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Published in Journal of the American Chemical Society (06.05.2009)
Published in Journal of the American Chemical Society (06.05.2009)
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Points to consider in establishment of cell substrate used for manufacture of biotechnological products
KISHIOKA, Yasuhiro, TADA, Minoru, KURIBAYASHI, Ryosuke, HORIUCHI, Takayuki, TAKAKURA, Tomoaki, YAMANO-ADACHI, Noriko, MISAKI, Ryou, ISHII, Jun, OTA, Yasumasa, OHYA, Tomoshi, KATAYAMA, Kazuhiko, KAWAHARA, Akihito, KOYAMA, Shingo, SAKASHITA, Hitoshi, TAKIMURA, Yasushi, MORIMOTO, Takuya, NAKANO, Ayuki, HAYAMIZU, Kenji, HYUGA, Masashi, MURAKAMI, Sei, UCHIDA, Kazuhisa, OMASA, Takeshi, AKIKO-ISHII-WATABE
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Suppression of choroidal neovascularization by vasohibin-1, a vascular endothelium-derived angiogenic inhibitor
Wakusawa, Ryosuke, Abe, Toshiaki, Sato, Hajime, Sonoda, Hikaru, Sato, Masaaki, Mitsuda, Yuuichi, Takakura, Tomoaki, Fukushima, Tomi, Onami, Hideyuki, Nagai, Nobuhiro, Ishikawa, Yumi, Nishida, Kohji, Sato, Yasufumi
Published in Investigative ophthalmology & visual science (17.05.2011)
Published in Investigative ophthalmology & visual science (17.05.2011)
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PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates
ZHIJIAN YANG, JUNHUA WANG, DONGDONG ZHANG, YING ZHANG, SHUKUAN LI, XINGHUA SUN, YUYING TAN, YAGI, Shigeo, FRENKEL, Eugene P, HOFFMAN, Robert M, QUAN LU, JINBAO XU, KOBAYASHI, Yoshinao, TAKAKURA, Tomoaki, TAKIMOTO, Akio, YOSHIOKA, Takayuji, CHANGGEN LIAN, CHUNMEI CHEN
Published in Cancer research (Chicago, Ill.) (15.09.2004)
Published in Cancer research (Chicago, Ill.) (15.09.2004)
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Development of Recombinant Methioninase for Cancer Treatment
Hoffman, Robert M, Tan, Yuying, Li, Shukuan, Han, Qinghong, Yagi, Shigeo, Takakura, Tomoaki, Takimoto, Akio, Inagaki, Kenji, Kudou, Daizou
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Endogenous Angiogenesis Inhibitor Vasohibin1 Exhibits Broad-Spectrum Antilymphangiogenic Activity and Suppresses Lymph Node Metastasis
Heishi, Takahiro, Hosaka, Tomoko, Suzuki, Yasuhiro, Miyashita, Hiroki, Oike, Yuichi, Takahashi, Takashi, Nakamura, Takumi, Arioka, Shingo, Mitsuda, Yuichi, Takakura, Tomoaki, Hojo, Kanji, Matsumoto, Mitsunobu, Yamauchi, Chihiro, Ohta, Hideki, Sonoda, Hikaru, Sato, Yasufumi
Published in The American journal of pathology (01.04.2010)
Published in The American journal of pathology (01.04.2010)
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Structure of the Antitumour Enzyme L-Methionine γ-Lyase from Pseudomonas putida at 1.8 Å Resolution
Kudou, Daizou, Misaki, Shintaro, Yamashita, Masao, Tamura, Takashi, Takakura, Tomoaki, Yoshioka, Takayuki, Yagi, Shigeo, Hoffman, Robert M, Takimoto, Akio, Esaki, Nobuyoshi, Inagaki, Kenji
Published in Journal of biochemistry (Tokyo) (01.04.2007)
Published in Journal of biochemistry (Tokyo) (01.04.2007)
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High-level expression and bulk crystallization of recombinant l-methionine γ-lyase, an anticancer agent
Takakura, Tomoaki, Ito, Takaomi, Yagi, Shigeo, Notsu, Yoshihide, Itakura, Takashi, Nakamura, Takumi, Inagaki, Kenji, Esaki, Nobuyoshi, Hoffman, Robert M, Takimoto, Akio
Published in Applied microbiology and biotechnology (01.03.2006)
Published in Applied microbiology and biotechnology (01.03.2006)
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Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine γ-lyase conjugated with polyethylene glycol as an antitumor agent
TAKAKURA, Tomoaki, TAKIMOTO, Akio, YAGI, Shigeo, HOFFMAN, Robert M, ESAKI, Nobuyoshi, NOTSU, Yoshihide, YOSHIDA, Hiroshi, ITO, Takaomi, NAGATOME, Hirofumi, OHNO, Masahiro, KOBAYASHI, Yoshinao, YOSHIOKA, Takayuki, INAGAKI, Kenji
Published in Cancer research (Chicago, Ill.) (01.03.2006)
Published in Cancer research (Chicago, Ill.) (01.03.2006)
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Assay method for antitumor l-methionine γ-lyase: comprehensive kinetic analysis of the complex reaction with l-methionine
Takakura, Tomoaki, Mitsushima, Kenji, Yagi, Shigeo, Inagaki, Kenji, Tanaka, Hidehiko, Esaki, Nobuyoshi, Soda, Kenji, Takimoto, Akio
Published in Analytical biochemistry (15.04.2004)
Published in Analytical biochemistry (15.04.2004)
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Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate
ZHIJIAN YANG, XINGHUA SUN, YOSHIOKA, Takayuki, SUGINAKA, Akinori, FRENKEL, Eugene P, HOFFMAN, Robert M, SHUKUAN LI, YUYING TAN, XIAOEN WANG, NAN ZHANG, YAGI, Shigeo, TAKAKURA, Tomoaki, KOBAYASHI, Yoshinao, TAKIMOTO, Akio
Published in Cancer research (Chicago, Ill.) (15.08.2004)
Published in Cancer research (Chicago, Ill.) (15.08.2004)
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Structure of the Antitumour Enzyme L-Methionine ^g-Lyase from Pseudomonas putida at 1.8 Aa Resolution
Kudou, Daizou, Misaki, Shintaro, Yamashita, Masao, Tamura, Takashi, Takakura, Tomoaki, Yoshioka, Takayuki, Yagi, Shigeo, Hoffman, Robert M, Takimoto, Akio, Esaki, Nobuyoshi, Inagaki, Kenji
Published in Journal of biochemistry (Tokyo) (01.04.2007)
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Published in Journal of biochemistry (Tokyo) (01.04.2007)
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High-level expression and bulk crystallization of recombinant l-methionine [gamma]-lyase, an anticancer agent
Takakura, Tomoaki, Ito, Takaomi, Yagi, Shigeo, Notsu, Yoshihide, Itakura, Takashi, Nakamura, Takumi, Inagaki, Kenji, Esaki, Nobuyoshi, Hoffman, Robert M, Takimoto, Akio
Published in Applied microbiology and biotechnology (01.03.2006)
Published in Applied microbiology and biotechnology (01.03.2006)
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L-METHIONINE DOLLAR G(G)-LYASE WITH MODIFIED FUNCTION
TANAKA, HIDEHIKO, INAGAKI, KENJI, TAKAKURA, TOMOAKI, TAKIMOTO, AKIO, MISAKI, SHINTARO
Year of Publication 14.03.2002
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Year of Publication 14.03.2002
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