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Published in British journal of pharmacology (29.01.2009)
Published in British journal of pharmacology (29.01.2009)
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[ 32 P]2‐iodo‐ N 6 ‐methyl‐( N )‐methanocarba‐2′‐deoxyadenosine‐3′,5′‐bisphosphate ([ 32 P]MRS2500), a novel radioligand for quantification of native P2Y 1 receptors
Houston, Dayle, Ohno, Michihiro, Nicholas, Robert A, Jacobson, Kenneth A, Harden, T Kendall
Published in British journal of pharmacology (29.01.2009)
Published in British journal of pharmacology (29.01.2009)
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Dual Activation of Phospholipase C-ϵ by Rho and Ras GTPases
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Published in The Journal of biological chemistry (31.10.2008)
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Quantification of recombinant and platelet P2Y1 receptors utilizing a [125I]-labeled high-affinity antagonist 2-iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate ([125I]MRS2500)
Ohlmann, Philippe, de Castro, Sonia, Brown Jr, Garth G., Gachet, Christian, Jacobson, Kenneth A., Harden, T. Kendall
Published in Pharmacological research (01.10.2010)
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Identification of competitive antagonists of the P2Y1 receptor
Boyer, J L, Romero-Avila, T, Schachter, J B, Harden, T K
Published in Molecular pharmacology (01.11.1996)
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Published in Molecular pharmacology (01.11.1996)
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Pyrimidine Ribonucleotides with Enhanced Selectivity as P2Y 6 Receptor Agonists: Novel 4-Alkyloxyimino, (S)-Methanocarba, and 5′-Triphosphate γ-Ester Modifications
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Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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Pyrimidine Ribonucleotides with Enhanced Selectivity as P2Y6 Receptor Agonists: Novel 4-Alkyloxyimino, (S)-Methanocarba, and 5′-Triphosphate γ-Ester Modificationsa
Maruoka, Hiroshi, Barrett, Matthew O., Ko, Hyojin, Tosh, Dilip K., Melman, Artem, Burianek, Lauren E., Balasubramanian, Ramachandran, Berk, Barkin, Costanzi, Stefano, Harden, T. Kendall, Jacobson, Kenneth A.
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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Functionalized Congeners of P2Y^sub 1^ Receptor Antagonists: 2-Alkynyl (N)-Methanocarba 2'-Deoxyadenosine 3',5'-Bisphosphate Analogues and Conjugation to a Polyamidoamine (PAMAM) Dendrimer Carrier
de Castro, Sonia, Maruoka, Hiroshi, Hong, Kunlun, Kilbey, Michael, Costanzi, Stefano, Hechler, Béatrice, Brown, Garth G, Gachet, Christian, Harden, T Kendall, Jacobson, Kenneth A
Published in Bioconjugate chemistry (21.07.2010)
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Published in Bioconjugate chemistry (21.07.2010)
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Functionalized Congeners of P2Y 1 Receptor Antagonists: 2-Alkynyl ( N )-Methanocarba 2′-Deoxyadenosine 3′,5′-Bisphosphate Analogues and Conjugation to a Polyamidoamine (PAMAM) Dendrimer Carrier
de Castro, Sonia, Maruoka, Hiroshi, Hong, Kunlun, Kilbey, S. Michael, Costanzi, Stefano, Hechler, Béatrice, Brown, Jr, Garth G., Gachet, Christian, Harden, T. Kendall, Jacobson, Kenneth A.
Published in Bioconjugate chemistry (21.07.2010)
Published in Bioconjugate chemistry (21.07.2010)
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Overview of the Alliance for Cellular Signaling
Gilman, Alfred G, Simon, Melvin I, Bourne, Henry R, Harris, Bruce A, Long, Rochelle, Ross, Elliott M, Stull, James T, Taussig, Ronald, Arkin, Adam P, Cobb, Melanie H, Cyster, Jason G, Devreotes, Peter N, Ferrell, James E, Fruman, David, Gold, Michael, Weiss, Arthur, Berridge, Michael J, Cantley, Lewis C, Catterall, William A, Coughlin, Shaun R, Olson, Eric N, Smith, Temple F, Brugge, Joan S, Botstein, David, Dixon, Jack E, Hunter, Tony, Lefkowitz, Robert J, Pawson, Anthony J, Sternberg, Paul W, Varmus, Harold, Subramaniam, Shankar, Sinkovits, Robert S, Li, Joshua, Mock, Dennis, Ning, Yuhong, Saunders, Brian, Sternweis, Paul C, Hilgemann, Donald, Scheuermann, Richard H, DeCamp, Dianne, Hsueh, Robert, Lin, Keng-Mean, Ni, Yan, Seaman, William E, Simpson, Paul C, O'Connell, Timothy D, Roach, Tamara, Choi, Sangdun, Eversole-Cire, Pamela, Fraser, Iain, Mumby, Marc C, Zhao, Yingming, Brekken, Deirdre, Shu, Hongjun, Meyer, Tobias, Chandy, Grischa, Heo, Won Do, Liou, Jen, O'Rourke, Nancy, Verghese, Mary, Mumby, Susanne M, Han, Heping, Brown, H Alex, Forrester, Jeffrey S, Ivanova, Pavlina, Milne, Stephen B, Casey, Patrick J, Harden, T Kendall, Doyle, John, Gray, Martha L, Michnick, Stephen, Schmidt, Martin A, Toner, Mehmet, Tsien, Roger Y, Natarajan, Madhusudan, Ranganathan, Rama, Sambrano, Gilberto R
Published in Nature (London) (12.12.2002)
Published in Nature (London) (12.12.2002)
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Towards a revised nomenclature for P1 and P2 receptors
Fredholm, Bertil B., Abbracchio, Maria P., Burnstock, Geoffrey, Dubyak, George R., Harden, T.Kendall, Jacobson, Kenneth A., Schwabe, Ulrich, Williams, Michael
Published in Trends in pharmacological sciences (Regular ed.) (01.03.1997)
Published in Trends in pharmacological sciences (Regular ed.) (01.03.1997)
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Kinetic Scaffolding Mediated by a Phospholipase C-[beta] and Gq Signaling Complex
Waldo, Gary L, Ricks, Tiffany K, Hicks, Stephanie N, Cheever, Matthew L, Kawano, Takeharu, Tsuboi, Kazuhito, Wang, Xiaoyue, Montell, Craig, Kozasa, Tohru, Sondek, John, T. Kendall Harden
Published in Science (American Association for the Advancement of Science) (12.11.2010)
Published in Science (American Association for the Advancement of Science) (12.11.2010)
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Crystal structure of the multifunctional G[beta]5-RGS9 complex
Cheever, Matthew L, Snyder, Jason T, Gershburg, Svetlana, Siderovski, David P, Harden, T Kendall, Sondek, John
Published in Nature structural & molecular biology (01.02.2008)
Published in Nature structural & molecular biology (01.02.2008)
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Quantification of G i -Mediated Inhibition of Adenylyl Cyclase Activity Reveals That UDP Is a Potent Agonist of the Human P2Y 14 Receptor
Carter, Rhonda L., Fricks, Ingrid P., Barrett, Matthew O., Burianek, Lauren E., Zhou, Yixing, Ko, Hyojin, Das, Arijit, Jacobson, Kenneth A., Lazarowski, Eduardo R., Harden, T. Kendall
Published in Molecular pharmacology (01.12.2009)
Published in Molecular pharmacology (01.12.2009)
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Polyamidoamine (PAMAM) Dendrimer Conjugates of “Clickable” Agonists of the A 3 Adenosine Receptor and Coactivation of the P2Y 14 Receptor by a Tethered Nucleotide
Tosh, Dilip K., Yoo, Lena S., Chinn, Moshe, Hong, Kunlun, Kilbey, S. Michael, Barrett, Matthew O., Fricks, Ingrid P., Harden, T. Kendall, Gao, Zhan-Guo, Jacobson, Kenneth A.
Published in Bioconjugate chemistry (17.02.2010)
Published in Bioconjugate chemistry (17.02.2010)
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Functionalized Congeners of P2Y1 Receptor Antagonists
de Castro, Sonia, Maruoka, Hiroshi, Hong, Kunlun, Kilbey, II, S Michael, Costanzi, Stefano, Hechler, Béatrice, Gachet, Christian, Harden, T. Kendall, Jacobson, Kenneth A.
Published in Bioconjugate chemistry (01.01.2010)
Published in Bioconjugate chemistry (01.01.2010)
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