Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species
Szczepanek, Karol, Chen, Qun, Derecka, Marta, Salloum, Fadi N., Zhang, Qifang, Szelag, Magdalena, Cichy, Joanna, Kukreja, Rakesh C., Dulak, Jozef, Lesnefsky, Edward J., Larner, Andrew C.
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
The genomic landscape of metastasis in treatment-naïve breast cancer models
Ross, Christina, Szczepanek, Karol, Lee, Maxwell, Yang, Howard, Qiu, Tinghu, Sanford, Jack D, Hunter, Kent
Published in PLoS genetics (01.05.2020)
Published in PLoS genetics (01.05.2020)
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Journal Article
Integrated analyses of murine breast cancer models reveal critical parallels with human disease
Rennhack, Jonathan P., To, Briana, Swiatnicki, Matthew, Dulak, Caleb, Ogrodzinski, Martin P., Zhang, Yueqi, Li, Caralynn, Bylett, Evan, Ross, Christina, Szczepanek, Karol, Hanrahan, William, Jayatissa, Muthu, Lunt, Sophia Y., Hunter, Kent, Andrechek, Eran R.
Published in Nature communications (22.07.2019)
Published in Nature communications (22.07.2019)
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Journal Article
Function of Mitochondrial Stat3 in Cellular Respiration
Wegrzyn, Joanna, Potla, Ramesh, Chwae, Yong-Joon, Sepuri, Naresh B.V, Zhang, Qifang, Koeck, Thomas, Derecka, Marta, Szczepanek, Karol, Szelag, Magdalena, Gornicka, Agnieszka, Moh, Akira, Moghaddas, Shadi, Chen, Qun, Bobbili, Santha, Cichy, Joanna, Dulak, Jozef, Baker, Darren P, Wolfman, Alan, Stuehr, Dennis, Hassan, Medhat O, Fu, Xin-Yuan, Avadhani, Narayan, Drake, Jennifer I, Fawcett, Paul, Lesnefsky, Edward J, Larner, Andrew C
Published in Science (American Association for the Advancement of Science) (06.02.2009)
Published in Science (American Association for the Advancement of Science) (06.02.2009)
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Journal Article
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations
Pegues, Melissa A., Szczepanek, Karol, Sheikh, Faruk, Thacker, Seth G., Aryal, Baikuntha, Ghorab, Mohamed K, Wolfgang, Steven, Donnelly, Raymond P., Verthelyi, Daniela, Rao, V. Ashutosh
Published in Pharmaceutical research (01.11.2021)
Published in Pharmaceutical research (01.11.2021)
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Journal Article
Metabolic gene remodeling and mitochondrial dysfunction in failing right ventricular hypertrophy secondary to pulmonary arterial hypertension
Gomez-Arroyo, Jose, Mizuno, Shiro, Szczepanek, Karol, Van Tassell, Benjamin, Natarajan, Ramesh, dos Remedios, Cristobal G, Drake, Jennifer I, Farkas, Laszlo, Kraskauskas, Donatas, Wijesinghe, Dayanjan S, Chalfant, Charles E, Bigbee, John, Abbate, Antonio, Lesnefsky, Edward J, Bogaard, Harm J, Voelkel, Norbert F
Published in Circulation. Heart failure (01.01.2013)
Published in Circulation. Heart failure (01.01.2013)
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Journal Article
Metastasis-Specific Gene Expression in Autochthonous and Allograft Mouse Mammary Tumor Models: Stratification and Identification of Targetable Signatures
Ross, Christina, Szczepanek, Karol, Lee, Maxwell, Yang, Howard, Peer, Cody J, Kindrick, Jessica, Shankarappa, Priya, Lin, Zhi-Wei, Sanford, Jack D, Figg, William D, Hunter, Kent W
Published in Molecular cancer research (01.09.2020)
Published in Molecular cancer research (01.09.2020)
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Journal Article
Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury
Szczepanek, Karol, Xu, Aijun, Hu, Ying, Thompson, Jeremy, He, Jun, Larner, Andrew C., Salloum, Fadi N., Chen, Qun, Lesnefsky, Edward J.
Published in Basic research in cardiology (01.11.2015)
Published in Basic research in cardiology (01.11.2015)
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Journal Article
Tyk2 and Stat3 Regulate Brown Adipose Tissue Differentiation and Obesity
Derecka, Marta, Gornicka, Agnieszka, Koralov, Sergei B., Szczepanek, Karol, Morgan, Magdalena, Raje, Vidisha, Sisler, Jennifer, Zhang, Qifang, Otero, Dennis, Cichy, Joanna, Rajewsky, Klaus, Shimoda, Kazuya, Poli, Valeria, Strobl, Birgit, Pellegrini, Sandra, Harris, Thurl E., Seale, Patrick, Russell, Aaron P., McAinch, Andrew J., O’Brien, Paul E., Keller, Susanna R., Croniger, Colleen M., Kordula, Tomasz, Larner, Andrew C.
Published in Cell metabolism (05.12.2012)
Published in Cell metabolism (05.12.2012)
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Journal Article
The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes
Sisler, Jennifer D, Morgan, Magdalena, Raje, Vidisha, Grande, Rebecca C, Derecka, Marta, Meier, Jeremy, Cantwell, Marc, Szczepanek, Karol, Korzun, William J, Lesnefsky, Edward J, Harris, Thurl E, Croniger, Colleen M, Larner, Andrew C
Published in PloS one (21.12.2015)
Published in PloS one (21.12.2015)
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Journal Article
Multi-tasking: nuclear transcription factors with novel roles in the mitochondria
Szczepanek, Karol, Lesnefsky, Edward J, Larner, Andrew C
Published in Trends in cell biology (01.08.2012)
Published in Trends in cell biology (01.08.2012)
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Journal Article
Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727
Zhang, Qifang, Raje, Vidisha, Yakovlev, Vasily A., Yacoub, Adly, Szczepanek, Karol, Meier, Jeremy, Derecka, Marta, Chen, Qun, Hu, Ying, Sisler, Jennifer, Hamed, Hossein, Lesnefsky, Edward J., Valerie, Kristoffer, Dent, Paul, Larner, Andrew C.
Published in The Journal of biological chemistry (25.10.2013)
Published in The Journal of biological chemistry (25.10.2013)
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Journal Article
Lung Cancer Survivorship: Physical, Social, Emotional, and Medical Needs of NSCLC Survivors
Hsu, Melinda L, Guo, Matthew Z, Olson, Sarah, Eaton, Cyd, Boulanger, Mary, Turner, Michelle, Miller, Mattea E, Nguyen, Anna, Szczepanek, Karol, Shenolikar, Rahul, Feliciano, Josephine L
Published in Journal of the National Comprehensive Cancer Network (01.01.2024)
Published in Journal of the National Comprehensive Cancer Network (01.01.2024)
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Journal Article
Reverse electron flow-mediated ROS generation in ischemia-damaged mitochondria: Role of complex I inhibition vs. depolarization of inner mitochondrial membrane
Ross, Thomas, Szczepanek, Karol, Bowler, Elizabeth, Hu, Ying, Larner, Andrew, Lesnefsky, Edward J., Chen, Qun
Published in Biochimica et biophysica acta (01.10.2013)
Published in Biochimica et biophysica acta (01.10.2013)
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Journal Article
Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury
Xu, Aijun, Szczepanek, Karol, Maceyka, Michael W, Ross, Thomas, Bowler, Elizabeth, Hu, Ying, Kenny, Barrett, Mehfoud, Chris, Desai, Pooja N, Baumgarten, Clive M, Chen, Qun, Lesnefsky, Edward J
Published in American Journal of Physiology: Cell Physiology (15.06.2014)
Published in American Journal of Physiology: Cell Physiology (15.06.2014)
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Journal Article
Electron flow into cytochrome c coupled with reactive oxygen species from the electron transport chain converts cytochrome c to a cardiolipin peroxidase: role during ischemia–reperfusion
Aluri, Hema S., Simpson, David C., Allegood, Jeremy C., Hu, Ying, Szczepanek, Karol, Gronert, Scott, Chen, Qun, Lesnefsky, Edward J.
Published in Biochimica et biophysica acta (01.11.2014)
Published in Biochimica et biophysica acta (01.11.2014)
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