Rim domain loops of staphylococcal β-pore forming bi-component toxin S-components recognize target human erythrocytes in a coordinated manner
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Published in Journal of biochemistry (Tokyo) (01.08.2018)
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Novel Low Molecular Weight Spirodiketopiperazine Derivatives Potently Inhibit R5 HIV-1 Infection through Their Antagonistic Effects on CCR5
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Published in The Journal of biological chemistry (14.09.2001)
Published in The Journal of biological chemistry (14.09.2001)
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Characterization of Novel Secreted and Membrane Proteins Isolated by the Signal Sequence Trap Method
Shirozu, Michio, Tada, Hideaki, Tashiro, Kei, Nakamura, Tomoyuki, Lopez, Nelson D., Nazarea, Martina, Hamada, Tsuneyoshi, Sato, Toshihiko, Nakano, Toru, Honjo, Tasuku
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Published in Genomics (San Diego, Calif.) (01.11.1996)
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Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method
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Published in Gene (17.10.1996)
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Design, Synthesis, and Biological Evaluation of the Combinatorial Library with a New Spirodiketopiperazine Scaffold. Discovery of Novel Potent and Selective Low-Molecular-Weight CCR5 Antagonists
Habashita, Hiromu, Kokubo, Masaya, Hamano, Shin-ichi, Hamanaka, Nobuyuki, Toda, Masaaki, Shibayama, Shiro, Tada, Hideaki, Sagawa, Kenji, Fukushima, Daikichi, Maeda, Kenji, Mitsuya, Hiroaki
Published in Journal of medicinal chemistry (13.07.2006)
Published in Journal of medicinal chemistry (13.07.2006)
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Interferon related pericarditis: Review
Nishio, Kazuaki, Arase, Tsutomu, Tada, Hiroko, Tachibana, Hideaki
Published in World journal of cardiology (26.06.2017)
Published in World journal of cardiology (26.06.2017)
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Discovery of orally available spirodiketopiperazine-based CCR5 antagonists
Nishizawa, Rena, Nishiyama, Toshihiko, Hisaichi, Katsuya, Hirai, Keisuke, Habashita, Hiromu, Takaoka, Yoshikazu, Tada, Hideaki, Sagawa, Kenji, Shibayama, Shiro, Maeda, Kenji, Mitsuya, Hiroaki, Nakai, Hisao, Fukushima, Daikichi, Toda, Masaaki
Published in Bioorganic & medicinal chemistry (15.07.2010)
Published in Bioorganic & medicinal chemistry (15.07.2010)
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DIAGNOSIS BIOMARKER FOR IRRITABLE BOWEL SYNDROME
KATSUMATA SEIJI, TADA HIDEAKI, FUKUSHI SHIN, HAYASHI AKIO, MURATA CHIE
Year of Publication 19.05.2016
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Year of Publication 19.05.2016
Patent
Discovery of 4-[4-({(3 R)-1-butyl-3-[( R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride: A highly potent orally available CCR5 selective antagonist
Nishizawa, Rena, Nishiyama, Toshihiko, Hisaichi, Katsuya, Minamoto, Chiaki, Murota, Masayuki, Takaoka, Yoshikazu, Nakai, Hisao, Tada, Hideaki, Sagawa, Kenji, Shibayama, Shiro, Fukushima, Daikichi, Maeda, Kenji, Mitsuya, Hiroaki
Published in Bioorganic & medicinal chemistry (01.07.2011)
Published in Bioorganic & medicinal chemistry (01.07.2011)
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Spirodiketopiperazine-based CCR5 antagonists: Improvement of their pharmacokinetic profiles
Nishizawa, Rena, Nishiyama, Toshihiko, Hisaichi, Katsuya, Hirai, Keisuke, Habashita, Hiromu, Takaoka, Yoshikazu, Tada, Hideaki, Sagawa, Kenji, Shibayama, Shiro, Maeda, Kenji, Mitsuya, Hiroaki, Nakai, Hisao, Fukushima, Daikichi, Toda, Masaaki
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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BIOMARKER FOR DIAGNOSIS OF IRRITABLE BOWEL SYNDROME
KATSUMATA, SEISHI, FUKUDO, SHIN, MURATA, CHIE, HAYASHI, AKIO, TADA, HIDEAKI
Year of Publication 27.08.2015
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Year of Publication 27.08.2015
Patent
Spirodiketopiperazine-based CCR5 antagonists: Lead optimization from biologically active metabolite
Nishizawa, Rena, Nishiyama, Toshihiko, Hisaichi, Katsuya, Matsunaga, Naoki, Minamoto, Chiaki, Habashita, Hiromu, Takaoka, Yoshikazu, Toda, Masaaki, Shibayama, Shiro, Tada, Hideaki, Sagawa, Kenji, Fukushima, Daikichi, Maeda, Kenji, Mitsuya, Hiroaki
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions
Tahara-Hanaoka, Satoko, Someya, Satoru, Shibuya, Kazuko, Shibuya, Akira, Shibayama, Shiro, Fujiki, Akira, Sugiyama, Tetsuya, Hitomi, Kaori, Tada, Hideaki
Published in Nature immunology (01.07.2010)
Published in Nature immunology (01.07.2010)
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Spirodiketopiperazine-based CCR5 antagonist: Discovery of an antiretroviral drug candidate
Nishizawa, Rena, Nishiyama, Toshihiko, Hisaichi, Katsuya, Minamoto, Chiaki, Matsunaga, Naoki, Takaoka, Yoshikazu, Nakai, Hisao, Jenkinson, Stephen, Kazmierski, Wieslaw M., Tada, Hideaki, Sagawa, Kenji, Shibayama, Shiro, Fukushima, Daikichi, Maeda, Kenji, Mitsuya, Hiroaki
Published in Bioorganic & medicinal chemistry letters (15.02.2011)
Published in Bioorganic & medicinal chemistry letters (15.02.2011)
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