In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers
Watanabe, Sumiyo, Hayashi, Kotaro, Toh, Kazuko, Kim, Hyun Jin, Liu, Xueying, Chaya, Hiroyuki, Fukushima, Shigeto, Katsushima, Keisuke, Kondo, Yutaka, Uchida, Satoshi, Ogura, Satomi, Nomoto, Takahiro, Takemoto, Hiroyasu, Cabral, Horacio, Kinoh, Hiroaki, Tanaka, Hiroyoshi Y., Kano, Mitsunobu R., Matsumoto, Yu, Fukuhara, Hiroshi, Uchida, Shunya, Nangaku, Masaomi, Osada, Kensuke, Nishiyama, Nobuhiro, Miyata, Kanjiro, Kataoka, Kazunori
Published in Nature communications (24.04.2019)
Published in Nature communications (24.04.2019)
Get full text
Journal Article
Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles
Yi, Yu, Kim, Hyun Jin, Mi, Peng, Zheng, Meng, Takemoto, Hiroyasu, Toh, Kazuko, Kim, Beob Soo, Hayashi, Kotaro, Naito, Mitsuru, Matsumoto, Yu, Miyata, Kanjiro, Kataoka, Kazunori
Published in Journal of controlled release (28.12.2016)
Published in Journal of controlled release (28.12.2016)
Get full text
Journal Article
Cancerous pH‐responsive polycarboxybetaine‐coated lipid nanoparticle for smart delivery of siRNA against subcutaneous tumor model in mice
Sung, Yi‐Jung, Guo, Haochen, Ghasemizadeh, Aria, Shen, Xin, Chintrakulchai, Wanphiwat, Kobayashi, Motoaki, Toyoda, Masahiro, Ogi, Koichi, Michinishi, Junya, Ohtake, Tomoyuki, Matsui, Makoto, Honda, Yuto, Nomoto, Takahiro, Takemoto, Hiroyasu, Miura, Yutaka, Nishiyama, Nobuhiro
Published in Cancer science (01.12.2022)
Published in Cancer science (01.12.2022)
Get full text
Journal Article
Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy
Nomoto, Takahiro, Yao, Ying, Inoue, Yukiya, Suzuki, Minoru, Kanamori, Kaito, Takemoto, Hiroyasu, Matsui, Makoto, Tomoda, Keishiro, Nishiyama, Nobuhiro
Published in Journal of controlled release (10.04.2021)
Published in Journal of controlled release (10.04.2021)
Get full text
Journal Article
Sequential Self-Assembly Using Tannic Acid and Phenylboronic Acid-Modified Copolymers for Potential Protein Delivery
Honda, Yuto, Nomoto, Takahiro, Matsui, Makoto, Takemoto, Hiroyasu, Kaihara, Yuka, Miura, Yutaka, Nishiyama, Nobuhiro
Published in Biomacromolecules (14.09.2020)
Published in Biomacromolecules (14.09.2020)
Get full text
Journal Article
Intracellular Delivery of Plasmid DNA Using Amphipathic Helical Cell-Penetrating Peptides Containing Dipropylglycine
Naka, Motoki, Umeno, Tomohiro, Shibuya, Mika, Yamaberi, Yuto, Ueda, Atsushi, Tanaka, Masakazu, Takemoto, Hiroyasu, Oba, Makoto
Published in Chemical & pharmaceutical bulletin (29.05.2024)
Published in Chemical & pharmaceutical bulletin (29.05.2024)
Get full text
Journal Article
An Ethylenediamine‐based Switch to Render the Polyzwitterion Cationic at Tumorous pH for Effective Tumor Accumulation of Coated Nanomaterials
Ranneh, Abdul‐Hackam, Takemoto, Hiroyasu, Sakuma, Shunya, Awaad, Aziz, Nomoto, Takahiro, Mochida, Yuki, Matsui, Makoto, Tomoda, Keishiro, Naito, Mitsuru, Nishiyama, Nobuhiro
Published in Angewandte Chemie International Edition (23.04.2018)
Published in Angewandte Chemie International Edition (23.04.2018)
Get full text
Journal Article
Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles
Pittella, Frederico, Cabral, Horacio, Maeda, Yoshinori, Mi, Peng, Watanabe, Sumiyo, Takemoto, Hiroyasu, Kim, Hyun Jin, Nishiyama, Nobuhiro, Miyata, Kanjiro, Kataoka, Kazunori
Published in Journal of controlled release (28.03.2014)
Published in Journal of controlled release (28.03.2014)
Get full text
Journal Article
Potential urinary monitoring of the enhanced permeability and retention effect using MMP-2-responsive poly(ethylene glycol) derivatives
Sun, Xiaohang, Nomoto, Takahiro, Takemoto, Hiroyasu, Matsui, Makoto, Guo, Haochen, Sun, Yudi, Miura, Yutaka, Nishiyama, Nobuhiro
Published in Journal of controlled release (10.01.2021)
Published in Journal of controlled release (10.01.2021)
Get full text
Journal Article
Polymeric ligands comprising sulfur-containing amino acids for targeting tumor-associated amino acid transporters
Guo, Haochen, Xu, Wen, Nomoto, Takahiro, Kanamori, Kaito, Voon, Yan Ming, Honda, Yuto, Yamada, Naoki, Takemoto, Hiroyasu, Matsui, Makoto, Nishiyama, Nobuhiro
Published in Biomaterials (01.02.2023)
Published in Biomaterials (01.02.2023)
Get full text
Journal Article
Sequentially Self-Assembled Nanoreactor Comprising Tannic Acid and Phenylboronic Acid-Conjugated Polymers Inducing Tumor-Selective Enzymatic Activity
Honda, Yuto, Nomoto, Takahiro, Matsui, Makoto, Takemoto, Hiroyasu, Miura, Yutaka, Nishiyama, Nobuhiro
Published in ACS applied materials & interfaces (24.11.2021)
Published in ACS applied materials & interfaces (24.11.2021)
Get full text
Journal Article
Changeable net charge on nanoparticles facilitates intratumor accumulation and penetration
Awaad, Aziz, Takemoto, Hiroyasu, Iizuka, Muneaki, Ogi, Koichi, Mochida, Yuki, Ranneh, Abdul-Hackam, Toyoda, Masahiro, Matsui, Makoto, Nomoto, Takahiro, Honda, Yuto, Hayashi, Kotaro, Tomoda, Keishiro, Ohtake, Tomoyuki, Miura, Yutaka, Nishiyama, Nobuhiro
Published in Journal of controlled release (01.06.2022)
Published in Journal of controlled release (01.06.2022)
Get full text
Journal Article
Poly(N‑isopropylacrylamide)-Based Polymer-Inducing Isothermal Hydrophilic-to-Hydrophobic Phase Transition via Detachment of Hydrophilic Acid-Labile Moiety
Muttaqien, Sjaikhurrizal El, Nomoto, Takahiro, Takemoto, Hiroyasu, Matsui, Makoto, Tomoda, Keishiro, Nishiyama, Nobuhiro
Published in Biomacromolecules (08.04.2019)
Published in Biomacromolecules (08.04.2019)
Get full text
Journal Article
Fine tuning of the net charge alternation of polyzwitterion surfaced lipid nanoparticles to enhance cellular uptake and membrane fusion potential
Homma, Keitaro, Miura, Yutaka, Kobayashi, Motoaki, Chintrakulchai, Wanphiwat, Toyoda, Masahiro, Ogi, Koichi, Michinishi, Junya, Ohtake, Tomoyuki, Honda, Yuto, Nomoto, Takahiro, Takemoto, Hiroyasu, Nishiyama, Nobuhiro
Published in Science and technology of advanced materials (2024)
Published in Science and technology of advanced materials (2024)
Get full text
Journal Article
Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers
Dou, Xuebo, Nomoto, Takahiro, Takemoto, Hiroyasu, Matsui, Makoto, Tomoda, Keishiro, Nishiyama, Nobuhiro
Published in Scientific reports (25.05.2018)
Published in Scientific reports (25.05.2018)
Get full text
Journal Article
Poly(ethylene glycol)–poly(lysine) block copolymer–ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells
Toshiyama, Reishi, Konno, Masamitsu, Eguchi, Hidetoshi, Takemoto, Hiroyasu, Noda, Takehiro, Asai, Ayumu, Koseki, Jun, Haraguchi, Naotsugu, Ueda, Yuji, Matsushita, Katsunori, Asukai, Kei, Ohashi, Tomofumi, Iwagami, Yoshifumi, Yamada, Daisaku, Sakai, Daisuke, Asaoka, Tadafumi, Kudo, Toshihiro, Kawamoto, Koichi, Gotoh, Kunihito, Kobayashi, Shogo, Satoh, Taroh, Doki, Yuichiro, Nishiyama, Nobuhiro, Mori, Masaki, Ishii, Hideshi
Published in Oncogene (01.01.2019)
Published in Oncogene (01.01.2019)
Get full text
Journal Article
Smart Multilayered Assembly for Biocompatible siRNA Delivery Featuring Dissolvable Silica, Endosome-Disrupting Polycation, and Detachable PEG
Suma, Tomoya, Miyata, Kanjiro, Anraku, Yasutaka, Watanabe, Sumiyo, Christie, R. James, Takemoto, Hiroyasu, Shioyama, Momoko, Gouda, Noha, Ishii, Takehiko, Nishiyama, Nobuhiro, Kataoka, Kazunori
Published in ACS nano (28.08.2012)
Published in ACS nano (28.08.2012)
Get full text
Journal Article