemical information and modeling (27.07.2015)
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Journal Article
이소프레닐시스테인 카복실 메틸트랜스퍼라제의 억제제로 유용한 화합물
HO SOO YEI, POULSEN ANDERS, TAN SUM WAI ELDWIN, ANG SHI HUA, KELLER THOMAS HUGO
Year of Publication 29.07.2020
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Year of Publication 29.07.2020
Patent
Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia
Yang, Haiyan, Chennamaneni, Lohitha Rao, Ho, Melvyn Wai Tuck, Ang, Shi Hua, Tan, Eldwin Sum Wai, Jeyaraj, Duraiswamy Athisayamani, Yeap, Yoon Sheng, Liu, Boping, Ong, Esther Hq, Joy, Joma Kanikadu, Wee, John Liang Kuan, Kwek, Perlyn, Retna, Priya, Dinie, Nurul, Nguyen, Thuy Thi Hanh, Tai, Shi Jing, Manoharan, Vithya, Pendharkar, Vishal, Low, Choon Bing, Chew, Yun Shan, Vuddagiri, Susmitha, Sangthongpitag, Kanda, Choong, Meng Ling, Lee, May Ann, Kannan, Srinivasaraghavan, Verma, Chandra S, Poulsen, Anders, Lim, Sharon, Chuah, Charles, Ong, Tiong Sin, Hill, Jeffrey, Matter, Alex, Nacro, Kassoum
Published in Journal of medicinal chemistry (24.05.2018)
Published in Journal of medicinal chemistry (24.05.2018)
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Journal Article
Scaffold Hopping and Optimization of Maleimide Based Porcupine Inhibitors
Ho, Soo Yei, Alam, Jenefer, Jeyaraj, Duraiswamy Athisayamani, Wang, Weiling, Lin, Grace Ruiting, Ang, Shi Hua, Tan, Eldwin Sum Wai, Lee, May Ann, Ke, Zhiyuan, Madan, Babita, Virshup, David M, Ding, Li Jun, Manoharan, Vithya, Chew, Yun Shan, Low, Choon Bing, Pendharkar, Vishal, Sangthongpitag, Kanda, Hill, Jeffrey, Keller, Thomas H, Poulsen, Anders
Published in Journal of medicinal chemistry (10.08.2017)
Published in Journal of medicinal chemistry (10.08.2017)
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Journal Article
Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors
Kwiatkowski, Jacek, Liu, Boping, Tee, Doris Hui Ying, Chen, Guoying, Ahmad, Nur Huda Binte, Wong, Yun Xuan, Poh, Zhi Ying, Ang, Shi Hua, Tan, Eldwin Sum Wai, Ong, Esther HQ, Nurul Dinie, Poulsen, Anders, Pendharkar, Vishal, Sangthongpitag, Kanda, Lee, May Ann, Sepramaniam, Sugunavathi, Ho, Soo Yei, Cherian, Joseph, Hill, Jeffrey, Keller, Thomas H, Hung, Alvin W
Published in Journal of medicinal chemistry (24.05.2018)
Published in Journal of medicinal chemistry (24.05.2018)
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Journal Article
Discovery and Optimization of a Porcupine Inhibitor
Duraiswamy, Athisayamani Jeyaraj, Lee, May Ann, Madan, Babita, Ang, Shi Hua, Tan, Eldwin Sum Wai, Cheong, Wei Wen Vivien, Ke, Zhiyuan, Pendharkar, Vishal, Ding, Li Jun, Chew, Yun Shan, Manoharan, Vithya, Sangthongpitag, Kanda, Alam, Jenefer, Poulsen, Anders, Ho, Soo Yei, Virshup, David M, Keller, Thomas H
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Journal Article
Probing the Binding Mechanism of Mnk Inhibitors by Docking and Molecular Dynamics Simulations
Kannan, Srinivasaraghavan, Poulsen, Anders, Yang, Hai Yan, Ho, Melvyn, Ang, Shi Hua, Eldwin, Tan Sum Wai, Jeyaraj, Duraiswamy Athisayamani, Chennamaneni, Lohitha Rao, Liu, Boping, Hill, Jeffrey, Verma, Chandra S, Nacro, Kassoum
Published in Biochemistry (Easton) (13.01.2015)
Published in Biochemistry (Easton) (13.01.2015)
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Journal Article
Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria
Ho, Soo Yei, Wang, Weiling, Ng, Fui Mee, Wong, Yun Xuan, Poh, Zhi Ying, Tan, Sum Wai Eldwin, Ang, Shi Hua, Liew, Si Si, Joyner Wong, Yin Sze, Tan, Yvonne, Poulsen, Anders, Pendharkar, Vishal, Sangthongpitag, Kanda, Manchester, John, Basarab, Gregory, Hill, Jeffrey, Keller, Thomas H., Cherian, Joseph
Published in European journal of medicinal chemistry (05.09.2018)
Published in European journal of medicinal chemistry (05.09.2018)
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Journal Article
Correction to Probing the Binding Mechanism of Mnk Inhibitors by Docking and Molecular Dynamics Simulations
Kannan, Srinivasaraghavan, Poulsen, Anders, Yang, Hai Yan, Ho, Melvyn, Ang, Shi Hua, Eldwin, Tan Sum Wai, Jeyaraj, Duraiswamy Athisayamani, Chennamaneni, Lohitha Rao, Liu, Boping, Hill, Jeffrey, Verma, Chandra S, Nacro, Kassoum
Published in Biochemistry (Easton) (07.11.2017)
Published in Biochemistry (Easton) (07.11.2017)
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Journal Article
Abstract 2134: Rational design of selective MNK 1 and 2 kinase inhibitors for the treatment of blast crisis chronic myeloid leukemia patients
Nacro, Kassoum, Yang, Haiyan, Ho, Melvyn Wai Tuck, Yeap, Yoon Sheng, Chennamaneni, Lohitha Rao, Ang, Shi Hua, Tan, Eldwin Sum Wai, Duraiswamy, Athisayamani Jeyaraj, Lim, Sharon, Liu, Boping, Ong, Esther Hongqian, Choong, Meng Ling, Tai, Shi Jing, Manoharan, Vithya, Pendharkar, Vishal, Ding, Lijun, Chew, Yun Shan, Joy, Joma Kanikadu, Kuan, John LW, Kwek, Perlyn Z., Poulsen, Anders, Lee, May Ann, Sangthongpitag, Kanda, Chuah, Charles, Ong, Tiong S., Hill, Jeffrey, Keller, Thomas H., Matter, Alex
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase
Ho, Soo Yei, Poulsen, Anders, Keller, Thomas Hugo, Ang, Shi Hua, Tan, Sum Wai Eldwin
Year of Publication 05.12.2023
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Year of Publication 05.12.2023
Patent
Compounds Useful as Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase
Ho, Soo Yei, Poulsen, Anders, Keller, Thomas Hugo, Ang, Shi Hua, Tan, Sum Wai Eldwin
Year of Publication 06.05.2021
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Year of Publication 06.05.2021
Patent
COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE
KELLER, Thomas Hugo, HO, Soo Yei, ANG, Shi Hua, TAN, Sum Wai Eldwin, POULSEN, Anders
Year of Publication 24.02.2021
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Year of Publication 24.02.2021
Patent
COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE
KELLER, Thomas Hugo, HO, Soo Yei, ANG, Shi Hua, TAN, Sum Wai Eldwin, POULSEN, Anders
Year of Publication 22.07.2020
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Year of Publication 22.07.2020
Patent
Compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase
KELLER, Thomas Hugo, HO, Soo Yei, ANG, Shi Hua, TAN, Sum Wai Eldwin, POULSEN, Anders
Year of Publication 30.04.2020
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Year of Publication 30.04.2020
Patent
COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE
KELLER, Thomas Hugo, HO, Soo Yei, ANG, Shi Hua, TAN, Sum Wai Eldwin, POULSEN, Anders
Year of Publication 29.04.2020
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Year of Publication 29.04.2020
Patent
COMPOUNDS USEFUL AS INHIBITORS OF ISOPRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE
KELLER, Thomas Hugo, HO, Soo Yei, ANG, Shi Hua, TAN, Sum Wai Eldwin, POULSEN, Anders
Year of Publication 21.03.2019
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Year of Publication 21.03.2019
Patent
Compounds useful as inhibitors of isoprenylcysteine carboxyl methyltransferase
HO SOO YEI, POULSEN ANDERS, TAN SUM WAI ELDWIN, ANG SHI HUA, KELLER THOMAS HUGO
Year of Publication 26.06.2020
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Year of Publication 26.06.2020
Patent