Targeting dependency on a paralog pair of CBP/p300 against de-repression of KREMEN2 in SMARCB1-deficient cancers
Sasaki, Mariko, Kato, Daiki, Murakami, Karin, Yoshida, Hiroshi, Takase, Shohei, Otsubo, Tsuguteru, Ogiwara, Hideaki
Published in Nature communications (05.06.2024)
Published in Nature communications (05.06.2024)
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Journal Article
17β-neriifolin from unripe fruits of Cerbera manghas suppressed cell proliferation via the inhibition of HOXA9-dependent transcription and the induction of apoptosis in the human AML cell line THP-1
Takase, Shohei, Yun, Young Sook, Moriya, Fuki, Sekine, Saaya, Yotsumoto, Satoshi, Miyake, Katsunori, Yahagi, Tadahiro, Ito, Akihiro, Inoue, Hideshi
Published in Journal of natural medicines (01.01.2023)
Published in Journal of natural medicines (01.01.2023)
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Journal Article
A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression
Takase, Shohei, Hiroyama, Takashi, Shirai, Fumiyuki, Maemoto, Yuki, Nakata, Akiko, Arata, Mayumi, Matsuoka, Seiji, Sonoda, Takeshi, Niwa, Hideaki, Sato, Shin, Umehara, Takashi, Shirouzu, Mikako, Nishigaya, Yosuke, Sumiya, Tatsunobu, Hashimoto, Noriaki, Namie, Ryosuke, Usui, Masaya, Ohishi, Tomokazu, Ohba, Shun-Ichi, Kawada, Manabu, Hayashi, Yoshihiro, Harada, Hironori, Yamaguchi, Tokio, Shinkai, Yoichi, Nakamura, Yukio, Yoshida, Minoru, Ito, Akihiro
Published in Nature communications (12.01.2023)
Published in Nature communications (12.01.2023)
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Journal Article
Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents
Nishigaya, Yosuke, Takase, Shohei, Sumiya, Tatsunobu, Kikuzato, Ko, Sato, Tomohiro, Niwa, Hideaki, Sato, Shin, Nakata, Akiko, Sonoda, Takeshi, Hashimoto, Noriaki, Namie, Ryosuke, Honma, Teruki, Umehara, Takashi, Shirouzu, Mikako, Koyama, Hiroo, Yoshida, Minoru, Ito, Akihiro, Shirai, Fumiyuki
Published in Journal of medicinal chemistry (23.03.2023)
Published in Journal of medicinal chemistry (23.03.2023)
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Journal Article
Identification of a derivative of the alkaloid emetine as an inhibitor of the YAP–TEAD interaction and its potential as an anticancer agent
Sekine, Saaya, Takase, Shohei, Hayase, Runa, Noritsugu, Kota, Maemoto, Yuki, Ichikawa, Yasue, Ogawa, Kenji, Kondoh, Yasumitsu, Osada, Hiroyuki, Yoshida, Minoru, Ito, Akihiro
Published in Bioscience, biotechnology, and biochemistry (24.04.2023)
Published in Bioscience, biotechnology, and biochemistry (24.04.2023)
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A quantitative shRNA screen identifies ATP1A1 as a gene that regulates cytotoxicity by aurilide B
Takase, Shohei, Kurokawa, Rumi, Arai, Daisuke, Kanemoto Kanto, Kind, Okino, Tatsufumi, Nakao, Yoichi, Kushiro, Tetsuo, Yoshida, Minoru, Matsumoto, Ken
Published in Scientific reports (17.05.2017)
Published in Scientific reports (17.05.2017)
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Journal Article
Control of the 1,2-rearrangement process by oxidosqualene cyclases during triterpene biosynthesis
Takase, Shohei, Saga, Yusuke, Kurihara, Nozomi, Naraki, Shingo, Kuze, Kenta, Nakata, Genki, Araki, Takeshi, Kushiro, Tetsuo
Published in Organic & biomolecular chemistry (14.07.2015)
Published in Organic & biomolecular chemistry (14.07.2015)
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Journal Article
Plant-Specific Domains and Fragmented Sequences Imply Non-Canonical Functions in Plant Aminoacyl-tRNA Synthetases
Saga, Yusuke, Kawashima, Moeka, Sakai, Shiho, Yamazaki, Kaori, Kaneko, Misato, Takahashi, Moeka, Sato, Natsuko, Toyoda, Yohei, Takase, Shohei, Nakano, Takeshi, Kawakami, Naoto, Kushiro, Tetsuo
Published in Genes (07.09.2020)
Published in Genes (07.09.2020)
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Journal Article
GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain
Kikuchi, Masaki, Takase, Shohei, Konuma, Tsuyoshi, Noritsugu, Kota, Sekine, Saaya, Ikegami, Takahisa, Ito, Akihiro, Umehara, Takashi
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2023)
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Journal Article
Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents
Nishigaya, Yosuke, Takase, Shohei, Sumiya, Tatsunobu, Kikuzato, Ko, Sato, Tomohiro, Niwa, Hideaki, Sato, Shin, Nakata, Akiko, Sonoda, Takeshi, Hashimoto, Noriaki, Namie, Ryosuke, Honma, Teruki, Umehara, Takashi, Shirouzu, Mikako, Koyama, Hiroo, Yoshida, Minoru, Ito, Akihiro, Shirai, Fumiyuki
Published in Journal of medicinal chemistry (23.03.2023)
Published in Journal of medicinal chemistry (23.03.2023)
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Journal Article
Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment
Nishigaya, Yosuke, Takase, Shohei, Sumiya, Tatsunobu, Sato, Tomohiro, Niwa, Hideaki, Sato, Shin, Nakata, Akiko, Matsuoka, Seiji, Maemoto, Yuki, Hashimoto, Noriaki, Namie, Ryosuke, Honma, Teruki, Umehara, Takashi, Shirouzu, Mikako, Koyama, Hiroo, Yoshida, Minoru, Ito, Akihiro, Shirai, Fumiyuki
Published in Bioorganic & medicinal chemistry letters (15.09.2024)
Published in Bioorganic & medicinal chemistry letters (15.09.2024)
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Journal Article
Identification of triterpene biosynthetic genes from Momordica charantia using RNA-seq analysis
Takase, Shohei, Kera, Kota, Hirao, Yuya, Hosouchi, Tsutomu, Kotake, Yuki, Nagashima, Yoshiki, Mannen, Kazuto, Suzuki, Hideyuki, Kushiro, Tetsuo
Published in Bioscience, biotechnology, and biochemistry (01.02.2019)
Published in Bioscience, biotechnology, and biochemistry (01.02.2019)
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Journal Article
Mechanism of Action of Prethioviridamide, an Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptide with a Polythioamide Structure
Takase, Shohei, Kurokawa, Rumi, Kondoh, Yasumitsu, Honda, Kaori, Suzuki, Takehiro, Kawahara, Teppei, Ikeda, Haruo, Dohmae, Naoshi, Osada, Hiroyuki, Shin-ya, Kazuo, Kushiro, Tetsuo, Yoshida, Minoru, Matsumoto, Ken
Published in ACS chemical biology (16.08.2019)
Published in ACS chemical biology (16.08.2019)
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Journal Article
Two Triterpene Synthases from Imperata cylindrica Catalyzing the Formation of a Pair of Diastereoisomers through Boat or Chair Cyclization
Naraki, Shingo, Kakihara, Mai, Kato, Sayuri, Saga, Yusuke, Mannen, Kazuto, Takase, Shohei, Takano, Akihito, Shinpo, Sayaka, Hosouchi, Tsutomu, Nakane, Takahisa, Suzuki, Hideyuki, Kushiro, Tetsuo
Published in Chembiochem : a European journal of chemical biology (02.06.2021)
Published in Chembiochem : a European journal of chemical biology (02.06.2021)
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Journal Article
Allylic hydroxylation of triterpenoids by a plant cytochrome P450 triggers key chemical transformations that produce a variety of bitter compounds
Takase, Shohei, Kera, Kota, Nagashima, Yoshiki, Mannen, Kazuto, Hosouchi, Tsutomu, Shinpo, Sayaka, Kawashima, Moeka, Kotake, Yuki, Yamada, Hiroki, Saga, Yusuke, Otaka, Junnosuke, Araya, Hiroshi, Kotera, Masaaki, Suzuki, Hideyuki, Kushiro, Tetsuo
Published in The Journal of biological chemistry (06.12.2019)
Published in The Journal of biological chemistry (06.12.2019)
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Journal Article
Control of the 1,2-rearrangement process by oxidosqualene cyclases during triterpene biosynthesisElectronic supplementary information (ESI) available. See DOI: 10.1039/c5ob00714c
Takase, Shohei, Saga, Yusuke, Kurihara, Nozomi, Naraki, Shingo, Kuze, Kenta, Nakata, Genki, Araki, Takeshi, Kushiro, Tetsuo
Year of Publication 24.06.2015
Year of Publication 24.06.2015
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