Search Results - "TAKEKAWA SHIRO" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Differential effects of selective agonists of neuromedin U1 and U2 receptors in obese and diabetic mice

Differential effects of selective agonists of neuromedin U1 and U2 receptors in obese and diabetic mice

by Nagai, Hiroaki, Kaisho, Tomoko, Yokoyama, Kotaro, Asakawa, Tomoko, Fujita, Hisashi, Matsumiya, Kouta, Noguchi, Jiro, Tsuchimori, Kazue, Nishizawa, Naoki, Kanematsu‐Yamaki, Yoko, Dote, Katsuko, Inooka, Hiroshi, Sakamoto, Jun‐ichi, Ohtaki, Tetsuya, Asami, Taiji, Takekawa, Shiro
Published in British journal of pharmacology (01.01.2018)

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Journal Article

Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2‑selective PEGylated Peptide

Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2‑selective PEGylated Peptide

by Kanematsu-Yamaki, Yoko, Nishizawa, Naoki, Kaisho, Tomoko, Nagai, Hiroaki, Mochida, Taisuke, Asakawa, Tomoko, Inooka, Hiroshi, Dote, Katsuko, Fujita, Hisashi, Matsumiya, Kouta, Hirabayashi, Hideki, Sakamoto, Junichi, Ohtaki, Tetsuya, Takekawa, Shiro, Asami, Taiji
Published in Journal of medicinal chemistry (27.07.2017)

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Journal Article

Discovery of a Novel Series of N‑Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase‑2 Inhibitors

Discovery of a Novel Series of N‑Phenylindoline-5-sulfonamide Derivatives as Potent, Selective, and Orally Bioavailable Acyl CoA:Monoacylglycerol Acyltransferase‑2 Inhibitors

by Sato, Kenjiro, Takahagi, Hiroki, Yoshikawa, Takeshi, Morimoto, Shinji, Takai, Takafumi, Hidaka, Kousuke, Kamaura, Masahiro, Kubo, Osamu, Adachi, Ryutaro, Ishii, Tsuyoshi, Maki, Toshiyuki, Mochida, Taisuke, Takekawa, Shiro, Nakakariya, Masanori, Amano, Nobuyuki, Kitazaki, Tomoyuki
Published in Journal of medicinal chemistry (14.05.2015)

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A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models

A novel and selective melanin-concentrating hormone receptor 1 antagonist ameliorates obesity and hepatic steatosis in diet-induced obese rodent models

by Kawata, Yayoi, Okuda, Shoki, Hotta, Natsu, Igawa, Hideyuki, Takahashi, Masashi, Ikoma, Minoru, Kasai, Shizuo, Ando, Ayumi, Satomi, Yoshinori, Nishida, Mayumi, Nakayama, Masaharu, Yamamoto, Syunsuke, Nagisa, Yasutaka, Takekawa, Shiro
Published in European journal of pharmacology (05.02.2017)

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Journal Article

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization

by Take, Kazumi, Mochida, Taisuke, Maki, Toshiyuki, Satomi, Yoshinori, Hirayama, Megumi, Nakakariya, Masanori, Amano, Nobuyuki, Adachi, Ryutaro, Sato, Kenjiro, Kitazaki, Tomoyuki, Takekawa, Shiro
Published in PloS one (03.03.2016)

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Journal Article

Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors

Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors

by Terao, Yoshito, Suzuki, Hideo, Yoshikawa, Masato, Yashiro, Hiroaki, Takekawa, Shiro, Fujitani, Yasushi, Okada, Kengo, Inoue, Yoshihisa, Yamamoto, Yoshio, Nakagawa, Hideyuki, Yao, Shuhei, Kawamoto, Tomohiro, Uchikawa, Osamu
Published in Bioorganic & medicinal chemistry letters (15.12.2012)

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Journal Article

Versatile live-attenuated SARS-CoV-2 vaccine platform applicable to variants induces protective immunity

Versatile live-attenuated SARS-CoV-2 vaccine platform applicable to variants induces protective immunity

by Yoshida, Akiho, Okamura, Shinya, Torii, Shiho, Komatsu, Sayuri, Miyazato, Paola, Sasaki, Hitomi, Ueno, Shiori, Suzuki, Hidehiko, Kamitani, Wataru, Ono, Chikako, Matsuura, Yoshiharu, Takekawa, Shiro, Yamanishi, Koichi, Ebina, Hirotaka
Published in iScience (18.11.2022)

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Journal Article

Inhibition of MGAT2 modulates fat‐induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high‐fat diet

Inhibition of MGAT2 modulates fat‐induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high‐fat diet

by Mochida, Taisuke, Take, Kazumi, Maki, Toshiyuki, Nakakariya, Masanori, Adachi, Ryutaro, Sato, Kenjiro, Kitazaki, Tomoyuki, Takekawa, Shiro
Published in FEBS open bio (01.03.2020)

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Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities

Optimization of a novel series of N-phenylindoline-5-sulfonamide-based acyl CoA:monoacylglycerol acyltransferase-2 inhibitors: Mitigation of CYP3A4 time-dependent inhibition and phototoxic liabilities

by Sato, Kenjiro, Takahagi, Hiroki, Kubo, Osamu, Hidaka, Kousuke, Yoshikawa, Takeshi, Kamaura, Masahiro, Nakakariya, Masanori, Amano, Nobuyuki, Adachi, Ryutaro, Maki, Toshiyuki, Take, Kazumi, Takekawa, Shiro, Kitazaki, Tomoyuki, Maekawa, Tsuyoshi
Published in Bioorganic & medicinal chemistry (01.08.2015)

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Journal Article

Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines

Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines

by Kamata, Makoto, Yamashita, Toshiro, Imaeda, Toshihiro, Tanaka, Toshio, Masada, Shinichi, Kamaura, Masahiro, Kasai, Shizuo, Hara, Ryoma, Sasaki, Shigekazu, Takekawa, Shiro, Asami, Asano, Kaisho, Tomoko, Suzuki, Nobuhiro, Ashina, Shuntaro, Ogino, Hitomi, Nakano, Yoshihide, Nagisa, Yasutaka, Kato, Koki, Kato, Kaneyoshi, Ishihara, Yuji
Published in Journal of medicinal chemistry (08.03.2012)

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Journal Article

The Nkx6.1 Homeodomain Transcription Factor Suppresses Glucagon Expression and Regulates Glucose-Stimulated Insulin Secretion in Islet Beta Cells

The Nkx6.1 Homeodomain Transcription Factor Suppresses Glucagon Expression and Regulates Glucose-Stimulated Insulin Secretion in Islet Beta Cells

by Schisler, Jonathan C., Jensen, Per Bo, Taylor, David G., Becker, Thomas C., Knop, Filip Krag, Takekawa, Shiro, German, Michael, Weir, Gordon C., Lu, Danhong, Mirmira, Raghavendra G., Newgard, Christopher B., Spiegelman, Bruce M.
Published in Proceedings of the National Academy of Sciences - PNAS (17.05.2005)

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Journal Article

Melanin-concentrating hormone receptor 1 antagonists: Synthesis, structure–activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

Melanin-concentrating hormone receptor 1 antagonists: Synthesis, structure–activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

by Kasai, Shizuo, Kamaura, Masahiro, Kamata, Makoto, Aso, Kazuyoshi, Ogino, Hitomi, Nakano, Yoshihide, Watanabe, Kaoru, Kaisho, Tomoko, Tawada, Michiko, Nagisa, Yasutaka, Takekawa, Shiro, Kato, Koki, Suzuki, Nobuhiro, Ishihara, Yuji
Published in Bioorganic & medicinal chemistry (01.11.2011)

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Journal Article

Identification and Characterization of a Novel Human Cortistatin-like Peptide

Identification and Characterization of a Novel Human Cortistatin-like Peptide

by Fukusumi, Shoji, Kitada, Chieko, Takekawa, Shiro, Kizawa, Hideki, Sakamoto, Junko, Miyamoto, Masaomi, Hinuma, Shuji, Kitano, Kazuaki, Fujino, Masahiko
Published in Biochemical and biophysical research communications (06.03.1997)

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Journal Article

베타 코로나바이러스 약독주

베타 코로나바이러스 약독주

by TAKEKAWA SHIRO, OKAMURA SHINYA, YOSHIDA AKIHO, EBINA HIROTAKA
Year of Publication 28.06.2024

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Patent

BETACORONAVIRUS ATTENUATED STRAIN

BETACORONAVIRUS ATTENUATED STRAIN

by OKAMURA, Shinya, KASHIWABARA, Akiho, TAKEKAWA, Shiro, EBINA, Hirotaka
Year of Publication 11.05.2023

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Patent

Discovery of an artificial peptide agonist to the fibroblast growth factor receptor 1c/βKlotho complex from random peptide T7 phage display

Discovery of an artificial peptide agonist to the fibroblast growth factor receptor 1c/βKlotho complex from random peptide T7 phage display

by Sakamoto, Kotaro, Kawata, Yayoi, Masuda, Yasushi, Umemoto, Tadashi, Ito, Takashi, Asami, Taiji, Takekawa, Shiro, Ohtaki, Tetsuya, Inooka, Hiroshi
Published in Biochemical and biophysical research communications (04.11.2016)

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Journal Article

A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide

A potent and selective natriuretic peptide receptor-3 blocker 11-mer peptide created by hybridization of musclin and atrial natriuretic peptide

by Nishizawa, Naoki, Nakamura, Goshi, Noguchi, Yoko, Nakagawa, Hideyuki, Shimizu, Ayako, Nakayama, Masaharu, Takekawa, Shiro, Asami, Taiji
Published in Bioorganic & medicinal chemistry letters (01.08.2017)

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Journal Article

A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects

A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects

by Inooka, Hiroshi, Sakamoto, Kotaro, Shinohara, Tokuyuki, Masuda, Yasushi, Terada, Michiko, Kumano, Satoshi, Yokoyama, Kotaro, Noguchi, Jiro, Nishizawa, Naoki, Kamiguchi, Hidenori, Fujita, Hisashi, Asami, Taiji, Takekawa, Shiro, Ohtaki, Tetsuya
Published in Bioorganic & medicinal chemistry (15.04.2017)

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Journal Article

Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice

Potent antiobesity effect of a short-length peptide YY-analogue continuously administered in mice

by Nishizawa, Naoki, Niida, Ayumu, Adachi, Yusuke, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Asakawa, Tomoko, Hirabayashi, Hideki, Amano, Nobuyuki, Takekawa, Shiro, Ohtaki, Tetsuya, Asami, Taiji
Published in Bioorganic & medicinal chemistry letters (15.08.2017)

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Journal Article

Highly potent antiobesity effect of a short-length peptide YY analog in mice

Highly potent antiobesity effect of a short-length peptide YY analog in mice

by Nishizawa, Naoki, Niida, Ayumu, Adachi, Yusuke, Kanematsu-Yamaki, Yoko, Masuda, Yasushi, Kumano, Satoshi, Yokoyama, Kotaro, Noguchi, Yoko, Asakawa, Tomoko, Hirabayashi, Hideki, Amano, Nobuyuki, Takekawa, Shiro, Ohtaki, Tetsuya, Asami, Taiji
Published in Bioorganic & medicinal chemistry (15.10.2017)

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