Various plasmid strategies limit the effect of bacterial restriction-modification systems against conjugation
Dimitriu, Tatiana, Szczelkun, Mark D, Westra, Edze R
Published in Nucleic acids research (16.10.2024)
Published in Nucleic acids research (16.10.2024)
Get full text
Journal Article
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
Szczelkun, Mark D., Tikhomirova, Maria S., Sinkunas, Tomas, Gasiunas, Giedrius, Karvelis, Tautvydas, Pschera, Patrizia, Siksnys, Virginijus, Seidel, Ralf
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2014)
Get full text
Journal Article
5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage
Mullally, Grace, van Aelst, Kara, Naqvi, Mohsin M, Diffin, Fiona M, Karvelis, Tautvydas, Gasiunas, Giedrius, Siksnys, Virginijus, Szczelkun, Mark D
Published in Nucleic acids research (09.07.2020)
Published in Nucleic acids research (09.07.2020)
Get full text
Journal Article
The Helicase-Like Domains of Type III Restriction Enzymes Trigger Long-Range Diffusion Along DNA
Schwarz, Friedrich W., Tóth, Júlia, van Aelst, Kara, Cui, Guanshen, Clausing, Sylvia, Szczelkun, Mark D., Seidel, Ralf
Published in Science (American Association for the Advancement of Science) (19.04.2013)
Published in Science (American Association for the Advancement of Science) (19.04.2013)
Get full text
Journal Article
Maintaining a sense of direction during long-range communication on DNA
Szczelkun, Mark D, Friedhoff, Peter, Seidel, Ralf
Published in Biochemical Society transactions (01.04.2010)
Published in Biochemical Society transactions (01.04.2010)
Get more information
Journal Article
Type III restriction enzymes communicate in 1D without looping between their target sites
Ramanathan, Subramanian P, van Aelst, Kara, Sears, Alice, Peakman, Luke J, Diffin, Fiona M, Szczelkun, Mark D, Seidel, Ralf
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2009)
Get full text
Journal Article
Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat
van Aelst, Kara, Tóth, Júlia, Ramanathan, Subramanian P, Schwarz, Friedrich W, Seidel, Ralf, Szczelkun, Mark D
Published in Proceedings of the National Academy of Sciences - PNAS (18.05.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (18.05.2010)
Get full text
Journal Article
Evidence for DNA Translocation by the ISWI Chromatin-Remodeling Enzyme
Whitehouse, Iestyn, Stockdale, Chris, Flaus, Andrew, Szczelkun, Mark D., Owen-Hughes, Tom
Published in Molecular and Cellular Biology (01.03.2003)
Published in Molecular and Cellular Biology (01.03.2003)
Get full text
Journal Article
Bacteriostatic antibiotics promote CRISPR-Cas adaptive immunity by enabling increased spacer acquisition
Dimitriu, Tatiana, Kurilovich, Elena, Łapińska, Urszula, Severinov, Konstantin, Pagliara, Stefano, Szczelkun, Mark D., Westra, Edze R.
Published in Cell host & microbe (12.01.2022)
Published in Cell host & microbe (12.01.2022)
Get full text
Journal Article
CRISPR–Cas12a-mediated DNA clamping triggers target-strand cleavage
Naqvi, Mohsin M., Lee, Laura, Montaguth, Oscar E. Torres, Diffin, Fiona M., Szczelkun, Mark D.
Published in Nature chemical biology (01.09.2022)
Published in Nature chemical biology (01.09.2022)
Get full text
Journal Article
Short-range translocation by a restriction enzyme motor triggers diffusion along DNA
Göse, Martin, Magill, Emma E., Hughes-Games, Alex, Shaw, Steven J., Diffin, Fiona M., Rawson, Tara, Nagy, Zsofia, Seidel, Ralf, Szczelkun, Mark D.
Published in Nature chemical biology (01.06.2024)
Published in Nature chemical biology (01.06.2024)
Get full text
Journal Article
Characterization of the Type III restriction endonuclease PstII from Providencia stuartii
Sears, Alice, Peakman, Luke J, Wilson, Geoffrey G, Szczelkun, Mark D
Published in Nucleic acids research (02.12.2019)
Published in Nucleic acids research (02.12.2019)
Get full text
Journal Article
The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape
Maestri, Alice, Pons, Benoit J., Pursey, Elizabeth, Chong, Charlotte E., Gandon, Sylvain, Custodio, Rafael, Olina, Anna, Agapov, Aleksei, Chisnall, Matthew A.W., Grasso, Anita, Paterson, Steve, Szczelkun, Mark D., Baker, Kate S., van Houte, Stineke, Chevallereau, Anne, Westra, Edze R.
Published in Cell host & microbe (14.08.2024)
Published in Cell host & microbe (14.08.2024)
Get full text
Journal Article