In vitro reconstitution reveals a key role of human mitochondrial EXOG in RNA primer processing
Karlowicz, Anna, Dubiel, Andrzej B, Czerwinska, Jolanta, Bledea, Adela, Purzycki, Piotr, Grzelewska, Marta, McAuley, Ryan J, Szczesny, Roman J, Brzuska, Gabriela, Krol, Ewelina, Szczesny, Bartosz, Szymanski, Michal R
Published in Nucleic acids research (12.08.2022)
Published in Nucleic acids research (12.08.2022)
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Journal Article
Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymeraseγ
Sohl, Christal D., Szymanski, Michal R., Mislak, Andrea C., Shumate, Christie K., Amiralaei, Sheida, Schinazi, Raymond F., Anderson, Karen S., Yin, Y. Whitney
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
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Journal Article
Biochemical and Biophysical Characterization of the dsDNA Packaging Motor from the Lactococcus lactis Bacteriophage Asccphi28
Reyes-Aldrete, Emilio, Dill, Erik A, Bussetta, Cecile, Szymanski, Michal R, Diemer, Geoffrey, Maindola, Priyank, White, Mark A, Bujalowski, Wlodzimierz M, Choi, Kyung H, Morais, Marc C
Published in Viruses (23.12.2020)
Published in Viruses (23.12.2020)
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Journal Article
Energetics of the Escherichia coli DnaT Protein Trimerization Reaction
Szymanski, Michal R, Jezewska, Maria J, Bujalowski, Wlodzimierz
Published in Biochemistry (Easton) (19.03.2013)
Published in Biochemistry (Easton) (19.03.2013)
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Journal Article
The Escherichia coli PriA Helicase Specifically Recognizes Gapped DNA Substrates
Szymanski, Michal R., Jezewska, Maria J., Bujalowski, Wlodzimierz
Published in The Journal of biological chemistry (01.03.2010)
Published in The Journal of biological chemistry (01.03.2010)
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Journal Article
Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
Szymanski, Michal R, Kuznetsov, Vladmir B, Shumate, Christie, Meng, Qingchao, Lee, Young-Sam, Patel, Gayatri, Patel, Smita, Yin, Y Whitney
Published in The EMBO journal (14.07.2015)
Published in The EMBO journal (14.07.2015)
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Journal Article
Whole exome sequencing identifies a homozygous POLG2 missense variant in an adult patient presenting with optic atrophy, movement disorders, premature ovarian failure and mitochondrial DNA depletion
Dosekova, Petra, Dubiel, Andrzej, Karlowicz, Anna, Zietkiewicz, Szymon, Rydzanicz, Malgorzata, Habalova, Viera, Pienkowski, Victor Murcia, Skirkova, Miriam, Han, Vladimir, Mosejova, Alexandra, Gdovinova, Zuzana, Kaliszewska, Magdalena, Tońska, Katarzyna, Szymanski, Michal R., Skorvanek, Matej, Ploski, Rafal
Published in European journal of medical genetics (01.04.2020)
Published in European journal of medical genetics (01.04.2020)
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Journal Article
Interactions of the Escherichia coli Primosomal PriB Protein with the Single-stranded DNA. Stoichiometries, Intrinsic Affinities, Cooperativities, and Base Specificities
Szymanski, Michal R., Jezewska, Maria J., Bujalowski, Wlodzimierz
Published in Journal of molecular biology (23.04.2010)
Published in Journal of molecular biology (23.04.2010)
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Journal Article
Answer to Finsterer about “Multisystem presentation of a homozygous POLG2 variant”
Dosekova, Petra, Dubiel, Andrzej, Karlowicz, Anna, Zietkiewicz, Szymon, Rydzanicz, Malgorzata, Habalova, Viera, Pienkowski, Victor Murcia, Skirkova, Miriam, Han, Vladimir, Mosejova, Alexandra, Gdovinova, Zuzana, Kaliszewska, Magdalena, Tońska, Katarzyna, Szymanski, Michal R., Skorvanek, Matej, Ploski, Rafal
Published in European journal of medical genetics (01.05.2020)
Published in European journal of medical genetics (01.05.2020)
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Journal Article
The DNA Polymerase Gamma R953C Mutant Is Associated with Antiretroviral Therapy-Induced Mitochondrial Toxicity
Li, Min, Mislak, Andrea C, Foli, Yram, Agbosu, Esinam, Bose, Vivek, Bhandari, Shreya, Szymanski, Michal R, Shumate, Christie K, Yin, Y Whitney, Anderson, Karen S, Paintsil, Elijah
Published in Antimicrobial agents and chemotherapy (01.09.2016)
Published in Antimicrobial agents and chemotherapy (01.09.2016)
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Journal Article
Zinc binding in pestivirus N(pro) is required for interferon regulatory factor 3 interaction and degradation
Szymanski, Michal R, Fiebach, Ana R, Tratschin, Jon-Duri, Gut, Marco, Ramanujam, V M Sadagopa, Gottipati, Keerthi, Patel, Purvi, Ye, Mengyi, Ruggli, Nicolas, Choi, Kyung H
Published in Journal of molecular biology (14.08.2009)
Published in Journal of molecular biology (14.08.2009)
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Journal Article
The Escherichia coli PriA Helicase–Double-Stranded DNA Complex: Location of the Strong DNA-Binding Subsite on the Helicase Domain of the Protein and the Affinity Control by the Two Nucleotide-Binding Sites of the Enzyme
Szymanski, Michal R., Jezewska, Maria J., Bujalowski, Wlodzimierz
Published in Journal of molecular biology (17.09.2010)
Published in Journal of molecular biology (17.09.2010)
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Journal Article
Escherichia coli PriA Helicase Specifically Recognizes Gapped DNA Substrates: EFFECT OF THE TWO NUCLEOTIDE-BINDING SITES OF THE ENZYME ON THE RECOGNITION PROCESS
Szymanski, Michal R, Jezewska, Maria J, Bujalowski, Wlodzimierz
Published in The Journal of biological chemistry (26.03.2010)
Published in The Journal of biological chemistry (26.03.2010)
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Journal Article
Interactions of the Escherichia coli DnaB−DnaC Protein Complex with Nucleotide Cofactors. 1. Allosteric Conformational Transitions of the Complex
Roychowdhury, Anasuya, Szymanski, Michal R, Jezewska, Maria J, Bujalowski, Wlodzimierz
Published in Biochemistry (Easton) (28.07.2009)
Published in Biochemistry (Easton) (28.07.2009)
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Journal Article
Mechanism of NTP Hydrolysis by the Escherichia coli Primary Replicative Helicase DnaB Protein. 2. Nucleotide and Nucleic Acid Specificities
Roychowdhury, Anasuya, Szymanski, Michal R, Jezewska, Maria J, Bujalowski, Wlodzimierz
Published in Biochemistry (Easton) (28.07.2009)
Published in Biochemistry (Easton) (28.07.2009)
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Journal Article