Development of a pharmacodynamic assay based on PLCγ2 phosphorylation for quantifying spleen tyrosine kinase (SYK)-Bruton's tyrosine kinase (BTK) signaling
Hsu, Jonathan, Zhang, Jun, Kitson, Chris, Tan, Seng-Lai, Narula, Satwant, DeMartino, Julie A, Liao, Cheng
Published in Journal of biomolecular screening (01.09.2013)
Published in Journal of biomolecular screening (01.09.2013)
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Journal Article
Mechanistic link between the anti-HCV effect of interferon gamma and control of viral replication by a ras-MAPK signaling cascade
YING HUANG, CHEN, Xinyi Cynthia, KONDURI, Madhavi, FOMINA, Nadejda, JIN LU, LING JIN, KOLYKHALOV, Alexander, TAN, Seng-Lai
Published in Hepatology (Baltimore, Md.) (2006)
Published in Hepatology (Baltimore, Md.) (2006)
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Journal Article
Strategies for hepatitis C therapeutic intervention: now and next
Tan, Seng-Lai, He, Yupeng, Huang, Ying, Gale, Michael
Published in Current opinion in pharmacology (01.10.2004)
Published in Current opinion in pharmacology (01.10.2004)
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Journal Article
The Last 10 Amino Acid Residues beyond the Hydrophobic Motif Are Critical for the Catalytic Competence and Function of Protein Kinase Cα
Yeong, Sui Sum, Zhu, Yimin, Smith, Derek, Verma, Chandra, Lim, Wee Guan, Tan, Bee Jen, Li, Qiu Tian, Cheung, Nam Sang, Cai, Minnie, Zhu, Yi-Zhun, Zhou, Shu-Feng, Tan, Seng-Lai, Duan, Wei
Published in The Journal of biological chemistry (13.10.2006)
Published in The Journal of biological chemistry (13.10.2006)
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Journal Article
The very C-terminus of PRK1/PKN is essential for its activation by RhoA and downstream signaling
Lim, Wee Guan, Tan, Bee Jen, Zhu, Yimin, Zhou, Shufeng, Armstrong, Jeffrey S., Li, Qiu Tian, Dong, Qihan, Chan, Eli, Smith, Derek, Verma, Chandra, Tan, Seng-Lai, Duan, Wei
Published in Cellular signalling (01.09.2006)
Published in Cellular signalling (01.09.2006)
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Journal Article
Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R
Huu Tuan Nguyen, Gurvich, Nadia, Gillrie, Mark R, Offeddu, Giovanni, Mouhita Humayun, Kan, Ellen L, Wan, Zhengpeng, Coughlin, Mark Frederick, Zhang, Christie, Vu, Vivian, Wei Ling Lee, Sharon, Seng-Lai, Tan, Barbie, David, Hsu, Jonathan, Kamm, Roger D
Published in bioRxiv (29.11.2023)
Published in bioRxiv (29.11.2023)
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Journal Article
Patient-specific vascularized tumor model: Blocking monocyte recruitment with multispecific antibodies targeting CCR2 and CSF-1R
Nguyen, Huu Tuan, Kan, Ellen L., Humayun, Mouhita, Gurvich, Nadia, Offeddu, Giovanni S., Wan, Zhengpeng, Coughlin, Mark F., Renteria, Diana C., Loew, Andreas, Wilson, Susan, Zhang, Christie, Vu, Vivian, Lee, Sharon Wei Ling, Tan, Seng-Lai, Barbie, David, Hsu, Jonathan, Gillrie, Mark Robert, Kamm, Roger D.
Published in Biomaterials (01.01.2025)
Published in Biomaterials (01.01.2025)
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Journal Article
CELL PENETRATING PEPTIDES WHICH BIND IRF5
PANICKER SANDIP, HUANG KUO SEN, TAN SENG LAI, HOFFMAN ANN, DEMARTINO JULIE, FOTOUHI NADER, SRINIVASAN DINESH, MILLETTI FRANCESCA
Year of Publication 10.06.2015
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Year of Publication 10.06.2015
Patent
First-in-human phase I study of the bifunctional EGFR/TGF β fusion protein BCA101 in patients with EGFR-driven advanced solid cancers
Janku, Filip, Hanna, Glenn J., Carvajal, Richard D., Paik, Paul K., Hernando-Calvo, Alberto, Gillison, Maura L., Fu, Siqing, Wheler, Jennifer J., Bohr, David, Reiners, Ralf, Tan, Seng-Lai, Bilic, Sanela, Bedard, Philippe L.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
Ser2194 Is a Highly Conserved Major Phosphorylation Site of the Hepatitis C Virus Nonstructural Protein NS5A
Katze, Michael G., Kwieciszewski, Bart, Goodlett, David R., Blakely, Collin M., Neddermann, Petra, Tan, Seng-Lai, Aebersold, Rudolph
Published in Virology (New York, N.Y.) (01.12.2000)
Published in Virology (New York, N.Y.) (01.12.2000)
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Journal Article
Abstract 6677: Preliminary immune correlatives from BCA101 trial show favorable modulation of tumor immune microenvironment
Lizotte, Patrick H., Paik, Paul, Niculescu, Liviu, Tan, Seng-Lai H., Bohr, David, Gharakhani, Elham, Reiners, Ralf, Salazar, Rachel, Varshney, Avanish, Krishn, Shiv Ram, Nair, Pradip, Paweletz, Cloud
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
The Cellular Inhibitor of the PKR Protein Kinase, P58IPK, Is an Influenza Virus-activated Co-chaperone That Modulates Heat Shock Protein 70 Activity
Melville, Mark W., Tan, Seng-Lai, Wambach, Marlene, Song, Jaewhan, Morimoto, Richard I., Katze, Michael G.
Published in The Journal of biological chemistry (05.02.1999)
Published in The Journal of biological chemistry (05.02.1999)
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Journal Article
Targeting the SYKaBTK axis for the treatment of immunological and hematological disorders: Recent progress and therapeutic perspectives
Tan, Seng-Lai, Liao, Cheng, Lucas, Matthew C, Stevenson, Christopher, DeMartino, Julie A
Published in Pharmacology & therapeutics (Oxford) (01.05.2013)
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Published in Pharmacology & therapeutics (Oxford) (01.05.2013)
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