Sulfated Alginate Reduces Pericapsular Fibrotic Overgrowth on Encapsulated cGMP-Compliant hPSC-Hepatocytes in Mice
Syanda, Adam M, Kringstad, Vera I, Blackford, Samuel J I, Kjesbu, Joachim S, Ng, Soon Seng, Ma, Liang, Xiao, Fang, Coron, Abba E, Rokstad, Anne Mari A, Modi, Sunil, Rashid, S Tamir, Strand, Berit Løkensgard
Published in Frontiers in bioengineering and biotechnology (03.03.2022)
Published in Frontiers in bioengineering and biotechnology (03.03.2022)
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Journal Article
Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency
Li, Chao Zheng, Ogawa, Hiromi, Ng, Soon Seng, Chen, Xindi, Kishimoto, Eriko, Sakabe, Kokoro, Fukami, Aiko, Hu, Yueh-Chiang, Mayhew, Christopher N., Hellmann, Jennifer, Miethke, Alexander, Tasnova, Nahrin L., Blackford, Samuel J.I., Tang, Zu Ming, Syanda, Adam M., Ma, Liang, Xiao, Fang, Sambrotta, Melissa, Tavabie, Oliver, Soares, Filipa, Baker, Oliver, Danovi, Davide, Hayashi, Hisamitsu, Thompson, Richard J., Rashid, S. Tamir, Asai, Akihiro
Published in JHEP reports (01.04.2022)
Published in JHEP reports (01.04.2022)
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Journal Article
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors
Kent, Deniz, Ng, Soon Seng, Syanda, Adam M, Khoshkenar, Payam, Ronzoni, Riccardo, Li, Chao Zheng, Zieger, Marina, Greer, Cindy, Hatch, Stephanie, Segal, Joe, Blackford, Samuel J I, Im, Yu Ri, Chowdary, Vivek, Ismaili, Taylor, Danovi, Davide, Lewis, Patrick A, Irving, James A, Sahdeo, Sunil, Lomas, David A, Ebner, Daniel, Mueller, Christian, Rashid, S Tamir
Published in Hepatology (Baltimore, Md.) (02.07.2024)
Published in Hepatology (Baltimore, Md.) (02.07.2024)
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Journal Article
RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling
Blackford, Samuel J.I., Yu, Tracy T.L., Norman, Michael D.A., Syanda, Adam M., Manolakakis, Michail, Lachowski, Dariusz, Yan, Ziqian, Guo, Yunzhe, Garitta, Elena, Riccio, Federica, Jowett, Geraldine M., Ng, Soon Seng, Vernia, Santiago, del Río Hernández, Armando E., Gentleman, Eileen, Rashid, S. Tamir
Published in Biomaterials (01.02.2023)
Published in Biomaterials (01.02.2023)
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Journal Article
Small molecule screen employing patient-derived iPS hepatocytes identifies LRRK2 as a novel therapeutic target for Alpha1 Antitrypsin Deficiency
Kent, Deniz, Ng, Soon Seng, Khoshkenar, Payam, Syanda, Adam M, Li Chao Zheng, Zieger, Marina, Greer, Cindy, Hatch, Stephanie B, Segal, Joe M, Samuel Ji Blackford, Chowdary, Vivek, Taylor Ismali, Danovi, Davide, Sahdeo, Sunil, Ebner, Daniel, Mueller, Christian, S Tamir Rashid
Published in bioRxiv (17.09.2021)
Published in bioRxiv (17.09.2021)
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