Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
Prosz, Aurel, Duan, Haohui, Tisza, Viktoria, Sahgal, Pranshu, Topka, Sabine, Klus, Gregory T., Börcsök, Judit, Sztupinszki, Zsofia, Hanlon, Timothy, Diossy, Miklos, Vizkeleti, Laura, Stormoen, Dag Rune, Csabai, Istvan, Pappot, Helle, Vijai, Joseph, Offit, Kenneth, Ried, Thomas, Sethi, Nilay, Mouw, Kent W., Spisak, Sandor, Pathania, Shailja, Szallasi, Zoltan
Published in Scientific reports (23.11.2023)
Published in Scientific reports (23.11.2023)
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Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression
Diossy, Miklos, Tisza, Viktoria, Li, Hua, Sahgal, Pranshu, Zhou, Jia, Sztupinszki, Zsofia, Young, Denise, Nousome, Darryl, Kuo, Claire, Jiang, Jiji, Chen, Yongmei, Ebner, Reinhard, Sesterhenn, Isabell A., Moncur, Joel T., Chesnut, Gregory T., Petrovics, Gyorgy, Klus, Gregory T., Valcz, Gabor, Nuzzo, Pier Vitale, Ribli, Dezso, Börcsök, Judit, Prosz, Aurel, Krzystanek, Marcin, Ried, Thomas, Szuts, David, Rizwan, Kinza, Kaochar, Salma, Pathania, Shailja, D’Andrea, Alan D., Csabai, Istvan, Srivastava, Shiv, Freedman, Matthew L., Dobi, Albert, Spisak, Sandor, Szallasi, Zoltan
Published in NPJ precision oncology (19.09.2024)
Published in NPJ precision oncology (19.09.2024)
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Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts
Póti, Ádám, Berta, Kinga, Xiao, Yonghong, Pipek, Orsolya, Klus, Gregory T., Ried, Thomas, Csabai, István, Wilcoxen, Keith, Mikule, Keith, Szallasi, Zoltan, Szüts, Dávid
Published in British journal of cancer (27.11.2018)
Published in British journal of cancer (27.11.2018)
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Journal Article
Sequence‐matched probes produce increased cross‐platform consistency and more reproducible biological results in microarray‐based gene expression measurements
Mecham, Brigham H., Klus, Gregory T., Strovel, Jeffrey, Augustus, Meena, Byrne, David, Bozso, Peter, Wetmore, Daniel Z., Mariani, Thomas J., Kohane, Isaac S., Szallasi, Zoltan
Published in Nucleic acids research (2004)
Published in Nucleic acids research (2004)
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Journal Article
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
Prosz, Aurel, Duan, Haohui, Tisza, Viktoria, Sahgal, Pranshu, Topka, Sabine, Tklus, Gregory, Borscok, Judit, Sztupinszki, Zsofia, Hanlon, Timothy, Diossy, Miklos, Vizkeleti, Laura, Stormoen, Dag Rune, Csabai, Istvan, Pappot, Helle, Vijai, Joseph, Offit, Kenneth, Ried, Thomas, Sethi, Nilay, Mouw, Kent W, Spisak, Sandor, Pathania, Shailja, Szallasi, Zoltan
Published in bioRxiv (07.02.2023)
Published in bioRxiv (07.02.2023)
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Paper
Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis
KLUS, G. T, NAKAMURA, J, LI, J.-S, LING, Y.-Z, SON, C, KEMPPAINEN, J. A, WILSON, E. M, BRODIE, A. M. H
Published in Cancer research (Chicago, Ill.) (01.11.1996)
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Published in Cancer research (Chicago, Ill.) (01.11.1996)
Journal Article
17-Imidazolyl, Pyrazolyl, and Isoxazolyl Androstene Derivatives. Novel Steroidal Inhibitors of Human Cytochrome Cl7,20-Lyase (P45017α)
Ling, Yang-zhi, Li, Ji-song, Liu, Yang, Kato, Katsuya, Klus, Gregory T, Brodie, Angela
Published in Journal of medicinal chemistry (26.09.1997)
Published in Journal of medicinal chemistry (26.09.1997)
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Journal Article
Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression without inducing homologous recombination deficiency
Szallasi, Zoltan, Diossy, Miklos, Tisza, Viktoria, Li, Hua, Sahgal, Pranshu, Zhou, Jia, Sztupinszki, Zsofia, Young, Denise, Nuosome, Darryl, Kuo, Claire, Jiang, Jiji, Chen, Yongmei, Ebner, Reinhard, Sesterhenn, Isabell, Moncur, Joel, Chesnut, Gregory, Petrovics, Gyorgy, T Klus, Gregory, Valcz, Gábor, Nuzzo, Pier, Ribli, Dezso, Börcsök, Judit, Prósz, Aurél, Krzystanek, Marcin, Ried, Thomas, Szüts, Dávid, Rizwan, Kinza, Kaochar, Salma, Pathania, Shailja, D'Andrea, Alan, Csabai, István, Srivastava, Shib, Freedman, Matthew, Dobi, Albert, Spisak, Sandor
Published in Research square (01.04.2024)
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Published in Research square (01.04.2024)
Journal Article
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
Prosz, Aurel, Duan, Haohui, Tisza, Viktoria, Sahgal, Pranshu, Topka, Sabine, Klus, Gregory T, Börcsök, Judit, Sztupinszki, Zsofia, Hanlon, Timothy, Diossy, Miklos, Vizkeleti, Laura, Stormoen, Dag Rune, Csabai, Istvan, Pappot, Helle, Vijai, Joseph, Offit, Kenneth, Ried, Thomas, Sethi, Nilay, Mouw, Kent W, Spisak, Sandor, Pathania, Shailja, Szallasi, Zoltan
Published in bioRxiv : the preprint server for biology (07.02.2023)
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Published in bioRxiv : the preprint server for biology (07.02.2023)
Journal Article
Synthesis and in vitro activity of some epimeric 20 alpha-hydroxy, 20-oxime and aziridine pregnene derivatives as inhibitors of human 17 alpha-hydroxylase/C17,20-lyase and 5 alpha-reductase
Ling, Y Z, Li, J S, Kato, K, Liu, Y, Wang, X, Klus, G T, Marat, K, Nnane, I P, Brodie, A M
Published in Bioorganic & medicinal chemistry (01.10.1998)
Published in Bioorganic & medicinal chemistry (01.10.1998)
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Journal Article
Down-regulation of the desmosomal cadherin desmocollin 3 in human breast cancer
Klus, G T, Rokaeus, N, Bittner, M L, Chen, Y, Korz, D M, Sukumar, S, Schick, A, Szallasi, Z
Published in International journal of oncology (01.07.2001)
Published in International journal of oncology (01.07.2001)
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Journal Article
Nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene: A novel and general route to 17-substituted steroids. Part 1 - synthesis of novel 17-azolyl-Δ16 steroids; inhibitors of 17α-hydroxylase/17, 20-lyase (17α-lyase)
Njar, Vincent C.O., Klus, Gregory T., Brodie, Angela M.H.
Published in Bioorganic & medicinal chemistry letters (01.11.1996)
Published in Bioorganic & medicinal chemistry letters (01.11.1996)
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Journal Article
17-Imidazolyl, Pyrazolyl, and Isoxazolyl Androstene Derivatives. Novel Steroidal Inhibitors of Human Cytochrome C l7,20 -Lyase (P450 17α )
Ling, Yang-zhi, Li, Ji-song, Liu, Yang, Kato, Katsuya, Klus, Gregory T., Brodie, Angela
Published in Journal of medicinal chemistry (01.09.1997)
Published in Journal of medicinal chemistry (01.09.1997)
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Journal Article
Nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene: A novel and general route to 17-substituted steroids. Part 1 - synthesis of novel 17-azolyl-Δ 16 steroids; inhibitors of 17α-hydroxylase/17, 20-lyase (17α-lyase)
Njar, Vincent C.O., Klus, Gregory T., Brodie, Angela M.H.
Published in Bioorganic & medicinal chemistry letters (1996)
Published in Bioorganic & medicinal chemistry letters (1996)
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Journal Article
Synthesis and in vitro activity of some epimeric 20α-hydroxy, 20-oxime and aziridine pregnene derivatives as inhibitors of human 17α-hydroxylase/c 17,20 -lyase and 5α-reductase
Ling, Yang-zhi, Li, Ji-song, Kato, Katsuya, Liu, Yang, Wang, Xin, Klus, Gregory T, Marat, Kirk, Nnane, Ivo.P, Brodie, Angela M.H
Published in Bioorganic & medicinal chemistry (01.10.1998)
Published in Bioorganic & medicinal chemistry (01.10.1998)
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Journal Article
Synthesis of novel 21-trifluoropregnane steroids: Inhibitors of 17α-hydroxylase/17,20-lyase (17α-lyase)
Njar, Vincent C.O., Klus, Gregory T., Johnson, Hausa H., Brodie, Angela M.H.
Published in Steroids (01.06.1997)
Published in Steroids (01.06.1997)
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