The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson's disease
Smith, Jessica K, Mellick, George D, Sykes, Alex M
Published in Frontiers in cellular neuroscience (10.01.2023)
Published in Frontiers in cellular neuroscience (10.01.2023)
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Journal Article
Novel Use of Cell Profiling Technology to Visualize Mitochondrial Responses of Humpback Whale Fibroblasts to Chemical Exposure
Hosen, Md Hafiz All, Sykes, Alex M., Wood, Stephen A., Leusch, Frederic D. L., Whitworth, Deanne J., Bengtson Nash, Susan M.
Published in Environmental science & technology (20.06.2023)
Published in Environmental science & technology (20.06.2023)
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Journal Article
Prolactin stimulates precursor cells in the adult mouse hippocampus
Walker, Tara L, Vukovic, Jana, Koudijs, Margaretha M, Blackmore, Daniel G, Mackay, Eirinn W, Sykes, Alex M, Overall, Rupert W, Hamlin, Adam S, Bartlett, Perry F
Published in PloS one (04.09.2012)
Published in PloS one (04.09.2012)
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Journal Article
Lysophosphatidic Acid Receptor Is a Functional Marker of Adult Hippocampal Precursor Cells
Walker, Tara L., Overall, Rupert W., Vogler, Steffen, Sykes, Alex M., Ruhwald, Susann, Lasse, Daniela, Ichwan, Muhammad, Fabel, Klaus, Kempermann, Gerd
Published in Stem cell reports (12.04.2016)
Published in Stem cell reports (12.04.2016)
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Journal Article
Retinal cell death dependent reactive proliferative gliosis in the mouse retina
Sardar Pasha, Sheik Pran Babu, Münch, Robert, Schäfer, Patrick, Oertel, Peter, Sykes, Alex M., Zhu, Yiqing, Karl, Mike O.
Published in Scientific reports (25.08.2017)
Published in Scientific reports (25.08.2017)
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Journal Article
An Intracellular Domain Fragment of the p75 Neurotrophin Receptor (p75NTR) Enhances Tropomyosin Receptor Kinase A (TrkA) Receptor Function
Matusica, Dusan, Skeldal, Sune, Sykes, Alex M., Palstra, Nickless, Sharma, Aanchal, Coulson, Elizabeth J.
Published in The Journal of biological chemistry (19.04.2013)
Published in The Journal of biological chemistry (19.04.2013)
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Journal Article
Modeling inducible neuropathologies of the retina with differential phenotypes in organoids
Völkner, Manuela, Wagner, Felix, Kurth, Thomas, Sykes, Alex M, Del Toro Runzer, Claudia, Ebner, Lynn J A, Kavak, Cagri, Alexaki, Vasileia Ismini, Cimalla, Peter, Mehner, Mirko, Koch, Edmund, Karl, Mike O
Published in Frontiers in cellular neuroscience (05.05.2023)
Published in Frontiers in cellular neuroscience (05.05.2023)
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Journal Article
Evidence of a Recessively Inherited CCN3 Mutation as a Rare Cause of Early-Onset Parkinsonism
Bentley, Steven R., Khan, Suliman, Öchsner, Marco, Premarathne, Susitha, Aslam, Zain, Fowdar, Javed Y., Iqbal, Jamila, Naeem, Muhammad, Love, Christopher A., Wood, Stephen A., Mellick, George D., Sykes, Alex M.
Published in Frontiers in neurology (15.05.2020)
Published in Frontiers in neurology (15.05.2020)
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Journal Article
ER‐phagy in neurodegeneration
Hill, Melissa A., Sykes, Alex M., Mellick, George D.
Published in Journal of neuroscience research (01.10.2023)
Published in Journal of neuroscience research (01.10.2023)
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Journal Article
ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence
Adusumilli, Vijay S., Walker, Tara L., Overall, Rupert W., Klatt, Gesa M., Zeidan, Salma A., Zocher, Sara, Kirova, Dilyana G., Ntitsias, Konstantinos, Fischer, Tim J., Sykes, Alex M., Reinhardt, Susanne, Dahl, Andreas, Mansfeld, Jörg, Rünker, Annette E., Kempermann, Gerd
Published in Cell stem cell (04.02.2021)
Published in Cell stem cell (04.02.2021)
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Journal Article
Proteomic profiling of idiopathic Parkinson's disease primary patient cells by SWATH‐MS
Wood, Stephen A., Hains, Peter G., Muller, Arnaud, Hill, Melissa, Premarathne, Susitha, Murtaza, Mariyam, Robinson, Phillip J., Mellick, George D., Sykes, Alex M.
Published in Proteomics (Weinheim) (01.09.2022)
Published in Proteomics (Weinheim) (01.09.2022)
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Journal Article
Modelling α-synuclein processing in primary patient cells for pharmacological intervention
Smith, Jessica K., Mellick, George D., Sykes, Alex M.
Published in Exploration of medicine (25.10.2023)
Published in Exploration of medicine (25.10.2023)
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Journal Article
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α–induced excessive erythropoiesis
Franke, Kristin, Kalucka, Joanna, Mamlouk, Soulafa, Singh, Rashim Pal, Muschter, Antje, Weidemann, Alexander, Iyengar, Vasuprada, Jahn, Steffen, Wieczorek, Kathrin, Geiger, Kathrin, Muders, Michael, Sykes, Alex M., Poitz, David M., Ripich, Tatsiana, Otto, Teresa, Bergmann, Sybille, Breier, Georg, Baretton, Gustavo, Fong, Guo-Hua, Greaves, David R., Bornstein, Stefan, Chavakis, Triantafyllos, Fandrey, Joachim, Gassmann, Max, Wielockx, Ben
Published in Blood (21.02.2013)
Published in Blood (21.02.2013)
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Journal Article
Mapping of the Interaction Site between Sortilin and the p75 Neurotrophin Receptor Reveals a Regulatory Role for the Sortilin Intracellular Domain in p75 Neurotrophin Receptor Shedding and Apoptosis
Skeldal, Sune, Sykes, Alex M., Glerup, Simon, Matusica, Dusan, Palstra, Nickless, Autio, Henri, Boskovic, Zoran, Madsen, Peder, Castrén, Eero, Nykjaer, Anders, Coulson, Elizabeth J.
Published in The Journal of biological chemistry (21.12.2012)
Published in The Journal of biological chemistry (21.12.2012)
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Journal Article
The Effects of Transmembrane Sequence and Dimerization on Cleavage of the p75 Neurotrophin Receptor by γ-Secretase
Sykes, Alex M., Palstra, Nickless, Abankwa, Daniel, Hill, Justine M., Skeldal, Sune, Matusica, Dusan, Venkatraman, Prahatha, Hancock, John F., Coulson, Elizabeth J.
Published in The Journal of biological chemistry (21.12.2012)
Published in The Journal of biological chemistry (21.12.2012)
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Journal Article
Apple Peel and Flesh Contain Pro-neurogenic Compounds
Ichwan, Muhammad, Walker, Tara L., Nicola, Zeina, Ludwig-Müller, Jutta, Böttcher, Christoph, Overall, Rupert W., Adusumilli, Vijay S., Bulut, Merve, Sykes, Alex M., Hübner, Norbert, Ramirez-Rodriguez, Gerardo, Ortiz-López, Leonardo, Lugo-Hernández, Enrique A., Kempermann, Gerd
Published in Stem cell reports (09.03.2021)
Published in Stem cell reports (09.03.2021)
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