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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia
Stein, Eytan M., DiNardo, Courtney D., Pollyea, Daniel A., Fathi, Amir T., Roboz, Gail J., Altman, Jessica K., Stone, Richard M., DeAngelo, Daniel J., Levine, Ross L., Flinn, Ian W., Kantarjian, Hagop M., Collins, Robert, Patel, Manish R., Frankel, Arthur E., Stein, Anthony, Sekeres, Mikkael A., Swords, Ronan T., Medeiros, Bruno C., Willekens, Christophe, Vyas, Paresh, Tosolini, Alessandra, Xu, Qiang, Knight, Robert D., Yen, Katharine E., Agresta, Sam, de Botton, Stephane, Tallman, Martin S.
Published in Blood (10.08.2017)
Published in Blood (10.08.2017)
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Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia
Swords, Ronan T., Kelly, Kevin R., Smith, Peter G., Garnsey, James J., Mahalingam, Devalingam, Medina, Ernest, Oberheu, Kelli, Padmanabhan, Swaminathan, O'Dwyer, Michael, Nawrocki, Steffan T., Giles, Francis J., Carew, Jennifer S.
Published in Blood (06.05.2010)
Published in Blood (06.05.2010)
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KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study
Swords, Ronan T., Greenberg, Peter L., Wei, Andrew H., Durrant, Simon, Advani, Anjali S., Hertzberg, Mark S., Lewis, Ian D., Rivera, Gabriel, Gratzinger, Dita, Fan, Alice C., Felsher, Dean W., Cortes, Jorge E., Watts, Justin M., Yarranton, Geoff T., Walling, Jackie M., Lancet, Jeffrey E.
Published in Leukemia research (01.11.2016)
Published in Leukemia research (01.11.2016)
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Molecular characterization of newly diagnosed acute myeloid leukemia patients aged 60 years or older: a report from the Beat AML clinical trial
Hoff, Fieke W., Huang, Ying, Welkie, Rina Li, Swords, Ronan T., Traer, Elie, Stein, Eytan M., Lin, Tara L., Patel, Prapti A., Collins, Robert H., Baer, Maria R., Duong, Vu H., Blum, William G., Arellano, Martha L., Stock, Wendy, Odenike, Olatoyosi, Redner, Robert L., Kovacsovics, Tibor, Deininger, Michael W., Zeidner, Joshua F., Olin, Rebecca L., Smith, Catherine C., Foran, James M., Schiller, Gary J., Curran, Emily K., Koenig, Kristin L., Heerema, Nyla A., Chen, Timothy, Martycz, Molly, Stefanos, Mona, Marcus, Sonja G., Rosenberg, Leonard, Druker, Brian J., Levine, Ross L., Burd, Amy, Yocum, Ashley O., Borate, Uma M., Mims, Alice S., Byrd, John C., Madanat, Yazan F.
Published in Blood cancer journal (New York) (03.04.2025)
Published in Blood cancer journal (New York) (03.04.2025)
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Functional genomic landscape of acute myeloid leukaemia
Tyner, Jeffrey W., Tognon, Cristina E., Bottomly, Daniel, Wilmot, Beth, Kurtz, Stephen E., Savage, Samantha L., Long, Nicola, Schultz, Anna Reister, Traer, Elie, Abel, Melissa, Agarwal, Anupriya, Blucher, Aurora, Borate, Uma, Bryant, Jade, Burke, Russell, Carlos, Amy, Carpenter, Richie, Carroll, Joseph, Chang, Bill H., Coblentz, Cody, d’Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T., Degnin, Michie, Devine, Deirdre, Dibb, James, Edwards, David K., Eide, Christopher A., English, Isabel, Glover, Jason, Henson, Rachel, Ho, Hibery, Jemal, Abdusebur, Johnson, Kara, Johnson, Ryan, Junio, Brian, Kaempf, Andy, Leonard, Jessica, Lin, Chenwei, Liu, Selina Qiuying, Lo, Pierrette, Loriaux, Marc M., Luty, Samuel, Macey, Tara, MacManiman, Jason, Martinez, Jacqueline, Mori, Motomi, Nelson, Dylan, Nichols, Ceilidh, Peters, Jill, Ramsdill, Justin, Rofelty, Angela, Schuff, Robert, Searles, Robert, Segerdell, Erik, Smith, Rebecca L., Spurgeon, Stephen E., Sweeney, Tyler, Thapa, Aashis, Visser, Corinne, Wagner, Jake, Watanabe-Smith, Kevin, Werth, Kristen, Wolf, Joelle, White, Libbey, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R., Collins, Robert H., Connolly, Denise C., Deininger, Michael W., Drusbosky, Leylah, Hourigan, Christopher S., Jordan, Craig T., Kropf, Patricia, Lin, Tara L., Martinez, Micaela E., Medeiros, Bruno C., Pallapati, Rachel R., Pollyea, Daniel A., Swords, Ronan T., Watts, Justin M., Weir, Scott J., Wiest, David L., Winters, Ryan M., McWeeney, Shannon K., Druker, Brian J.
Published in Nature (London) (01.10.2018)
Published in Nature (London) (01.10.2018)
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Pevonedistat (MLN4924), a First‐in‐Class NEDD8‐activating enzyme inhibitor, in patients with acute myeloid leukaemia and myelodysplastic syndromes: a phase 1 study
Swords, Ronan T., Erba, Harry P., DeAngelo, Daniel J., Bixby, Dale L., Altman, Jessica K., Maris, Michael, Hua, Zhaowei, Blakemore, Stephen J., Faessel, Hélène, Sedarati, Farhad, Dezube, Bruce J., Giles, Francis J., Medeiros, Bruno C.
Published in British journal of haematology (01.05.2015)
Published in British journal of haematology (01.05.2015)
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Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, combined with azacitidine in patients with AML
Swords, Ronan T., Coutre, Steven, Maris, Michael B., Zeidner, Joshua F., Foran, James M., Cruz, Jose, Erba, Harry P., Berdeja, Jesus G., Tam, Wayne, Vardhanabhuti, Saran, Pawlikowska-Dobler, Iwona, Faessel, Hélène M., Dash, Ajeeta B., Sedarati, Farhad, Dezube, Bruce J., Faller, Douglas V., Savona, Michael R.
Published in Blood (29.03.2018)
Published in Blood (29.03.2018)
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Corrigendum to “KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study” [Leuk. Res. 50 (Nov) (2016) 123–131. PubMed PMID: 27736729]
Swords, Ronan T., Greenberg, Peter L., Wei, Andrew H., Durrant, Simon, Advani, Anjali S., Hertzberg, Mark S., Lewis, Ian D., Rivera, Gabriel, Gratzinger, Dita, Fan, Alice C., Felsher, Dean W., Cortes, Jorge E., Watts, Justin M., Yarranton, Geoff T., Walling, Jackie M., Lancet, Jeffrey E.
Published in Leukemia research (01.08.2017)
Published in Leukemia research (01.08.2017)
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Landscape of somatic mutations and clonal evolution in NUP98‐rearranged adult acute myeloid leukaemia
Frerich, Candace, Li, Peng, Raess, Philipp W., Dunlap, Jennifer, Lachowiez, Curtis, Solis‐Ruiz, Jose, Press, Richard, Long, Nicola, Swords, Ronan T., Wiszniewska, Joanna, Fan, Guang, Xie, Wei
Published in British journal of haematology (01.04.2025)
Published in British journal of haematology (01.04.2025)
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Clinical Responsiveness to All-trans Retinoic Acid Is Potentiated by LSD1 Inhibition and Associated with a Quiescent Transcriptome in Myeloid Malignancies
Tayari, Mina M., Santos, Helena G. Dos, Kwon, Deukwoo, Bradley, Terrence J., Thomassen, Amber, Chen, Charles, Dinh, Yvonne, Perez, Aymee, Zelent, Arthur, Morey, Lluis, Cimmino, Luisa, Shiekhattar, Ramin, Swords, Ronan T., Watts, Justin M.
Published in Clinical cancer research (01.04.2021)
Published in Clinical cancer research (01.04.2021)
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Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies
Kurtz, Stephen E., Eide, Christopher A., Kaempf, Andy, Khanna, Vishesh, Savage, Samantha L., Rofelty, Angela, English, Isabel, Ho, Hibery, Pandya, Ravi, Bolosky, William J., Poon, Hoifung, Deininger, Michael W., Collins, Robert, Swords, Ronan T., Watts, Justin, Pollyea, Daniel A., Medeiros, Bruno C., Traer, Elie, Tognon, Cristina E., Mori, Motomi, Druker, Brian J., Tyner, Jeffrey W.
Published in Proceedings of the National Academy of Sciences - PNAS (05.09.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (05.09.2017)
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A systematic review of higher-risk myelodysplastic syndromes clinical trials to determine the benchmark of azacitidine and explore alternative endpoints for overall survival
Garcia, Jacqueline S., Swords, Ronan T., Roboz, Gail J., Jacoby, Meagan A., Garcia-Manero, Guillermo, Hong, Wan-Jen, Yang, Xiaoqing, Zhou, Ying, Platzbecker, Uwe, Steensma, David P., Wolff, Johannes E., Fenaux, Pierre
Published in Leukemia research (01.05.2021)
Published in Leukemia research (01.05.2021)
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Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study
Swords, Ronan T., Azzam, Diana, Al-Ali, Hassan, Lohse, Ines, Volmar, Claude-Henry, Watts, Justin M., Perez, Aymee, Rodriguez, Ana, Vargas, Fernando, Elias, Roy, Vega, Francisco, Zelent, Arthur, Brothers, Shaun P., Abbasi, Taher, Trent, Jonathan, Rangwala, Shaukat, Deutsch, Yehuda, Conneally, Eibhlin, Drusbosky, Leylah, Cogle, Christopher R., Wahlestedt, Claes
Published in Leukemia research (01.01.2018)
Published in Leukemia research (01.01.2018)
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Entospletinib with decitabine in acute myeloid leukemia with mutant TP53 or complex karyotype: A phase 2 substudy of the Beat AML Master Trial
Duong, Vu H., Ruppert, Amy S., Mims, Alice S., Borate, Uma, Stein, Eytan M., Baer, Maria R., Stock, Wendy, Kovacsovics, Tibor, Blum, William, Arellano, Martha L., Schiller, Gary J., Olin, Rebecca L., Foran, James M., Litzow, Mark R., Lin, Tara L., Patel, Prapti A., Foster, Matthew C., Redner, Robert L., Al‐Mansour, Zeina, Cogle, Christopher R., Swords, Ronan T., Collins, Robert H., Vergilio, Jo‐Anne, Heerema, Nyla A., Rosenberg, Leonard, Yocum, Ashley O., Marcus, Sonja, Chen, Timothy, Druggan, Franchesca, Stefanos, Mona, Gana, Theophilus J., Shoben, Abigail B., Druker, Brian J., Burd, Amy, Byrd, John C., Levine, Ross L., Boyiadzis, Michael M.
Published in Cancer (01.08.2023)
Published in Cancer (01.08.2023)
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A new approach to the treatment of acute myeloid leukaemia targeting the receptor for growth hormone‐releasing hormone
Jimenez, Joaquin J., DelCanto, Gina M., Popovics, Petra, Perez, Aymee, Vila Granda, Ailin, Vidaurre, Irving, Cai, Ren‐Zhi, Rick, Ferenc G., Swords, Ronan T., Schally, Andrew V.
Published in British journal of haematology (01.05.2018)
Published in British journal of haematology (01.05.2018)
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The NEDD8-activating enzyme inhibitor pevonedistat activates the eIF2α and mTOR pathways inducing UPR-mediated cell death in acute lymphoblastic leukemia
Leclerc, Gilles M., Zheng, Shuhua, Leclerc, Guy J., DeSalvo, Joanna, Swords, Ronan T., Barredo, Julio C.
Published in Leukemia research (01.11.2016)
Published in Leukemia research (01.11.2016)
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Myeloid neoplasms with features intermediate between primary myelofibrosis and chronic myelomonocytic leukemia
Chapman, Jennifer, Geyer, Julia T, Khanlari, Mahsa, Moul, Adrienne, Casas, Carmen, Connor, Scot T, Fan, Yao-Shan, Watts, Justin M, Swords, Ronan T, Vega, Francisco, Orazi, Attilio
Published in Modern pathology (01.03.2018)
Published in Modern pathology (01.03.2018)
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Corrigendum to “A systematic review of higher-risk myelodysplastic syndromes clinical trials to determine the benchmark of azacitidine and explore alternative endpoints for overall survival” [Leukemia Res. 104 March (2021)]
Garcia, Jacqueline S., Swords, Ronan T., Roboz, Gail J., Jacoby, Meagan A., Garcia-Manero, Guillermo, Hong, Wan-Jen, Yang, Xiaoqing, Zhou, Ying, Platzbecker, Uwe, Steensma, David P., Wolff, Johannes E., Fenaux, Pierre
Published in Leukemia research (01.06.2021)
Published in Leukemia research (01.06.2021)
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A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy
Watts, Justin, Perez, Aymee, Pereira, Lutecia, Fan, Yao-Shan, Brown, Geoffrey, Vega, Francisco, Petrie, Kevin, Swords, Ronan, Zelent, Arthur
Published in International journal of molecular sciences (11.07.2017)
Published in International journal of molecular sciences (11.07.2017)
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Clinical Correlates of Venetoclax-Based Combination Sensitivities to Augment Acute Myeloid Leukemia Therapy
Eide, Christopher A., Kurtz, Stephen E., Kaempf, Andy, Long, Nicola, Joshi, Sunil Kumar, Nechiporuk, Tamilla, Huang, Ariane, Dibb, Charles A., Taylor, Akosha, Bottomly, Daniel, McWeeney, Shannon K., Minnier, Jessica, Lachowiez, Curtis A., Saultz, Jennifer N., Swords, Ronan T., Agarwal, Anupriya, Chang, Bill H., Druker, Brian J., Tyner, Jeffrey W.
Published in Blood cancer discovery (01.11.2023)
Published in Blood cancer discovery (01.11.2023)
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